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Silas D. Leitão da Graça

ORCID: 0000-0001-9708-7680
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About
Contact & Profiles
A5081495059
Research Areas
  • Adipokines, Inflammation, and Metabolic Diseases
  • Cancer, Lipids, and Metabolism
  • Atherosclerosis and Cardiovascular Diseases
  • Peroxisome Proliferator-Activated Receptors

Université de Montréal
 2019-2020

 Atheroprotective and atheroregressive potential of azapeptide derivatives of GHRP-6 as selective CD36 ligands in apolipoprotein E-deficient mice
OPENALEX - Publications 
Geneviève Frégeau Roger Sarduy Hanan Elimam Cloé L. Esposito Katia Mellal and 9 more Liliane Ménard Silas D. Leitão da Graça Caroline Proulx Jinqiang Zhang Maria Febbraio Yosdel Soto William D. Lubell Huy Ong Sylvie Marleau

Background and aimsScavenger receptor class B member 3, also known as cluster of differentiation-36 (CD36) receptor, is involved in the uptake accumulation modified lipoprotein macrophages, driving atherosclerosis progression. Azapeptide analogs growth hormone-releasing peptide-6 (GHRP-6) have been developed selective CD36 ligands evaluated for their anti-atherosclerotic properties apoe−/− mice.MethodsFrom 4 to 19 weeks age, male mice were fed a high fat cholesterol (HFHC) diet, then...

10.1016/j.atherosclerosis.2020.06.010 article EN cc-by-nc-nd Atherosclerosis 2020-07-06
 Atheroregressive Potential Of Azapeptides Analogues Of Ghrp-6 As Selective Cd36 Ligands In Apolipoprotein E-Deficient Mice
OPENALEX - Publications 
Geneviève Frégeau Roger Sarduy Liliane Ménard Hanan Elimam Silas D. Leitão da Graça and 4 more José Elías García William D. Lubell Huy Ong Sylvie Marleau

10.1016/j.atherosclerosis.2019.06.056 article EN Atherosclerosis 2019-08-01
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