The development of protective therapeutic strategies against acute kidney injury associated with suprarenal aneurysms, renal artery occlusive disease, and aortic reconstruction is paramount importance. Adropin a peptide hormone that has been shown to protect vascular endothelial cells reduce oxidative stress, apoptosis, inflammation. Therefore, in addition its metabolic effects, adropin potential as agent ischemia-reperfusion injury. This study aims investigate the effects adropine on (IR)...

. To investigate the impact of garlic extract (GE), which is known for its antioxidant activity, on a testicular torsion/detorsion model in animals and to help understand how prevent both ischemic reperfusion injuries after torsion detorsion. Material methods. Six groups rats (n=7 each group) were used. The control group (Group I) did not receive any treatment. sham II) underwent scrotal incision fixation only. Groups III–VI 720° left 2 h; subsequent detorsion was performed h IV VI Animals V...

The goal of this study is to investigate the association between diagnosis and severity coronary artery disease (CAD) Asprosin level.Patients diagnosed with CAD who underwent conventional angiography for first time were included in present study. patients divided into four groups, each consisting 20 individuals, as medical group, single lesion double multiple lesions group. Serum values Gensini scores groups compared terms compliance.In study, found be significantly higher group than...

Amaç: Çevresel toksinlerden biri olan kadmiyumun dokularda birikimi ciddi toksiteye neden

Possible effects of garlic extract supplementation on blood oxidant/antioxidant status, lipid profile and coronary plaque formation process were investigated in cholesterol-fed rabbits.Thirty-one male rabbits New Zealand strain used. Twenty-two animals given cholesterol for 4 months. Seven them sacrificed to investigate measure parameters. the remaining 15 fed normal laboratory diet others plus additional 3 Blood antioxidant parameters measured histological examination was made.Total, HDL...

The nephrotoxic actions of aluminium (Al) arise from its accumulation in the kidneys, with resultant degeneration renal tubular cells. It has been suggested that Al generates reactive oxygen species cause oxidative deterioration cellular lipids, proteins, and DNA. To test this hypothesis, we have here investigated potential for a protective role α-tocopherol (vitamin E) during short-term exposure rats to Al. was administered intraperitoneally either alone or combination vitamin E at...

In the present study, we investigated effects of simvastatin, a 3-hydroxy-3-methyl-glutaryl coenzyme A reductase inhibitor, on lipid metabolism, peroxidation, antioxidant enzyme activities and ultrastructure diabetic rat lung. Diabetes was induced by single injection streptozotocin (45 mg kg(-1), i.p.). After 8 weeks induction diabetes, some control rats were treated with simvastatin (10 kg(-1) day(-1); orally) for 4 weeks. resulted in significantly high levels blood glucose plasma lipids....

Exposure to tobacco smoke can cause irritation of the conjunctiva. We conducted this study identify effect on rat Animals were divided into experimental and control groups we exposed group smoke. Control rats inhaled only room air. Spectrophotometric analysis smoke-air mixture revealed that many toxic substances present in compound. found very high levels plasma thiocyanate after exposure animals but no increase group. So, data indicates these effectively our method. After 3 months...

In order to investigate the role of nitric oxide (NO) in hypoxic tissue damage newborns, we studied effects systemic administration an inhibitor NO synthase, N(G)-nitro-L-arginine (L-NNA), and precursor for synthesis NO, L-arginine (L-ARG), on biochemical histological changes brain, heart, lung, liver, kidney, intestine, skeletal muscle tissues. Four groups 1-day-old Wistar rat pups were used: control, hypoxic, L-ARG, L-NNA groups. L-ARG 100 mg/kg or 2 was administered as a bolus...

<i>Background:</i> It is a well-established fact that cigarette smoking causes degenerative, inflammatory, and respiratory diseases in humans.Because many factors such as air pollution harsh working conditions can easily be eliminated animal studies, we conducted this study to identify the effect of tobacco on rat trachea. <i>Methods:</i> 24 male Wistar rats were divided randomly into an experimental control group. The group was exposed smoke for 2 h each day over...

The main objective of the present study is to investigate advantages and disadvantages proximal arteriovenous native fistulas. Hemodialysis indispensable for patients with end-stage renal disease. For this purpose, fistulas (AVFs) are used. Among fistulas, distal radiocephalic AVF most preferred. However, brachiocephalic (BCAVF) brachiobasilic basilic vein transposition (basilic fistula [BVTAVF]) can be used a long time in dialysis whose vascular bed depleted.This retrospective 117 AVFs...

: Vascular injuries are commonly seen in both emergency services and forensic medicine practise. They often life-threatening, with high morbidity mortality rates.This study aimed to retrospectively evaluate extremity vascular the associated treatment approaches.After obtaining approval from ethics committee of university, those patients admitted department Adiyaman between 1 February 2013 31 August 2018 were included this study. The patients' data obtained through electronic records system,...

The continuity of arteriovenous fistula (AVF) patency is essential for effective hemodialysis. In the present study, we aimed to investigate relationship between AVF and atherogenic index plasma (AIP) in patients with native proximal upper-extremity AVF.

Nitric oxide (NO) inhibition with NG-nitro-l-arginine methyl ester (l-NAME) in the last trimester of pregnancy caused intrauterine growth retardation and hind-limb disruptions rats. In present study, effect maternal NO (l-NNA) on hypoxic newborn rats was investigated.Timed-pregnant were obtained gestational day 17. Four groups used: control, hypoxic, l-NNA + groups. two groups, (2 mg/kg bolus, i.p.) administered to mothers pups antenatally 3 consecutive days. Hypoxia induced by breathing a...

Amaç: Bu çalışmada amacımız, malignite tanısı ile port kateter implante edilen hastaları retrospektif olarak incelemek ve deneyimlerimizi paylaşmaktır.Gereç Yöntem: Ağustos 2012-Aralık 2018 tarihleri arasında Adıyaman Üniversitesi Tıp Fakültesi Kalp Damar Cerrahisi Kliniğinde malignensi tanısıyla kateteri takılan hastalar çalışmaya dâhil edildi. Toplam 231 hasta (97 kadın, 134 erkek) olarak, hastane veri kayıt sisteminden incelenerek verileri (demografik veri, venöz erişim yolu, teknik...

Background/Aim: Cuffed-tunneled catheter patients encounter various problems during their catheterization period. Early detection and resolution of these prolong the life catheter. The purpose present study was to investigate solution methods cuffed-tunneled catheters in hemodialysis use light our experience literature. Methods: designed as a retrospective cohort study. Twenty-four months patient data who had diagnosis renal failure received between January 2013 June 21 Department...

Thrombotic complications increase in novel coronavirus disease 2019 (COVID-19) patients.Most of these are associated with venous thromboembolism and pulmonary embolism; arterial thrombosis is rare.Usually, affects peripheral arteries.The involvement large vessels, such as aorta, rare the literature.Major artery manifests different additional complications.Contrast-enhanced abdominal computed tomography angiography (CTA) was performed on a patient, who followed-up COVID-19 due to...

Aim: In patients whose life is dependent on hemodialysis, the most suitable vascular access routes are arteriovenous fistulas made with native vessels. However, in natural vessels depleted, or not suitable, can be opened artificial grafts. Our aim to examine synthetic grafts hemodialysis who do have upper extremity and share our results.Methods: Patients underwent opening of an fistula a graft extremities Adıyaman University Faculty Medicine, Cardiovascular Surgery Clinic between December...