A5047440094- Tuberculosis Research and Epidemiology
- Diagnosis and treatment of tuberculosis
- Mycobacterium research and diagnosis
- Infectious Diseases and Tuberculosis
- Pharmacological Effects of Natural Compounds
- Pneumonia and Respiratory Infections
- Pneumocystis jirovecii pneumonia detection and treatment
- Respiratory and Cough-Related Research
- Immune cells in cancer
- Phagocytosis and Immune Regulation
- Respiratory viral infections research
- Insect and Pesticide Research
- Pediatric health and respiratory diseases
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- Viral Infections and Vectors
- Tryptophan and brain disorders
- Intestinal Malrotation and Obstruction Disorders
- HIV/AIDS Research and Interventions
- Chemical Reactions and Isotopes
- Drug-Induced Hepatotoxicity and Protection
- Healthcare Systems and Public Health
- Plant-based Medicinal Research
- Heart Rate Variability and Autonomic Control
- Pharmacogenetics and Drug Metabolism
- Bipolar Disorder and Treatment
Novosibirsk State Medical University
2013-2025
Ministry of Health of the Russian Federation
2025
Novosibirsk Tuberculosis Research Institute
2013-2022
Federal Agency for Health and Social Development
2011
Gastrointestinal tract (GIT) diseases are widespread among the population, including rural residents. Long-term course without sufficient therapy can lead to protein-energy and immunological deficiency, making patients vulnerable tuberculosis infection. Objective. To predict risk of developing pulmonary (TB) in with comorbid gastrointestinal pathology living areas. Materials methods. The reOR=10.63trospective study included 268 newly diagnosed TB. In 48 cases, a combination TB chronic was...
Введение. При нейроинфекциях вследствие бактериемии или вирусемии возникает генерализованный васкулит, в том числе и церебральных сосудов, что обусловливает развитие дисфункции эндотелия. Это способствует возникновению тромбоза нарушению сосудистой регуляции, стимулирует нейровоспаление за счет увеличения секреции провоспалительных цитокинов из иммунных нейрональных клеток, таких как микроглия астроциты. Предполагается, активация микроглии играет важную роль гибели клеток высвобождения...
The article describes the clinical case of effective treatment tuberculosis patient suffering from extensive drug resistance M. tuberculosis. It modern approaches to diagnostics and multiple resistant tuberculosis, best chemotherapy regimen including new anti-tuberculosis drugs, supplemented by valve bronchial block, demonstrates feasibility integral approach
The objective : to evaluate the efficacy and safety of various anti-tuberculosis therapy regimens for multiple drug resistant (MDR) extensive pulmonary tuberculosis in intensive phase treatment lasting 8 months minimum. Subjects Methods . A single-center cohort prospective-retrospective clinical study was conducted, which included 166 patients aged 18 70 years with active proven MDR Mycobacterium tuberculosis, who received chemotherapy according IV V. regimen Group I (n = 96) modern drugs...
The difficulties in the interpretation of identified during bronchoscopy local bronchi alterations patients with pulmonary tuberculosis make this problem current interest. comprehensive survey 287 revealed specific origin bronchial tree 50% destruc-tive and bacterioexcretion
The article presents medical and social parameters of TB/HIV c o-i nfection in the patients living Novosibirsk Region city Novosibirsk. It is necessary to find some ways enhance poor patients' adherence examinations treatment on inte r-d isciplinary level.
The article presents the analysis of outcomes short course treatment tuberculosis patients with multiple drug resistance (MDR TB), which was twice shorter compared to standard (9-12 months versus 20-14 months). efficiency short-course and did not differ significantly in new MDR TB cases those previously who had limited tuberculous lesions received no therapy second line drugs past (69.2% 68.2%), while default rate less (13.5% 27%, p = 0.03). Economic treatment: costs for were 3 times lower one.
112 tuberculosis patients with burdened allergic history were examined the purpose to study clinical and laboratory manifestations of drug-induced nephropathy, they made main group 157 without allergy control group. Drug-induced renal lesion in multiple allergies can be manifested various ways: from microhematuria, minor eosinophilia cutaneous syndrome major disorders nitrogenous excretion, filtration resorption function kidneys leading development acute some cases chronic failure....
Введение. Наиболее частыми формами инфекций нижних дыхательных путей в практике врача являются острый бронхит и внебольничная пневмония. Врачу приходится принимать решение о тактике ведения таких пациентов с учетом клинической картины результатов обследования. Внебольничная пневмония является распространенным потенциально угрожающим жизни заболеванием органов дыхания. Острота проблемы состоит том, что периоды эпидемий гриппа или других респираторных вирусных активируется Streptococcus...
Introduction. Over the past 10 years, there has been an increase in HIV-1 resistance to antiretroviral drugs worldwide. HIV infection patients with low adherence therapy (ART) are most often at risk of developing acquired resistance. The identification key factors affecting degree will allow timely detection a high poor ART and treatment defaulting, develop individual management tactics for such reduce development. Aim. To study influencing virological failure effect on first-line drugs....
Objective. To study the contribution of radiology methods to diagnostics inflammatory changes in bronchial tree pulmonary TB patients. Materials and methods. We carried out a retrospective cohort study. It included main group patients with local diagnosed by tracheobronchoscopy (461 patients) comparison without tracheobronchial (496 patients). assessed matching between radiological endoscopic signs lesion tree. Results. established direct correlation severity revealed endoscopy number...
Prevention of both chronic non-communicable and infectious diseases is the basis modern healthcare. The danger to public health among (NCDs) is, first all, cardiovascular (CVD), occupying a leading place causes death in young middle-aged people. Among same age category pulmonary tuberculosis (TB). At time, quality availability medical care for rural residents are worse position compared urban residents. Determination risk factors people with pathology necessary reduce morbidity, disability...
Iron deficiency anemia (IDA) is the most common type of anemic disorder, accounting for 41.5% cases. According to WHO, clear lack iron fixed at 30% world’s population, but 2 times more likely observe a latent deficiency. The article discusses diagnosis in practice gastroenterologist. A list diseases gastrointestinal tract and algorithms detecting them are presented.
Based on literature data, the review presents current information a wide range of clinical manifestations Q fever, as well laboratory methods for diagnosing disease. fever is zoonotic disease with variety transmission routes its pathogen – Coxiella burnetii. The main carriers coxiellas are ixodid ticks; in anthropogenic foci their hosts domestic and livestock animals. Novosibirsk region were found back 90s last century, however, diagnostics was not performed over past two decades. Due to...
Abdominal tuberculosis is a specific tuberculous lesion of the abdominal organs. In children, mostly secondary, occurring mainly in form mesadenitis and intestinal tuberculosis. most cases (63–96%), process localized ileocecal valve. The article presents case untimely diagnosed with lymph node lesions peritoneum intestines child intrathoracic all groups during densification calcification onset. examination (computed tomography) revealed valve, while histology biopsy material taken...
The article presents the analysis of multiple drug resistant tuberculosis (MDR TB) prevalence among new and previously treated cases in Kyrgyz Republic 2016. part MDR TB makes 21.9%, relapses – 49.2%, 64%. 52.2% are susceptible to anti-tuberculosis drugs, as 28.1% 17.8% patients.