A5020616981- Advanced biosensing and bioanalysis techniques
- Mosquito-borne diseases and control
- Viral Infections and Vectors
- Rabies epidemiology and control
- interferon and immune responses
- Electrochemical sensors and biosensors
- Conducting polymers and applications
- Luminescence Properties of Advanced Materials
- Electrochemical Analysis and Applications
- Viral Infections and Outbreaks Research
- Food composition and properties
- Advanced Photocatalysis Techniques
- Immune Response and Inflammation
- Neuroinflammation and Neurodegeneration Mechanisms
- Animal Virus Infections Studies
- Covalent Organic Framework Applications
- Perovskite Materials and Applications
- Animal Disease Management and Epidemiology
- Gas Sensing Nanomaterials and Sensors
- Polysaccharides Composition and Applications
- Immune Cell Function and Interaction
- Virology and Viral Diseases
- Toxoplasma gondii Research Studies
- Electrocatalysts for Energy Conversion
- Polymer Surface Interaction Studies
Qingdao University
2019-2025
First Affiliated Hospital of Xinjiang Medical University
2015-2025
Xinjiang Medical University
2015-2025
Shanghai Jiao Tong University
2014-2025
Songjiang District Central Hospital
2025
Shandong Maternal and Child Health Hospital
2023-2025
Huazhong Agricultural University
2015-2024
Center of Hubei Cooperative Innovation for Emissions Trading System
2018-2024
Ministry of Science and Technology of the People's Republic of China
2018-2024
Sichuan Agricultural University
2018-2024
Japanese encephalitis is an acute zoonotic, mosquito-borne disease caused by virus (JEV). characterized extensive inflammation in the central nervous system (CNS) and disruption of blood-brain barrier (BBB). However, pathogenic mechanisms contributing to BBB are not known. Here, using a mouse model intravenous JEV infection, we show that titers increased exponentially brain from 2 5 days postinfection. This was accompanied early, dramatic increase level inflammatory cytokines chemokines...
A sensitive and low-fouling aptasensor for alpha-fetoprotein (AFP) was developed based on mixed self-assembled aptamers newly designed zwitterionic peptides, where densely immobilized peptides formed an antifouling layer to resist nonspecific protein adsorption, sparsely attached acted as the recognizing achieve target binding. The obtained biosensing interface responded AFP with a strikingly selective manner, exhibited excellent protein-resistant performance even in complex human serum...
The development of silicon-based anode materials is important for improving the energy density current lithium ion batteries. However, there are still strong demands these with better cycle stability and higher reversible capacity. Here, a kind dual bond restricted MXene-Si-CNT composite enhanced electrochemical performance reported. These bonds have been clearly revealed by an X-ray photoelectron spectroscopy technique also proven theoretical calculations spontaneous reaction values (-0.190...
Warm white LEDs with high color-rendering were achieved using Ca<sub>9</sub>LiY<sub>0.667</sub>(PO<sub>4</sub>)<sub>7</sub>:0.03Eu<sup>2+</sup>,0.10Mn<sup>2+</sup> phosphors.
Japanese encephalitis virus (JEV) can invade the central nervous system and consequently induce neuroinflammation, which is characterized by profound neuronal cell damage accompanied astrogliosis microgliosis. Albeit microRNAs (miRNAs) have emerged as major regulatory noncoding RNAs with effects on inflammatory response, it unknown how astrocytic miRNAs regulate JEV-induced inflammation. Here, we found involvement of miR-19b-3p in regulating responsein vitroandin vivo The data demonstrated...
Amyloid-β oligomer (AβO) is widely regarded as a reliable biomarker for the early diagnosis of Alzheimer's disease (AD). In this study, signal on-off ratiometric electrochemical immunosensor has been developed ultrasensitive detection AβO. To achieve dual-signal strategy, ultrasmall copper sulfide nanoparticle-engineered covalent organic framework hybrid nanocomposites (CuS@COFs) were utilized excellent electrocatalysts toward hydroquinone (HQ) oxidation to produce detectable signals....
Japanese encephalitis is a neuropathological disorder caused by virus (JEV), which characterized severe pathological neuroinflammation and damage to the blood-brain barrier (BBB). Inflammatory cytokines/chemokines can regulate expression of tight junction (TJ) proteins are believed be leading cause BBB disruption, but specific mechanisms remain unclear. IP-10 most abundant chemokine produced in early stage JEV infection, its role disruption unknown. The administration IP-10-neutralizing...
Background. Japanese encephalitis virus (JEV) is a neurotropic flavivirus that causes (JE), which leads to high fatality rates in human. Tumor necrosis factor alpha (TNF-α) key mediates immunopathology the central nervous system (CNS) during JE. Etanercept safe anti-TNF-α drug has been commonly used treatment of various human autoimmune diseases.
The serum level of soluble CD44 is directly associated with several clinicopathological parameters malignant diseases. There a great need for the development an easy and cost-effective detection method both diagnosis treatment cancers. In this work, simple photoelectrochemical (PEC) sensitive serum-soluble proposed based on construction hybrid antifouling coating TiO2 substrate. Hyaluronic acid (HA) poly(ethylene glycol) (PEG) are co-immobilized using biomimetic one-step surface...