A5042645182- Facial Rejuvenation and Surgery Techniques
- Ophthalmology and Eye Disorders
- Traumatic Ocular and Foreign Body Injuries
- Cerebral Venous Sinus Thrombosis
- Reconstructive Facial Surgery Techniques
- Facial Trauma and Fracture Management
- IgG4-Related and Inflammatory Diseases
- Dermatologic Treatments and Research
- Digital Imaging in Medicine
- Intraocular Surgery and Lenses
- Ocular Disorders and Treatments
- Vascular Malformations and Hemangiomas
- Botulinum Toxin and Related Neurological Disorders
- Ocular Diseases and Behçet’s Syndrome
- Facial Nerve Paralysis Treatment and Research
- Glaucoma and retinal disorders
- Sympathectomy and Hyperhidrosis Treatments
- Nasolacrimal Duct Obstruction Treatments
- Craniofacial Disorders and Treatments
- Ocular Oncology and Treatments
- Salivary Gland Tumors Diagnosis and Treatment
- Pituitary Gland Disorders and Treatments
- Sinusitis and nasal conditions
- Cancer and Skin Lesions
- Head and Neck Surgical Oncology
University of Minnesota System
2021-2025
University of Minnesota
2015-2024
University of Minnesota Medical Center
2019
Rice University
2010-2017
Minnesota Lions Eye Bank
2017
Mayo Clinic in Arizona
2016
Mayo Clinic
2006-2013
A noninvasive and cost-effective means to detect preclinical Alzheimer's disease (AD) monitor progression would be invaluable. The retina is a developmental extension of the brain has been viewed as window evaluate AD-related pathology. Cross-sectional studies have shown structural changes in AD patients that include thinning retinal nerve-fiber layer vasculature. However, such do not manifest early stages nor are they specific biomarkers for AD. Described herein utilization our...
A 5-year-old female presented to the ophthalmology clinic with one month of left upper eyelid ptosis and three months intermittent wheezing coughing. MRI brain orbits revealed infiltrative enhancement involving both orbits, including retro-maxillary space, maxillary sinus walls, greater wing sphenoid, possibly cavernous sinus. She experienced acute respiratory decompensation in setting pansinusitis tree-in-bud nodular pulmonary opacifications. Laboratory workup anemia, thrombocytosis,...
In response to the coronavirus (COVID-19) pandemic, teprotumumab production was temporarily halted with resources diverted toward vaccine production. Many patients who initiated treatment for thyroid eye disease were forced deviate from standard protocol. This study investigates of when receive fewer than 8-dose regimen. observational cross-sectional cohort included 15 institutions active or minimal no clinical activity treated infusion Patients if they had completed at least 1 and not yet...
The management issues associated with pediatric ptosis begin determining the etiology of ptosis, and considering how eyelid position affects child's visual psychosocial development. These ultimately determine if when surgical should be undertaken. Surgical challenges include lack intraoperative feedback regarding dynamic height contour under general anesthesia. When elevators do not function or there is little drive to lift involved eyelid, obtaining good outcomes can extremely challenging....
Purpose: To determine effect of upper eyelid surgery on headache symptoms. Methods: Consecutive adults undergoing for obscuration superior visual field, who also reported symptoms greater than 1 year completed a pre- and postoperative Headache Impact Test-6 quality life questionnaire (study group). A cohort patients other oculoplastic procedures with headaches the postoperatively (control The study was conducted over 2-year period. Neither nor investigators were masked. Results: Twenty-eight...
Browpexy surgery is a minimally invasive surgical adjunct to upper blepharoplasty. The traditional internal (IB) approach well documented, while the newer external (EB) variant has only recently been described. To date, there little quantitative data evaluate efficacy of either procedure, and no compare results between two. We determine of, between, browpexy in lifting central lateral brow. A 3.5-year retrospective review patients undergoing assess amount lift brow was performed. Patients...
To measure growth-related changes in orbital volume from childhood to the late teenage years using cone-beam computed tomography (CBCT) scans.This retrospective cohort study involved 65 (24 male, 41 female) healthy Caucasian children (ages 6-18 years) with existing serial craniofacial CBCT scans. scans were available for 292 orbits. Each orbit was transformed into a closed space well-defined boundaries, and measured manual segmentation. A novel statistical analysis applied extract maximum...
