In this study, total cytoplasmic (Cu,Zn-SOD) and mitochondrial (Mn-SOD) superoxide dismutase activities were measured in sera pleural fluids from patients with squamous cell carcinoma of the lung. The results compared those control subjects tuberculosis chronic heart failure. Serum found higher all patient groups to group. Highest values however correlation analysis, meaningful intra- inter-correlations established between enzyme samples. Results suggest that high serum fluid SOD are not...

The objective of this study is to develop a chitosan gel formulation containing liposomes loaded with epidermal growth factor (EGF) and evaluate their effects on the healing second-degree burn wounds in rats by immunohistochemical, histochemical histological methods. EGF-containing multilamellar which were carried gel, EGF EGF-loaded liposome formulations prepared. vivo experiments performed female Sprague Dawley rats. Second-degree standard formed 10 µg/ml 2% EGF-chitosan applied daily...

Enzymatic antioxidant defense system and potential (AOP) were studied in kidney tissue from rabbits treated with cyclosporine (CsA, 25 mg/kg/day), vitamins (E, 100 mg/kg/day plus C, 200 mg/ kg/day), CsA vitamins, control animals. Although no change was observed superoxide dismutase (SOD) activity, glutathione peroxidase (GSH-Px) catalase (CAT) activities found decreased exposed to for 10 days compared tissue. The level of thiobarbituric acid-reagent substances (TBARS) higher lower the...

Research on new serum parameters in bipolar disorder (BD) and schizophrenia is crucial for early diagnosis understanding of disease pathophysiology. The arginine metabolic pathway has been found to be associated with several neuropsychiatric disorders recent years. This study aims investigate the role markers involved different steps BD schizophrenia. Sixty healthy volunteers, sixty patients were included study. We analysed ornithine decarboxylase (ODC), (ADC) agmatinase levels using...

In this study, the activities of major enzymes participating in free radical metabolism (xanthine oxidase, XO; Cu,Zn and Mn superoxide dismutases, SOD; glutathione peroxidase, GSH-Px; catalase, CAT) were measured kidney tissues from guinea pigs treated with gentamicin alone (200 mg/kg/day), plus vitamin C (600 E (400 vitamins together for 10 days, animals physiological saline solution during period. We found no significant differences between control groups respect to XO Cu,Zn-SOD...

The present study reviews 215 male patients suffering high velocity-high energy injuries of the lower leg or foot caused by war weapons such as missiles, gunshots, and land mines. They were treated in Department Plastic Reconstructive Surgery at Gulhane Military Medical Academy (Ankara, Turkey) between November 1993-January 2001. Severe soft-tissue defects requiring flap coverage associated open bone fractures that 7-21 days (mean, 9.6 days) after injury included study. Twenty-three 226...

This study aims to investigate the role of oxidants in cisplatin-induced nephrotoxicity. Cisplatin was administered intraperitoneally (i.p.) a single dose (5 mg/kg) and guinea pigs were killed either after 24 h or 7 days. The same experiment performed using animals treated with vitamins C E combination natural antioxidant extract (SARMEX). kidneys then removed be used analyses. Blood samples also obtained from routine biochemical assays. Twenty-four hours treatment there significant decrease...

Purpose: The objective of this article is to present the long-term outcomes ultra-thin polyethylene implants used for orbital floor reconstruction in facial trauma patients. Materials and Methods: From 1998 2004, 38 patients underwent with porous a mean follow-up 4 years. A subciliary incision preexisting wounds or scars were used. boundaries maxillofacial injury volumes both orbits assessed by computed tomography images obtained pre- postoperatively. In all patients, various sizes...

Microsurgical operations of the hand are common procedures reconstructive surgeons. Sympathetic blockade vessels provides increased blood flow to injured extremity, which increases success rate surgery. Moreover, postoperative pain management can be performed with continuous nerves. In this article, effect brachial plexus on patients who underwent upper extremity microsurgical operation was evaluated.A total 16 were operated either for replantation or toe-to-hand transfer. The first group (n...

Background The purpose of this study was to investigate the effects bone marrow–derived stem cells on consolidation period by using a new biomechanical testing method sheep mandible model. Methods Eight underwent bilateral mandibular osteotomies. After latency period, distraction activated. Mesenchymal were transplanted into gap left distracted callus first day period. then randomly divided 2 groups (group A = 4, group B 4). Group and animals killed third sixth weeks consolidation,...

Activities of adenosine deaminase (ADA), 5'nucleotidase (5'NT), xanthine oxidase (XO), superoxide dismutase (SOD), glutathione peroxidase (GSH-Px), and catalase (CAT) levels thiobarbituric acid reagent substances (TBARS) were measured in 10 cancerous noncancerous human prostate tissues. Decreased activities DNA turnover enzymes (ADA 5'NT), increased GSH-Px CAT, unchanged SOD XO observed tissues compared with those ones. TBARS found to be higher than In correlation analysis, mostly positive...

Antioxidant defense capacity was investigated in myocardial tissue from guinea pigs treated with 5-fluorouracil (5-FU) at a dose of 400 mg/kg/d daily for 5 d administered intraperitonally. Treatment 5-FU lowered the activities cardiac superoxide dismutase (SOD) and glutathione peroxidase (GSH-Px) accompanied by higher catalase (CAT) activity. Further, antioxidant potential (AOP) values were lower but oxidation resistance (OR) malondialdehyde (MDA) levels 5-FU-treated tissue. With regard to...

Volatile anesthetics (VAs) have been shown to enhance myocardial recovery during reperfusion, the mechanism of which has not clarified yet. It supposed that this effect VAs may appear through antioxidative mechanisms.Thirty guinea pigs were used in study. There three groups with 10 animals each: I - control, II isoflurane+oxygen and III oxygen. Isoflurane (2.0% v/v) oxygen (100%) mixture was given via a face mask group at rate 21 per min for 30 day consecutive days. In group, alone under...

Possible effects of garlic extract supplementation on blood oxidant/antioxidant status, lipid profile and coronary plaque formation process were investigated in cholesterol-fed rabbits.Thirty-one male rabbits New Zealand strain used. Twenty-two animals given cholesterol for 4 months. Seven them sacrificed to investigate measure parameters. the remaining 15 fed normal laboratory diet others plus additional 3 Blood antioxidant parameters measured histological examination was made.Total, HDL...