A5079621145- Cardiac Structural Anomalies and Repair
- Mechanical Circulatory Support Devices
- Cardiac Valve Diseases and Treatments
- Aortic Disease and Treatment Approaches
- Cardiac Arrest and Resuscitation
- Congenital Heart Disease Studies
- Cardiac pacing and defibrillation studies
- Cardiovascular Function and Risk Factors
- Infective Endocarditis Diagnosis and Management
- Aortic aneurysm repair treatments
- Congenital heart defects research
- Fluid Dynamics and Turbulent Flows
- Wind and Air Flow Studies
- Cardiomyopathy and Myosin Studies
- Tissue Engineering and Regenerative Medicine
- Pulmonary Hypertension Research and Treatments
- Cardiac tumors and thrombi
- Meteorological Phenomena and Simulations
- Cardiac Arrhythmias and Treatments
- Cardiovascular Issues in Pregnancy
- Transplantation: Methods and Outcomes
- Cardiac Imaging and Diagnostics
- Ultrasound in Clinical Applications
- Viral Infections and Immunology Research
- Coronary Artery Anomalies
Kyushu University Hospital
2010-2024
Kyushu University
2012-2024
Japanese Circulation Society
2024
University of Miyazaki
2016
Aso Iizuka Hospital
2013-2014
Yamaguchi University
2014
Nagoya Institute of Technology
2002-2013
Fukuoka Children's Hospital and Medical Center for Infectious Diseases
2010-2011
Asics (Japan)
2011
Hiroshima University
2002
2 JCS/JSCVS/JCC/CVIT 2023 Guideline Focused Update on Indication and Operation of PCPS/ECMO/IMPELLA individual facilities.Therefore, in this Focus Update, specific classes or levels evidence are not strictly mandatory, but rather they presented as expert consensus.However, we strongly hope that will (1) serve a guideline for the standardization PCPS, ECMO, IMPELLA therapy within Japan, (2) be widely used by various healthcare professionals including physicians, nurses, clinical engineers,...
We simulate fractal-generated turbulence (Hurst and Vassilicos 2007 Phys. Fluids 19 035103)) by means of a direct numerical simulation address its fundamental characteristics. examine whether the in upstream region has nature similar to that wake. propose an equation for predicting peak values velocity fluctuation intensity devise method formulating functional form quantity interest focusing on time scale decaying turbulence, we those forms turbulent kinetic energy rms pressure through this...
SUMMARY We attempt to improve accuracy in the high‐wavenumber region DNS of incompressible wall turbulence such as found fully developed turbulent channel flow. In particular, it is shown that improvement viscous terms Navier–Stokes equations leads higher‐order statistics and various spectra. It emphasized increase required computational cost will not be crucial when flow simulated, because introduction a scheme into does for solving Poisson equation. introduced fourth‐order eighth‐order...
Cardiac development and function require actin–myosin interactions in the sarcomere, a highly organized contractile structure. Sarcomere assembly mediated by formin homology 2 domain-containing 3 (Fhod3), member of formins that directs formation straight actin filaments, is essential for embryonic cardiogenesis. However, role Fhod3 neonatal adult stages has remained unknown. Here, we generated floxed mice to bypass lethality an knockout (KO). Perinatal KO heart caused juvenile at around day...
Several studies have shown that sodium-glucose cotransporter-2 inhibitors a renoprotective effect on acute kidney injury (AKI), but their cardiac surgery-associated AKI is unknown.
Significance The actin cytoskeleton in living cells is not static but undergoes dynamic reorganization. Actin-containing thin filaments cardiac sarcomeres are no exception; they exhibit exchange of subunits at the ends within actively contracting cardiomyocytes. Fhod3, an organizer sarcomeres, implicated regulation assembly cardiomyocytes, although mechanism largely unknown. We discovered a direct molecular link between Fhod3 and cMyBP-C, thick myosin filament-associated protein that...
