A5035082194- Congenital Heart Disease Studies
- Cardiac Valve Diseases and Treatments
- Cardiac Structural Anomalies and Repair
- Aortic Disease and Treatment Approaches
- Tracheal and airway disorders
- Infective Endocarditis Diagnosis and Management
- Mechanical Circulatory Support Devices
- Pulmonary Hypertension Research and Treatments
- Cardiovascular and Diving-Related Complications
- Cardiac Arrhythmias and Treatments
- Coronary Artery Anomalies
- Cardiovascular Function and Risk Factors
- Cardiovascular Issues in Pregnancy
- Cardiac, Anesthesia and Surgical Outcomes
- Vascular anomalies and interventions
- Trauma Management and Diagnosis
- Cardiac pacing and defibrillation studies
- Pleural and Pulmonary Diseases
- Cardiac Imaging and Diagnostics
- Viral Infections and Immunology Research
- Renal and Vascular Pathologies
- Cardiac and Coronary Surgery Techniques
- Aortic aneurysm repair treatments
- Cardiovascular Effects of Exercise
- Apelin-related biomedical research
Miyagi Children's Hospital
2021-2025
Kyushu University Hospital
2004-2024
Fukuoka Children's Hospital and Medical Center for Infectious Diseases
2004-2021
Kyushu University
2003-2021
Amyloidosis Foundation
2021
Research Network (United States)
2021
Kumamoto City Hospital
2014
Boston Children's Hospital
2014
Kanagawa Children's Medical Center
2012
Fukuoka University
2004
Background— Prognosis of ischemic cardiomyopathy still remains poor because the lack effective treatments. To develop a noninvasive therapy for disorder, we examined in vitro and vivo effects extracorporeal shock wave (SW) that could enhance angiogenesis. Methods Results— SW treatment applied to cultured human umbilical vein endothelial cells significantly upregulated mRNA expression vascular growth factor its receptor Flt-1 vitro. A porcine model chronic myocardial ischemia was made by...
This single-institution study aimed to evaluate the early mid-term outcomes of extracardiac conduit total cavopulmonary connection (EC-TCPC).Between March 1994 and 2014, 500 patients (median age, 3.4 years) underwent EC-TCPC at our hospital. One hundred twenty-three (24.6%) showed heterotaxy, fenestration was created in 6 (1.2%). The standard institutional treatment policy included postoperative anticoagulation individualized cardiovascular medication. mortality morbidity rates, haemodynamic...
To review the surgical outcome of Yasui operation in patients with adequate-sized ventricles and ventricular septal defect (VSD) associated obstructions aortic arch left outflow tract (LVOT). Since 1985, 17 have undergone at our institution. Interrupted was present 11 coarctation aorta/hypoplastic 6. Twelve had stenosis, 5 atresia. The minimum diameter LVOT z-score stenosis were 3.7 ± 0.4 mm −9.2 1.2, respectively. Primary repair performed 6 patients, staged, bilateral pulmonary artery...
Background:The long-term results of aortic valve replacement (AVR; n=737) with bileaflet mechanical prosthesis (MP) or Carpentier-Edwards Perimount bioprostheses (BP) were evaluated in different age groups.Methods and Results:Since 1981, a total 737 prostheses (424 MP vs. 313 BP) implanted for AVR 278 patients aged ≥70 years (79 199 BP), 191 60–69 (128 63 268 <60 (217 51 BP). Follow-up was completed 6,523 patient-years 98.5% cases. Among the years, both actuarial survival rate (P=0.0434)...
Introduction of the bidirectional Glenn procedure (BDG) in low-risk Fontan candidates would improve clinical outcomes. Over last decade, not only high-risk candidates, but all underwent BDG and staged operation (TCPC) our hospital.Three hundred thirty-three consecutive patients (age range, 42 days to 16 years old) at Fukuoka Children's Hospital Medical Center from 1992 2004. Diagnoses included hypoplastic left heart syndrome 47, pulmonary atresia with intact ventricular septum 32, tricuspid...
We sought to examine our long-term results of mitral valve (MV) repair with expanded polytetrafluoroethylene (ePTFE) sutures and determine the predictors for outcome this procedure. Between 1995 2011, MV chordal reconstruction by artificial chordae was achieved in 78 patients (34 males 44 females). Median age at 1.5 years (range 3.6 months–13.4) weight 9.1 kg (2.5–31.4). The mean follow-up 8.3 years. A Cox proportional hazards model used analyse risk factors a composite death, conversion...
Abstract A yellow sulfatotungstate complex was formed by heating a 50 mM W(VI)–2 M H2SO4–40% (v/v) CH3CN system at 70 °C for 14 days, being isolated as the tetrapropylammonium (n-Pr4N+) salt. An X-ray structural analysis (ortho-rhombic, Pca21 (No. 29) = 27.181(1), b 14.1428(6), c 27.7292(9) Å, and Z 4) revealed that structure consists of an α-Dawson-type [S2W18O62]4− anion. The α-[S2W18O62]4− underwent four-step reversible one-electron reduction in CH3CN, presence acid caused waves to be...
Infective endocarditis (IE) in patients with adult congenital heart disease (ACHD) remains a diagnostic challenge due to difficulties detecting endocardial lesions by echocardiography.
Background:The long-term results achieved with aortic St. Jude Medical (SJM) mechanical prostheses in various age groups of Japanese patients have not been previously compared or reported.Methods and Results:Since 1981, a total 240 SJM valves were implanted 79 using the Standard model, 58 Hemodynamic Plus 103 Regent model for valve replacement (AVR). Follow-up was completed 2,397 patient-years 97.5% patients, among whom effect compared, subjects divided into younger (<65 years) older (≥65...
Aortic endografting can cause aortic stiffening. We aimed to determine the chronic effect of thoracic on cardiac afterload, function and remodelling.Eleven dogs were included, all except 1 was successfully assessed [endograft, n = 5; sham operation (control), 5]. deployed a stent graft in descending aorta. The ascending pressure flow measured, input impedance obtained by frequency analysis characteristic arterial compliance. Left ventricular pressure-volume relations measured with an...
Background— Monocyte chemoattractant protein-1 (MCP-1), a potent chemotactic factor for monocytes, is induced during ischemia-reperfusion. As monocytes might play an important causative role in reperfusion injury, we investigated if inhibition of monocyte activation could attenuate ischemia-reperfusion injury and thereby improve cardiac preservation. To inhibit activation, transfected dominant-negative inhibitor MCP-1 (7ND) gene animal model. Methods Results— We used isolated rabbit heart...