A5006614357- Advanced Fiber Laser Technologies
- Laser-Matter Interactions and Applications
- Nuclear Physics and Applications
- Nuclear physics research studies
- Solid State Laser Technologies
- Spectroscopy and Laser Applications
- Atomic and Subatomic Physics Research
- Psoriasis: Treatment and Pathogenesis
- Quantum, superfluid, helium dynamics
- Atomic and Molecular Physics
- Advancements in Photolithography Techniques
- Mass Spectrometry Techniques and Applications
- Advanced NMR Techniques and Applications
- Photonic and Optical Devices
- Dermatology and Skin Diseases
- Photonic Crystal and Fiber Optics
- Particle accelerators and beam dynamics
- X-ray Spectroscopy and Fluorescence Analysis
- Cold Atom Physics and Bose-Einstein Condensates
- Superconducting Materials and Applications
- Particle Accelerators and Free-Electron Lasers
- Advanced Chemical Physics Studies
- Electron and X-Ray Spectroscopy Techniques
- Nuclear reactor physics and engineering
- Autoimmune Bullous Skin Diseases
Max Planck Institute of Quantum Optics
2012-2025
Miyagi Children's Hospital
2020-2025
Tokai University
2004-2024
Matsuyama Shimin Hospital
2024
Toshiba Mitsubishi-Electric Industrial Systems Corporation (Japan)
2018-2023
University of Tsukuba
2008-2022
The University of Tokyo
2009-2018
RIKEN Nishina Center
2010-2018
Interface (United Kingdom)
2018
John Wiley & Sons (United States)
2018
Abstract Generalized pustular psoriasis ( GPP ) is a rare disease characterized by recurrent fever and systemic flushing accompanied extensive sterile pustules. The committee of the guidelines was founded as collaborative project between Japanese Dermatological Association Study Group for Rare Intractable Skin Diseases under Ministry Health, Labour, Welfare Research Project on Overcoming Diseases. aim to provide current information aid in treatment patients with Japan. Its contents include...
Repair of neonatal tetralogy Fallot (TOF) has low mortality. Debate continues regarding the initial management cyanotic or duct-dependent infants with TOF and adverse risk factors. While repair can been performed in these patients, it is associated increased morbidity.We review effectiveness right ventricular outflow tract (RVOT) stenting symptomatic young infant TOF.Clinical, echocardiographic, angiographic haemodynamic data were reviewed for nine patients who underwent 11 RVOT procedures...
We generated a series of harmonics in xenon gas jet inside cavity seeded by pulses from Ti:sapphire mode-locked laser with repetition rate 10.8 MHz. Harmonics up to 19th order at 43 nm were observed plateau the microW power level. An elaborate dispersion compensation scheme and use moderate allowed for this significant improvement output 4 orders magnitude over previous results. With level rate, high-resolution spectroscopy extreme ultraviolet region becomes conceivable. interesting target...
The $1S\text{\ensuremath{-}}2S$ two-photon transition in singly ionized helium is a highly interesting candidate for precision tests of bound-state quantum electrodynamics (QED). With the recent advent extreme ultraviolet frequency combs, coherent quasi-continuous-wave light sources at 61 nm have become available, and spectroscopy this now comes into reach first time. We discuss quantitatively feasibility such an experiment by analyzing excitation ionization rates, propose experimental...
We demonstrate nonlinear pulse compression by multi-pass cell spectral broadening (MPCSB) from 860 fs to 115 with compressed energy of 7.5 µJ, average power 300 W and close diffraction-limited beam quality. The transmission the unit is >90%. results show that this recently introduced scheme for peak powers above threshold catastrophic self-focusing can be scaled smaller energies achieve a larger factor than previously reported. Good homogeneity across profile verified, which distinguishes...
A passive optical resonator is used to enhance the power of a pulsed 78MHz repetition rate Yb laser providing 200fs pulses. We find limitations relating achievable time-averaged and peak power, which we distinguish by varying duration input An intracavity average 18kW generated with close Fourier-limited pulses 10W power. Beyond this level, intensity-related effects lead instabilities, can be removed chirping seed By extending pulse in way 2ps, could obtain 72kW circulating 50W
We demonstrate a fiber Bragg grating (FBG) strain sensor with optical frequency combs. To precisely characterize the response of FBG when is applied, dual-comb spectroscopy used. Highly sensitive enabled measurements resolution 34 nε. The spectral bandwidth measurement exceeds 1 THz. Compared conventional using continuous-wave laser that requires rather slow scanning limited range, dynamic range and multiplexing capability are significantly improved by broadband spectroscopy.
