A5056201641- Head and Neck Surgical Oncology
- Sinusitis and nasal conditions
- Ear Surgery and Otitis Media
- Meningioma and schwannoma management
- Oral and Maxillofacial Pathology
- Vestibular and auditory disorders
- Ear and Head Tumors
- Hearing, Cochlea, Tinnitus, Genetics
- Nasal Surgery and Airway Studies
- Salivary Gland Tumors Diagnosis and Treatment
- Tracheal and airway disorders
- Head and Neck Cancer Studies
- Pituitary Gland Disorders and Treatments
- Hearing Loss and Rehabilitation
- Allergic Rhinitis and Sensitization
- Otolaryngology and Infectious Diseases
- Olfactory and Sensory Function Studies
- Tumors and Oncological Cases
- Congenital Ear and Nasal Anomalies
- Head and Neck Anomalies
- Infectious Diseases and Tuberculosis
- Voice and Speech Disorders
- Airway Management and Intubation Techniques
- Teratomas and Epidermoid Cysts
- Asthma and respiratory diseases
University of Malaya
2016-2025
Ministry of Health
2024
Wave Life Sciences (United States)
2024
University of Kuala Lumpur
2009-2023
University Malaya Medical Centre
2011-2023
Laryngograph (United Kingdom)
2016
University of Aberdeen
2015-2016
Queen Elizabeth Hospital
2016
Council of Economic Advisers
2015
Jubilee Mission Medical College and Research Institute
2012
Purpose: Across Hong Kong, Malaysia, the Philippines, Singapore, Thailand and Vietnam, (referred to as Asia) approximately 30-53 million individuals of 151 employed suffer from allergic rhinitis (AR) urticaria.It is estimated that 90% patients with these conditions are insufficiently treated, impacting socioeconomic burden in terms absence work decreased productivity.This study aims estimate allergies Asia cost savings their adequate management can provide.Due limited availability regional...
Orbital cavernous hemangiomas (OCH) are the most common adult orbital tumor and represent an ideal index lesion for endonasal surgery. In order to standardize outcomes reporting, anatomic-based staging system was developed.An international, multidisciplinary panel of 23 experts in surgery formed. A modified Delphi method used develop hemangioma exclusively resection (CHEER) with a total 2 rounds being completed.Tumors medial plane along long axis optic nerve may be considered amenable...
Advancements in endoscopic sinus and skull base surgery created a need for standardized terminology to describe sphenoid surgery. Although classification systems exist other sinuses, one is lacking. Developing such system would standardize procedure descriptions promote common language among surgeons. This study aimed develop new Consensus on novel by running the Delphi with 16 rhinology experts from around world. Four rounds were required reach consensus all stages of classification. The...
Background The Allergies in Asia–Pacific Survey describes the symptoms, impact, and treatment of allergic rhinitis (AR) across Australia, China, Hong Kong, Malaysia, Singapore, Taiwan, Vietnam, Philippines. was undertaken to further clarify prevalence physician-diagnosed nasal allergies (NAs), impact on quality-of-life (QOL), existing paradigms gaps, NA medications currently used treatment. Methods Thirty-three thousand three hundred seventy-eight households were screened for individuals, ≥...
Background Surgical navigation systems have been used increasingly in guiding complex ear, nose, and throat surgery. Although these are helpful, they only beneficial intraoperatively; thus, the novice surgeon will not preoperative training or exposure that can be vital procedures. In addition, there is a lack of reliable models to give surgeons hands-on performing such Methods A technique using an industrial rapid prototyping process by three-dimensional (3D) printing was developed, from...
Persistent Postural-Perceptual Dizziness (PPPD) is a chronic functional disorder which interferes with the way individuals experience their personal, social and work life.To study impact of disease duration in PPPD on quality life (QOL), dizziness handicap mental health patients.A prospective comparing EQ-5D for QOL, Handicap Inventory (DHI) DASS-21 between 27 patients those who have recovered from an acute vestibular event. Similar parameters symptoms less than one year more were...
To assess the antibacterial and antifungal properties of human cerumen by studying its effect on growth Staphylococcus aureus, Esherichia coli, Pseudomonas aeruginosa Candida albicans.Cerumen samples were collected from 75 normal, healthy subjects aged seven to 80 years, without ear pathology, who attended ear, nose throat out-patient clinic University Malaya Medical Center May 2006 October 2006. Of these samples, 31 had no when cultured nutrient agar. Inhibition studies performed for aureus...
Matrix metalloproteinase 13 ( MMP13 ) plays a central role in the MMP activation cascade that enables degradation of extracellular matrix and basement membranes, it is identified as potential driver oral carcinogenesis. Therefore, this study aims to determine copy number, mRNA, protein expression squamous cell carcinoma (OSCC) associate these expressions with clinicopathological parameters. Copy analysis were determined using real-time quantitative PCR immunohistochemistry methods OSCC...
A recognized cause of incomplete or cancelled MRI examinations is anxiety and claustrophobic symptoms in patients undergoing MR scanning. This appears to be a problem many centres Western Europe North America, where it said costly terms loss valuable scan time, has led researchers suggesting several anxiety-reducing approaches for MRI. To determine the incidence failed examination among our if there are any associations with patient's sex, age education level, we studied claustrophobia that...
Abstract Head and neck squamous cell carcinoma (HNSCC) is generalized term that encompasses a diverse group of cancers includes tumours the oral cavity (OSCC), oropharynx (OPSCC) nasopharynx (NPC). Genetic alterations are common to all HNSCC types likely be important for carcinogenesis. In this study, we have investigated role homeodomain-only homeobox gene, HOPX, in pathogenesis HNSCC. We show HOPX mRNA levels reduced OSCC NPC lines tissues there general reduction protein expression these...
Introduction: Persistent postural-perceptual dizziness (PPPD) is a chronic functional vestibular disorder where there persistent or unsteadiness occurring on most days for more than 3 months duration. Treatment recommendations PPPD include rehabilitation therapy (VRT) with without medications and/or cognitive behavioral therapy. Objectives: This paper pilot study designed to compare the effects of Bal Ex as home-based VRT quality life (EQ-5D), handicap (DHI) and mental health (DASS-21)...
Despite the advances in diagnosis and treatment of oral squamous cell carcinoma (OSCC), mortality morbidity rates have not improved over past decade. A major drawback OSCC is lack knowledge relating to how genetic instability cancer genomes affects carcinogenesis. Hence, key aim this study was identify copy number alterations (CNAs) that may be associated using high-resolution array comparative genomic hybridization (aCGH). To our first use ultra-high density aCGH microarrays profile a large...