A5027652489- Hip and Femur Fractures
- Cardiac, Anesthesia and Surgical Outcomes
- Surgical site infection prevention
- Trauma and Emergency Care Studies
- Bone fractures and treatments
- Orthopaedic implants and arthroplasty
- Pelvic and Acetabular Injuries
- Conducting polymers and applications
- Analytical Chemistry and Sensors
- Surgical Sutures and Adhesives
- Total Knee Arthroplasty Outcomes
- Electrochemical sensors and biosensors
- Anesthesia and Sedative Agents
- Power Systems and Technologies
- Experimental Learning in Engineering
- Algorithms and Data Compression
- Trauma Management and Diagnosis
- Anesthesia and Pain Management
- Health Systems, Economic Evaluations, Quality of Life
- Hip disorders and treatments
- Orthopedic Infections and Treatments
- Bone health and osteoporosis research
- Chronic Disease Management Strategies
- Oral microbiology and periodontitis research
- Bariatric Surgery and Outcomes
Nuffield Orthopaedic Centre
2018-2025
University of Oxford
2018-2025
University of Cape Town
2023
University of KwaZulu-Natal
2023
Institute of Health Economics
2022
Orthopaedic Trauma Association
2022
St George's Hospital
2020
University of Plymouth
2020
John Radcliffe Hospital
2016-2019
University Hospitals Coventry and Warwickshire NHS Trust
2013-2018
Comorbidity measures, such as the Charlson Index (CCI) and Elixhauser Method (EM), are frequently used for risk-adjustment by healthcare researchers. This study sought to create CCI EM lists of Read codes, which standard terminology in some large primary care databases. It also aimed describe compare predictive properties amongst patients with hip fracture (and matched controls) a administrative dataset. Two researchers independently screened 111,929 individual codes populate 17 31...
Introduction Population ageing in Africa is increasing healthcare demands. Hip fractures require multidisciplinary care and are considered an indicator condition for age-related health services. We aimed to estimate current hip fracture incidence Zimbabwe, compare rates against other regional estimates future numbers. Methods All cases adults aged ≥40 years, presenting any hospital Harare over 2 were identified. From this, age- sex-specific per 100 000 person-years estimated using 2022...
Aims The aim of this study was to estimate economic outcomes associated with deep surgical site infection (SSI) in patients an open fracture the lower limb. Patients and Methods A total 460 were recruited from 24 specialist trauma hospitals United Kingdom Major Trauma Network. Preference-based health-related quality-of-life outcomes, assessed using EuroQol EQ-5D-3L 6-Item Short-Form Health Survey questionnaire (SF-6D), costs (£, 2014/2015 prices) measured participant-completed questionnaires...
Background Open fractures of the lower limb occur when a broken bone penetrates skin and is exposed to outside environment. These are life-changing injuries. The risk deep infection may be as high 27%. type dressing applied after surgical debridement could potentially reduce in open-fracture wound. Objectives To assess disability, rate infection, quality life resource use patients with severe open fracture treated negative-pressure wound therapy (NPWT) versus standard management first Design...
We wanted to investigate regional variations in the organisms reported be causing peri-prosthetic infections and report on prophylaxis regimens currently use across England.Analysis of data routinely collected by Public Health England's (PHE) national surgical site infection database elective primary hip knee arthroplasty procedures between April 2010 March 2013 causative organisms. A separate survey 145 hospital Trusts (groups hospitals under local management) England performing and/or was...
Abstract Background Populations in Africa are ageing, hence the number of age-related fragility fractures, including hip is rising. Hip fractures an indicator condition for older adult health provision, as they require a multifaceted pathway care. To enable service planning, detailed national-level understanding current fracture provision needed. Methods The WHO Service Availability & Readiness Assessment survey was modified to evaluate availability, and readiness. All care facilities which...
Aims The aim of this study was to estimate the cost-effectiveness negative-pressure wound therapy (NPWT) in comparison with standard management after initial surgical debridement adults severe open fractures lower limb. Patients and Methods An economic evaluation conducted from perspective United Kingdom NHS Personal Social Services, based on evidence 460 participants Wound Management Open Lower Limb Fractures (WOLLF) trial. Economic outcomes were collected prospectively over 12-month...
This study explores the reported rate of surgical site infection (SSI) after hip fracture surgery in published studies concerning patients treated UK.Studies were included if they on SSI any type treatment for fracture. Each required a minimum 30 days follow-up and 100 patients. Meta-analysis was undertaken using random effects model. Heterogeneity expressed I2 statistic. Risk bias assessed modified Newcastle-Ottawa Scale (NOS) system.There 20 reporting data from 88,615 Most retrospective...
Tin is an ubiquitous element and thus enters mammals through the food chain. It has never been found to be dysfunctional in either plants or animal tissue regarded as innocuous background material. Of many organs glands that have analyzed for tin, only thymus gland exhibits above average value tin. A complete study on tin content published this work attempt investigate subject. Three types of rodents were used study; inbred Lewis rats, A/KI mice (a breast cancer prone mouse) outbred COBS...
This study sought to determine the proportion of older adults with hip fractures captured by a multicentre prospective cohort, World Hip Trauma Evaluation (WHiTE), whether there was evidence selection bias during WHiTE recruitment, and extent which cohort is representative broader population fractures.The characteristics patients recruited into were compared those treated at hospitals same timeframe submitted National Fracture Database (NHFD).Patients more likely be admitted from their own...
The best treatment for fractures of the distal tibia remains controversial. Most these require surgical fixation, but outcomes are unpredictable and complications common. To assess disability, quality life, resource use in patients treated with intramedullary (IM) nail fixation versus locking plate 12 months following a fracture tibia. This was multicentre randomised trial. trial conducted 28 UK acute trauma centres from April 2013 to final follow-up February 2017. In total, 321 adult were...
Aims This study sought to compare the rate of deep surgical site infection (SSI), as measured by Centers for Disease Control and Prevention (CDC) definition, after surgery a fracture hip between patients treated with standard dressings those incisional negative pressure wound therapy (iNPWT). Secondary objectives included determining recruitment willingness participate in trial. Methods The was two-arm multicentre randomized controlled feasibility trial that embedded World Hip Trauma...
Background Major trauma is the leading cause of death in people aged < 45 years. Patients with major usually have lower-limb fractures. Surgery to fix fractures complicated and risk infection may be as high 27%. The type dressing applied after surgery could potentially reduce infection. Objectives To assess deep surgical site rate, disability, quality life, patient assessment scar resource use patients incisions associated following lower limbs treated incisional negative-pressure wound...