Optical frequency combs are typically generated in the near-infrared wavelength range, where many mode-locked lasers operate. Nonlinear conversion can then be used to extend optical metrology other spectral regions, such as extreme ultraviolet (XUV). High-power at fundamental efficiently drive nonlinear conversions. Low phase noise is an important requirement because process not only multiplies carrier but also fluctuations. In this work, we have developed a low-noise comb centered 1030 nm...
Nanostructures in Al were generated by printing with hard SiC molds. This nano-printing technology replaces the lithography and etching or deposition processes to produce patterns directly metal. Dots, short lines, long lines formed molds electron beam reactive ion etching. High aspect ratio features as small 40 nm depth up 840 patterned By pressing mold onto substrate at room temperature, nanostructures reproduced accurately uniformly Al. Large arrays of down printed similar results for...
A solid-state-laser based single-frequency 589 nm light source that can be easily used in the laboratory is needed for sodium spectroscopy studies and cold atom experiments. This paper shows by using a periodically poled Zn-doped LiNbO(3) ridge waveguide sum-frequency generation, we obtain high conversion efficiency to from two sub-watt 1064 1319 Nd:YAG lasers via simple single pass wavelength process without employing an enhancement cavity. 494 mW at generated achieves overall laser power...
Abstract The clinical use of adalimumab and infliximab, human anti‐tumor necrosis factor (TNF)‐α monoclonal antibodies, for psoriasis began in January 2010. In 2011, ustekinumab, a anti‐interleukin‐12/23p40 (IL‐12/23p40) antibody, was newly approved as the third biologic with an indication psoriasis. While all these biologics are expected to exhibit excellent therapeutic effect contribute improvement quality life patients, drugs require careful safety measures prevent adverse drug reactions,...
Intracavity high harmonic generation was utilized to generate average-power coherent radiation at vacuum ultraviolet (vuv) wavelengths. A ytterbium-doped fiber-laser based master-oscillator power-amplifier (MOPA) system with a 10 MHz repetition frequency developed and used as driving laser for an external cavity. series of odd-order radiations generated extending down ∼ 30 nm (41 eV in photon energy). The 7th centered 149 had average output power up 0.5 mW. In this way, we sub-mW vuv-laser...
Abstract Although many epidemiological surveys for patients with psoriasis have been reported based on individual countries or facilities, there has no study encompassing the major region in Asia. The Asian Society Psoriasis (ASP) conducting an across various and regions to elucidate compare epidemiology of psoriasis. A total 1948 cases were analyzed, 938 from Japan, 530 China, 325 Korea, 141 Chinese Taipei, 14 Thailand, all which enrolled between 2020 2022. In total, male–female ratio was...
The transfer reaction $p{(}^{8}\mathrm{He},d{)}^{7}\mathrm{He}$ has been studied by correlational measurements, and an excited state of ${}^{7}\mathrm{He}$ was observed ( ${E}^{*}\phantom{\rule{0ex}{0ex}}=\phantom{\rule{0ex}{0ex}}2.9\ifmmode\pm\else\textpm\fi{}0.3\mathrm{MeV}$, $\ensuremath{\Gamma}\phantom{\rule{0ex}{0ex}}=\phantom{\rule{0ex}{0ex}}2.2\ifmmode\pm\else\textpm\fi{}0.3\mathrm{MeV}$) which decays mainly into ${3n+}^{4}\mathrm{He}$. Most likely, it a structure with neutron in...
Direct frequency-comb spectroscopy of a single-photon transition ($5{p}^{6}\ensuremath{-}5{p}^{5}6s$) in ${}^{132}\mathrm{Xe}$ is performed with vacuum ultraviolet (vuv) frequency comb at 147 nm. The vuv generated from an Yb-doped fiber laser system repetition rate $\ensuremath{\sim}$79 MHz via high harmonic generation Kr gas jet placed the focus point external enhancement cavity. For Doppler-reduced spectroscopy, collimated atomic beam isotope-selected used as target. Repeated measurements...
Abstract The energy levels of hydrogen-like atoms and ions are accurately described by bound-state quantum electrodynamics (QED). $$\hbox {He}^{+}$$ <mml:math xmlns:mml="http://www.w3.org/1998/Math/MathML"> <mml:msup> <mml:mtext>He</mml:mtext> <mml:mo>+</mml:mo> </mml:msup> </mml:math> have a doubly charged nucleus, which enhances the higher-order QED contributions makes them interesting for precise tests QED. Systematic effects that currently dominate uncertainty in hydrogen spectroscopy,...
A noncollinear resonator with two beams circulating and intersecting in the focus allows resonator-assisted high-harmonic generation of high-power femtosecond pulses efficient geometrical output coupling. However, synchronization alignment is a challenge. We describe design employing wedge mirrors which avoids need for separate beams, providing intrinsic alignment. Transverse shifting fine tuning relative phase pulses, i.e., interference pattern focus. present resonators at MPQ Fraunhofer...