A5001078382- Ophthalmology and Eye Disorders
- Head and Neck Surgical Oncology
- Nasolacrimal Duct Obstruction Treatments
- Pituitary Gland Disorders and Treatments
- Meningioma and schwannoma management
- Facial Rejuvenation and Surgery Techniques
- Ocular Oncology and Treatments
- Cerebral Venous Sinus Thrombosis
- Facial Trauma and Fracture Management
- Nonmelanoma Skin Cancer Studies
- Sinusitis and nasal conditions
- Cancer and Skin Lesions
- Glaucoma and retinal disorders
- Ocular Surface and Contact Lens
- Dermatologic Treatments and Research
- IgG4-Related and Inflammatory Diseases
- Salivary Gland Tumors Diagnosis and Treatment
- Ocular Disorders and Treatments
- Reconstructive Facial Surgery Techniques
- Traumatic Ocular and Foreign Body Injuries
- Bone Tumor Diagnosis and Treatments
- Hair Growth and Disorders
- Ocular Diseases and Behçet’s Syndrome
- Cutaneous Melanoma Detection and Management
- Corneal Surgery and Treatments
Massachusetts Eye and Ear Infirmary
2016-2025
Harvard University
2016-2025
Boston Children's Hospital
2023-2024
Olympus (Germany)
2023
Medtronic (United States)
2023
Stryker (United States)
2023
Massachusetts General Hospital
2013-2021
Ophthalmology Associates (United States)
2020
Scripps Clinic
2015
Boston University
2006-2011
Endoscopic orbital surgery represents the next frontier in endonasal surgery. The current literature is largely composed of small, heterogeneous, case series with little consensus regarding optimal techniques. purpose this study was to combine experience multiple international centers create a composite global on endoscopic management single type tumor, cavernous hemangioma (OCH).This retrospective techniques for OCH resection from 6 3 continents. Only primary data strictly OCHs were...
We studied the relation between prostaglandin analogue use and ocular adnexal features. used a prospective, cross-sectional study involving 157 current, 15 past, 171 never users of analogues. Patients 50 years age or older without conditions affecting anatomy underwent glaucoma medication history, external digital photography systematic exam. Two masked readers assessed photos for upper lid dermatochalasis lower steatoblepharon using validated grading scheme. Another clinical examiner also...
Invasive fungal infections of the head and neck are rare life-threatening where prompt diagnosis intervention is critical for survival. The aim this study to determine clinical characteristics outcomes invasive disease sinus orbit, compare mucormycosis Aspergillus infection.A retrospective review was conducted from a single tertiary care eye ear hospital over 20 years (1994-2014). Twenty-four patients with confirmed pathological and/or orbit were identified their medical records reviewed....
Background Surgical management of intraconal pathology represents the next frontier in endoscopic endonasal surgery. Despite this, medial space remains a relatively unexplored region, secondary to its variable and technically demanding anatomy. The purpose this study is define neurovascular structures region introduce compartmentalized approach enhance surgical planning. Methods This was an institutional review board (IRB)‐exempt anatomic 10 cadaveric orbits. After dissection space, pattern...
Orbital cavernous hemangiomas (OCH) are the most common adult orbital tumor and represent an ideal index lesion for endonasal surgery. In order to standardize outcomes reporting, anatomic-based staging system was developed.An international, multidisciplinary panel of 23 experts in surgery formed. A modified Delphi method used develop hemangioma exclusively resection (CHEER) with a total 2 rounds being completed.Tumors medial plane along long axis optic nerve may be considered amenable...
This report demonstrates a unique case of conjunctival melanoma harboring BRAF V600E mutation responsive to systemic therapy with and MEK inhibitors. While would not be appropriate in patients local disease alone, it may act therapeutically cases higher stage ocular surface eyelid melanoma.
Purpose: To review the treatment response of advanced conjunctival squamous cell carcinoma (SCC) to systemic immune checkpoint inhibitor (ICI) therapy at a single institution. Methods: A retrospective patients treated institution from 2015 2024 was conducted identify those with SCC who had been ICI therapy. Advanced disease included orbital invasion tumors, unresectable disease, or metastatic disease. Computed tomography imaging and tumor mutational burden data were evaluated for all...
Ophthalmic immune-related adverse events (Eye-irAEs) from immune checkpoint inhibitors can cause visual morbidity. The absence of standardized definitions for Eye-irAEs not only impedes the development evidence-based treatments but also progress in translational research. objective this study was to develop consensus guidance an approach Eye-irAEs. Four ophthalmic physicians (uveitis specialists and neuro-ophthalmologists) drafted Eye-irAE definitions, which were reviewed by...
Immunoglobin G4 (IgG4)-related disease is a systemic condition characterized by lymphoplasmacytic infiltrates that can involve the orbit. The purpose of this study was to identify various patterns orbital IgG4-related on imaging.Retrospective review radiologic examinations including CT, MRI, and positron emission tomography performed in patients with proven cases disease.A total 9 were identified, 4 18-fluorodeoxyglucose tomography. Patterns involvement included lacrimal gland enlargement,...
The aim of this study was to describe a transnasal endoscopic bimanual technique for the removal an intraconal orbital apex cavernous hemangioma. Report surgical technique. A 39-year-old woman with unilateral visual loss and proptosis found have mass consistent radiographically Because its posteromedial location within orbit, 4-handed used pedicled nasoseptal flap reconstruction. tumor excised, patient had no complications. approach hemangioma excision is viable these difficult access...
Abstract Background Postoperative radioactive iodine (RAI) administration is widely utilized in patients with differentiated thyroid cancer. While beneficial select patients, it critical to recognize the potential negative sequelae of this treatment. The prevention, diagnosis, and management salivary lacrimal complications RAI exposure are addressed consensus statement. Methods A multidisciplinary panel experts was convened under auspices American Head Neck Society Endocrine Surgery Salivary...
Giant cell arteritis (GCA) is an age-related vasculitis. Prior studies have identified association between GCA and hematologic malignancies (HMs). How the presence of somatic mutations that drive development HMs, or clonal hematopoiesis (CH), may influence clinical outcomes in not well understood.
The authors report their experience with orbital exenteration surgery at one academic institution over a 10-year period and review the literature. This retrospective cohort study monitored outcomes of all patients who underwent Massachusetts Eye Ear Infirmary between January 2003 2013. Patients no follow-up data or survival were excluded from study. main outcome measures surgical complications, disease status margins, need for adjuvant treatment, local recurrence, metastases survival. 23...
In response to the coronavirus (COVID-19) pandemic, teprotumumab production was temporarily halted with resources diverted toward vaccine production. Many patients who initiated treatment for thyroid eye disease were forced deviate from standard protocol. This study investigates of when receive fewer than 8-dose regimen. observational cross-sectional cohort included 15 institutions active or minimal no clinical activity treated infusion Patients if they had completed at least 1 and not yet...
Purpose: This study analyzed the degree and timing of proptosis regression after teprotumumab therapy. Methods: A retrospective all patients who completed 8 infusions at 1 institution from January 1, 2020 to December 31, 2022. Change in was assessed millimeters percentages compared with immediate post-treatment pretreatment proptosis. Results: Of 119 data (mean follow-up 10.56 months, range: 3.05–25.08), 208 (87.39%) eyes 110 had initial improvement. 78 multiple visits, 102 (65.38%) 59...