A5043872312- Respiratory and Cough-Related Research
- Phonocardiography and Auscultation Techniques
- Solid State Laser Technologies
- Crystal Structures and Properties
- Photorefractive and Nonlinear Optics
- Asthma and respiratory diseases
- Respiratory viral infections research
- Neonatal Respiratory Health Research
- Infection Control and Ventilation
- COVID-19 epidemiological studies
- Birth, Development, and Health
- Music Therapy and Health
- Ear Surgery and Otitis Media
- Nutritional Studies and Diet
- Prenatal Substance Exposure Effects
- Allergic Rhinitis and Sensitization
- Health disparities and outcomes
- Mycobacterium research and diagnosis
- Advanced DC-DC Converters
- Tracheal and airway disorders
- Air Quality and Health Impacts
- Alcohol Consumption and Health Effects
- Hemoglobin structure and function
- Luminescence Properties of Advanced Materials
- Olfactory and Sensory Function Studies
Tokai University
2016-2025
Shonan University of Medical Sciences
2025
Tokyo Metropolitan Children's Medical Center
2022
Advanced Institute of Industrial Technology
2022
Juntendo University
1983-2019
Ishikiriseiki Hospital
2014-2019
Tokyo Metropolitan Geriatric Hospital
2019
University of Tokyo Hospital
2018
Kōchi University
2017
Kyoto University
2011-2014
We report on the growth of GdCa 4 O(BO 3 ) (GdCOB) and YCa (YCOB) crystals their characterization as new nonlinear optical materials. The with good quality were grown by Czochralski method. YCOB, characteristics which has not previously been reported to our knowledge, a larger temperature acceptance bandwidth than that GdCOB, third harmonic generation Nd:YAG laser in this crystal was demonstrated.
Rationale: Respiratory syncytial virus (RSV) induces not only infantile recurrent wheezing but also potentially atopic asthma.Objectives: To test the effect of RSV infection on development subsequent asthma, we evaluated whether palivizumab, an anti-RSV monoclonal antibody, by preventing severe disease in first year life, could impact and asthma at 6 years age.Methods: During 2007 to 2008 season, decision administer palivizumab was made based standard medical practice observational...
To assess the relationship between alcohol intake and mortality in a cohort of women aged 70 older to explore level use changes physical mental health-related quality life.National longitudinal surveys from 1996 2002.Community based.A national random sample 12,432 Australian 75 at baseline.Alcohol consumption was factor interest, main outcome measures were survival life, with adjustment for potential confounders.Women who did not consume or drank rarely more likely die (nondrinkers' hazard...
A nonlinear optical crystal YCa(4)O(BO(3))(3) (YCOB) is phase matchable for third-harmonic generation (THG) of a Nd:YAG laser by type I mixing between 1.064 and 0.532mum . By partial substitution Gd Y in YCOB, solid solution Gd(x)Y(1-x)Ca(4)O(BO(3))(3) gradually changes the phase-matching angles THG to (theta, ø)=(90( degrees ), 90 ( )) We present properties noncritically phase-matched Gd(x) Y(1-x)Ca(4)O(BO(3))(3) (x=0.28)
OBJECTIVES: Our aim is to compare the efficacy and safety of high-flow nasal cannula (HFNC) against those continuous positive airway pressure (NCPAP) or intermittent positive-pressure ventilation (NIPPV) after extubation in preterm infants. METHODS: This prospective, randomized, noninferiority trial was conducted 6 tertiary NICUs. Infants born at <34 weeks who needed noninvasive were enrolled. We randomly assigned infants an HFNC group when used NCPAP/NIPPV NCPAP NIPPV used. The...
Biodegradable hydrogels with three different water contents were prepared through the glutaraldehyde crosslinking of gelatin an isoelectric point 5.0 under varied reaction conditions. The objective this study is to investigate effect time period basic fibroblast growth factor (bFGF) release that modified by hydrogel content, on bone regeneration. A fracture was at femur mice, while incorporating bFGF or solution applied site. exhibited significantly stronger regeneration than solution,...
The aim of the present study was to evaluate validity potential prognostic parameters clear cell renal carcinoma (ccRCC) recommended by 2012 International Society Urological Pathology (ISUP) Consensus Conference in Japanese population. We reviewed 406 patients with localized or locally advanced ccRCC who underwent curative surgery during 2004-2014 at Tokai University Hospital (Isehara, Japan) and were followed up for >2 years after surgery. A single pathologist all histological slides....
