Ausama A. Malik

ORCID: 0000-0001-9738-8651
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About
Contact & Profiles
Research Areas
  • Airway Management and Intubation Techniques
  • Probiotics and Fermented Foods
  • Clinical Nutrition and Gastroenterology
  • T-cell and B-cell Immunology
  • Infant Nutrition and Health
  • Tracheal and airway disorders
  • Gut microbiota and health
  • Mycobacterium research and diagnosis
  • Intestinal Malrotation and Obstruction Disorders
  • IL-33, ST2, and ILC Pathways
  • Immune Cell Function and Interaction
  • Central Venous Catheters and Hemodialysis

University of Malaya
2015-2016

Significance We demonstrate, to our knowledge for the first time, that bacterial biofilms are associated with colorectal cancers, one of leading malignancies in United States and abroad. Colon biofilms, dense communities bacteria encased a likely complex matrix contact colon epithelial cells, nearly universal on right tumors. Most remarkably, biofilm presence correlates tissue invasion changes biology enhanced cellular proliferation, basic feature oncogenic transformation occurring even...

10.1073/pnas.1406199111 article EN Proceedings of the National Academy of Sciences 2014-12-08

IL17-producing Th17 cells, generated through a STAT3-dependent mechanism, have been shown to promote carcinogenesis in many systems, including microbe-driven colon cancer. Additional sources of IL17, such as γδ T become available under inflammatory conditions, but their contributions cancer development are unclear. In this study, we modeled Th17-driven tumorigenesis by colonizing Min(Ap) (c+/-) mice with the human gut bacterium, enterotoxigenic Bacteroides fragilis (ETBF), investigate link...

10.1158/0008-5472.can-15-0749 article EN Cancer Research 2016-02-16

We describe extremely rare cases of vocal cord palsy following surgical insertion a chemo port. Our cohort consisted patients with cancer who developed hoarseness immediately after central venous line placement for the administration chemotherapy, confirmed flexible laryngoscopy. Given timing, appears to be most likely cause.

10.1002/lary.25422 article EN The Laryngoscope 2015-06-24
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