Toshiya Yamaguchi

ORCID: 0000-0001-9719-7812
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About
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Research Areas
  • Reproductive biology and impacts on aquatic species
  • Aquaculture Nutrition and Growth
  • Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities
  • Animal Genetics and Reproduction
  • Aquaculture disease management and microbiota
  • Cardiac, Anesthesia and Surgical Outcomes
  • Pericarditis and Cardiac Tamponade
  • Organ Transplantation Techniques and Outcomes
  • Tuberculosis Research and Epidemiology
  • Cerebrovascular and Carotid Artery Diseases
  • Effects and risks of endocrine disrupting chemicals
  • Fish Ecology and Management Studies
  • Health, Nursing, Elderly Care
  • Psychology and Mental Health
  • Cholangiocarcinoma and Gallbladder Cancer Studies
  • Physiological and biochemical adaptations
  • Sports Science and Education
  • Chemotherapy-induced cardiotoxicity and mitigation
  • Palliative and Oncologic Care
  • Thermal Regulation in Medicine
  • Robotic Locomotion and Control
  • Autoimmune and Inflammatory Disorders
  • Nanomaterials and Printing Technologies
  • Sepsis Diagnosis and Treatment
  • Heme Oxygenase-1 and Carbon Monoxide

Japan Fisheries Research and Education Agency
2011-2023

University of Tsukuba
2023

Nippon Kayaku (Japan)
2013

Tohoku University
2012

Shizuoka University
2011

Kumamoto University
1988-2010

Polytec (Germany)
2008

Tokai University
1998

In vertebrates, sex is normally determined by genotype. However, in poikilothermal including reptiles, amphibians, and fishes, determination greatly influenced environmental factors, such as temperature. Little known about the molecular mechanisms underlying these species. The Japanese flounder (Paralichthys olivaceus) a teleost fish with an XX/XY system. XX can be induced to develop into predominantly either phenotypic females or males, rearing at 18 27 C, respectively, during...

10.1210/en.2010-0228 article EN Endocrinology 2010-06-09

Abstract In poikilothermic vertebrates, sex determination is sometimes influenced by environmental factors such as temperature. However, little known about the molecular mechanisms underlying determination. The medaka ( Oryzias latipes ) a teleost fish with an XX/XY system. Recently, it was reported that XX can be sex‐reversed into phenotypic males high water temperature (HT; 32–34°C) treatment during differentiation period. Here we report cortisol caused female‐to‐male reversal and...

10.1002/mrd.21203 article EN Molecular Reproduction and Development 2010-05-25

The maturation of fish oocytes is a well-characterized system induced by progestins via non-genomic actions. In previous study, we demonstrated that diethylstilbestrol (DES), non-steroidal estrogen, induces oocyte the membrane progestin receptor (mPR). Here, attempted to evaluate effect DES as an environmental endocrine disrupting chemical (EDC) upon using live zebrafish. triggered within several hours in vivo when administrated directly into surrounding water. natural teleost...

10.1371/journal.pone.0025206 article EN cc-by PLoS ONE 2011-09-28

Japanese flounder ( Paralichthys olivaceus ) is an important marine fish species of both fisheries and aquaculture in Northeast Asia. The commercial interest for all-female progenies due to several sex-related traits has prompted basic research on the mechanisms sex determination this species. By conducting a linkage analysis sex-determining locus, we initially identified 12 microsatellite markers linked 11 scaffolds, whose localization was restricted specific region group 9. Sequence 181...

10.3389/fgene.2022.1007548 article EN cc-by Frontiers in Genetics 2022-09-16

The anti-Müllerian hormone (Amh) is a protein belonging to the TGF-β superfamily, function of which has been considered important for male sex differentiation in vertebrates. Japanese flounder (Paralichthys olivaceus) teleost fish that an XX/XY determination system and temperature-dependent determination. In this species, amh expression up-regulated genetic males temperature-induced masculinization during period. However, best our knowledge, no reports on Amh receptor (Amhr2) have published,...

10.3390/ijms24032480 article EN International Journal of Molecular Sciences 2023-01-27

In bluefin tuna aquaculture, high mortalities of hatchery-reared juveniles occur in sea cages owing to wall collisions that are caused by high-speed swimming panic due changes illuminance. Here, we report targeted gene mutagenesis the ryanodine receptor (RyR1b), which allows sarcoplasmic reticulum release Ca2+ fast skeletal muscle, using highly active Platinum TALENs slow behaviour response external stimuli Pacific (PBT) larvae. This characteristic would be a useful trait prevent aquaculture...

10.1038/s41598-019-50418-3 article EN cc-by Scientific Reports 2019-09-25

We conducted an in vivo study to evaluate the anticancer effect and toxicity of fine-powder cisplatin suspended lipiodol (fCDDP/LPD suspension) after a single administration three different doses rats via intrahepatic artery transplantation rat ascites hepatoma cells. The fCDDP/LPD suspension was also assessed same protocol noncancer-bearing observed toxicologic changes were compared among groups administered saline (Sal), aqueous solution fCDDP (fCDDP/Sal solution), LPD alone. In parallel...

10.5582/ddt.2013.v7.5.201 article EN Drug Discoveries & Therapeutics 2013-01-01

In this study, a VR system to train natural navigation skills, one of the techniques scuba diving was developed and validated. The person experiencing wears an HMD tries swim through ocean created in virtual space, relying on underwater landmarks follow accurate route. To evaluate usefulness for training, scores taken measure accuracy trainees' swimming route compared how much value changed between first second training sessions. addition, trainees were also asked answer questionnaires from...

10.1109/nicoint59725.2023.00020 article EN 2023-06-01

Download This Paper Open PDF in Browser Add to My Library Share: Permalink Using these links will ensure access this page indefinitely Copy URL DOI

10.2139/ssrn.4776690 preprint EN 2024-01-01

In this study, it is discussed how the cutting conditions for drilling deep holes in austenite stainless steel affect machining accuracy of hole straightness and temperature rise. As a result, possible to reduce thrust force make time short by combination step-feed amount feed rate. By changing drill incremental step from length long length, was improved. It also found that rise around 10 K regardless speed when small μm given.

10.4028/www.scientific.net/amr.806.162 article EN Advanced materials research 2015-11-01

The purpose of this research is to develop dinosaur type biped robot, realize walking and running motion. If the size robot becomes small, it necessary shorten sampling time. In controlled by using FPGA that operates more high-speed than CPU.

10.1299/jsmermd.2008._1a1-e08_1 article EN The Proceedings of JSME annual Conference on Robotics and Mechatronics (Robomec) 2008-01-01
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