Abstract Background Respiratory syncytial virus (RSV) causes not only infantile recurrent wheezing but also the development of asthma. To investigate whether palivizumab, an anti‐RSV monoclonal antibody, prophylaxis given to preterm infants during first RSV season reduces incidence subsequent and/or asthma, at 10 years age. Methods We conducted observational prospective multicenter (52 registered hospitals in Japan) case‐control study with a gestational age between 33 and 35 weeks followed...
Lung sound analysis parameters have been reported to be useful biomarkers for evaluating airway condition. We developed an automatic lung software program infants and children based on spectral curves of frequency power by leveraging machine learning (ML) technology. To put this into clinical practice, in Study 1, the reliability reproducibility using data from younger were examined. In 2, relationship between respiratory flow (L/s) was evaluated older children. 3, we conducted a survey...
In recent years, with the advent of artificial intelligence, clear progress has been made in clinical application lung sound analysis techniques. Using a new software program to analyze pediatric sounds using machine learning (ML), we conducted survey study 139 healthy 3-year-old children. All cases were surveyed ATS-DLD questionnaire, which mainly included items related history wheezing, diagnosis asthma, and respiratory syncytial virus (RSV) infection, allergies environment. The...
Abstract Background Discussions regarding the treatment of acute bronchiolitis are ongoing. In this study, we investigated effects bronchodilators in infants with viral using a lung sound analysis. Methods Subjects were hospitalized children diagnosed who received inhaled short‐acting beta 2‐agonist (SABA). Lung sounds collected before and after SABA inhalation, imaged quantified dedicated analysis system to objectively evaluate SABA. Furthermore, influence child's clinical symptoms...
A new lung sound analysis software program has been developed. It can automatically select a typical spectrogram and calculate parameters using machine learning programs. This study aimed to clarify characteristics in early infants this program. Using the program, of sounds healthy 1- 4-month-old were examined. The assessed supine position for 1-month-old both sitting positions infants. We compared infant with those 3-year-old children. (n = 58) affected by gender, height, birth weight....
A clinical picture of patients with acute respiratory distress syndrome (ARDS) induced by highly pathogenic avian influenza (H5N1) has been reported. We reviewed 37 sets data for pediatric ARDS at the National Hospital Pediatrics (Hanoi, Vietnam); 12 H5N1-positive and 25 H5N1-negative were enrolled. The had a mortality rate similar to that patients. However, normal ventilation capacity time hospital admission, then rapidly proceeded severe failure. survival probability days until final...
Nasal mucosa is a subject of surgical operation for patients with nasal disorders. However, our knowledge about the regeneration after such mechanical injury still limited. In this study we investigated recovery or regenerative process in rabbits on basis ultrastructural as well functional observations. Complete was obtained 5 days if basal cells and basement membrane were intact. When total layer injured mechanically, stratified epithelium covered defect 1 week, new ciliated appeared 3...
Lipopolysaccharide (10 micrograms/mL) derived from Klebsiella pneumoniae was injected into the middle ear of guinea pigs. The animals were killed painlessly on days 1, 3, and 7 after inoculation, mucosal samples two sites within tympanic cavity, close to orifice distal orifice, examined for ciliary activity epithelial morphology. At day 1 3 serous effusion observed deterioration morphologic changes observed. No recognized at 7, when in mucosa still diminished that proximal had recovered a...
Abstract Background Acute respiratory distress syndrome (ARDS) is one of the most lethal diseases encountered in pediatric intensive care unit (PICU). The etiological pathogens and prognostic factors severe ARDS pulmonary origin children with virus infections were prospectively investigated. Methods Enrolled fulfilled following criteria: (1) PICU admission; (2) age 1 month to 16 years; (3) diagnosis infectious pneumonia infection; (4) development within 72 h after admission. Pathogens...
Abstract Liposome‐encapsulated hemoglobin (LEH) was proven to be protective in cerebral ischemia/reperfusion injury. The present study evaluated LEH a rat model of permanent middle artery (MCA) occlusion clarify its effect during ischemia and reperfusion. Five minutes after thread the MCA, rats were infused with 10 mL/kg (LEH, n = 13), compared normal controls ( 11). Additional animals received same MCA no treatment (CT, 11), saline (saline, 10), empty liposome solution (EL, or washed red...