Fhod3 is a cardiac member of the formin family proteins that play pivotal roles in actin filament assembly various cellular contexts. The targeted deletion mouse gene leads to defects cardiogenesis, particularly during myofibrillogenesis, followed by lethality at embryonic day (E) 11.5. However, it remains largely unknown how functions myofibrillogenesis. In this study, assess mechanism whereby regulates myofibrillogenesis we generated transgenic mice expressing selectively cardiomyocytes...
Objectives: Modifications of the Fontan procedure are applied to a wide range complex congenital heart defects with single ventricle physiology. We examined pathway and clinical results extracardiac conduit-total cavopulmonary connection (EC-TCPC) for malpositioned apicocaval juxtaposition. Methods: Of 365 patients who underwent EC-TCPC since 1994, 56 juxtaposition were included in this retrospective study (group 1). The EC was selected after careful consideration preoperative angiography...
A 64-year-old woman underwent surgical resection of a posterior inferior pancreaticoduodenal arterial aneurysm in the subacute phase acute aortic dissection (AAD). Concomitantly, distal pancreatectomy was also required. The approximately 20 mm diameter. Surgical performed because endovascular treatment considered to be technically difficult due dissecting lesions that had remained at abdominal aorta. Histopathological findings suggested this pseudoaneurysm, which arisen as result segmental...
For reversible hydrogen storage properties of 17MgH2 + 12Al ↔ Mg17Al12 17H2, MgH2/Al nanocomposites (I)–(IV) synthesized by ball milling MgH2 and Al (or AlH3) were studied in connection with conditions. The processes consisting two steps effective to improve the behavior; was first milled solutions triethylaluminium (TEA) hexane, followed addition TEA solutions. mixtures further yield nanocomposite (III). In preparing (IV), AlH3 used instead Al. (III) it proved XRD, TDS, DSC PCI that such...
Objective: Lower-limb ischemia is a complication of minimally invasive cardiac surgery with femoral cannulation. Herein, we verified our strategy using distal perfusion cannulation (DPC) against this complication. Methods: We retrospectively assessed 91 cases aortic valve replacement between January 2019 and March 2023. DPC was applied when lower-limb tissue oxygenation index declined by ≥20%. The cannula to artery diameter ratio (C/FA) calculated dividing the size (Fr) divided 3 inner (mm)....
Abstract The formin family proteins have the ability to regulate actin filament assembly, thereby functioning in diverse cytoskeletal processes. Fhod3, a cardiac member of family, plays crucial role development and functional maintenance heart. Although Fhod1, protein closely‐related has been reported be expressed cardiomyocytes, Fhod1 heart still remained elusive. To know physiological heart, we disrupted gene mice by replacement exon 1 with lacZ reporter gene. Histological staining...
Introduction: Ecpella, a combination of veno-arterial (V-A) extracorporeal membrane oxygenation (ECMO) and Impella, may result in the differential hypoxia patients with cardiogenic shock severe lung dysfunction. Here, we report solution this Ecpella-induced unfavorable phenomenon. Case report: A 70-year-old man developed from fulminant myocarditis. As established Ecpella but immediately significant became apparent, ECMO configuration was switched V-A to veno-arteriovenous (V-AV): V-AV newly...
Aortic endografting can cause aortic stiffening. We aimed to determine the chronic effect of thoracic on cardiac afterload, function and remodelling.Eleven dogs were included, all except 1 was successfully assessed [endograft, n = 5; sham operation (control), 5]. deployed a stent graft in descending aorta. The ascending pressure flow measured, input impedance obtained by frequency analysis characteristic arterial compliance. Left ventricular pressure-volume relations measured with an...
Transcatheter aortic valve replacement (TAVR) is a minimally invasive approach to replacement. However, critical cardiovascular collapse can occur during the procedure for various reasons.A 90-year-old man with severe stenosis and left circumflex artery developed acute torrential mitral regurgitation (MR) TAVR. The deployment process induced ventricular dyssynchrony due bundle-branch block myocardial ischemia in region MR. Transesophageal echocardiography clearly demonstrated mechanisms of...