To report the long-term outcomes of childhood ptosis surgery in a population-based setting over 46-year period.In this cohort study, medical records all patients who were residents Olmsted County, Minnesota, diagnosed as having blepharoptosis and undergone surgical management prior to 19 years age (between January 1, 1965, December 31, 2010), retrospectively reviewed. Age at time surgery, type duration follow-up, number nature revisions, degree amblyopia, postoperative lagophthalmos dry eye...
To identify risk factors for the development of new-onset, postoperative diplopia following orbital decompression surgery based on patient demographics, clinical exam characteristics, radiographic parameters, and surgical techniques.We conducted a multi-center retrospective chart review patients who underwent thyroid eye disease (TED). Patient including age, gender, smoking history, preoperative exophthalmometry, activity score (CAS), use peribulbar and/or systemic steroids, type were...
An 87-year-old woman presented 11 months after routine phacoemulsification cataract extraction and posterior chamber intraocular lens implantation in her left eye complaining of the abrupt onset redness decreased vision that eye. Examination revealed a mild anterior reaction significant corneal edema. The was minimally responsive to topical steroid therapy, initial serial slitlamp examinations with gonioscopy were unrevealing. After multiple head-positioning maneuvers performed, retained...
A 66-year-old female presented for evaluation of progressively worsening edema and palpable masses in both lower eyelids. While she denied prior filler to the eyelid or tear trough, histopathology revealed degenerating striated muscle surrounding pools hyaluronic acid. cases gradually enlarging associated with facial placement have been reported, there is no literature identifying degeneration adjacent acid filler.
The objective of this study was to observe the effect medical cannabis in benign essential blepharospasm (BEB) as an adjunct botulinum toxin. A retrospective chart review performed on patients certified for use BEB from September 2015 May 2016. Patient demographics and responses, history, severity indices were collected. Ten use. Five met inclusion criteria, which any patient with a diagnosis receiving standard toxin treatment who had started by registered distributor within state,...
Purpose: To describe the demographic and clinical characteristics of patients with thyroid eye disease (TED) who present predominate superior rectus/levator complex involvement.Methods: A multi-institutional retrospective review was performed to identify TED presented isolated or involvement. Baseline subsequent visits were reviewed characterize course.Results: Nineteen identified. All had imaging demonstrating an enlarged levator/superior rectus complex. At presentation, mean activity score...
We investigated the correlation between age and total RNA levels in long-lived control lines of Drosophila melanogaster. Total was extracted at 10 ages from 1-63 days posteclosion 3 inbred lines, with replication. Three different methods quantitation gave highly correlated estimates. declined substantially age, exhibiting a dramatic drop first few adult life. find no evidence for causal relationship longevity levels, since exhibited similar patterns age-related decline. These observations...
Necrobiotic xanthogranuloma (NXG) is a rare non-Langerhans histiocytosis with cutaneous manifestations, most commonly of the periorbital skin, and often associated hematologic disorders such as monoclonal gammopathy. Treatment NXG notoriously difficult, fraught recurrence progression.The authors describe case involvement in patient complex autoimmune medical history. The biopsy this lesion prompted subsequent evaluation for an underlying disorder, which led to diagnosis multiple myeloma. Her...
Introduction Thyroid eye disease (TED) is an immune-mediated disorder associated with a heterogenous array of manifestations that may unfavorably impact vision and quality life. As understanding this entity’s complex pathogenesis has evolved, so have therapies novel molecular targets offering promise for improved patient outcomes. Results Emerging immunologic the management thyroid diverse mechanisms actions routes administration. Different conventional biological immunosuppressive agents...
A 10-year-old male was referred for evaluation of a right orbital mass present 3 weeks with associated tenderness to palpation. Magnetic resonance imaging (MRI) and computed tomography (CT) revealed solid centered in the frontal bone extension into orbit. Surgical excision histologic analysis lesion consistent diagnosis Giant Cell Tumor (GCT) bone. The patient tolerated procedure without complication is doing well upon follow-up.
A 64-year-old woman with relapsed acute myelogenous leukemia (AML) undergoing salvage chemotherapy developed rapid onset of right-sided ophthalmoplegia, proptosis, optic neuropathy, and vision loss from 20/30 to hand motions over a 3-hour period on day 4 her treatment. CT scan orbits revealed superolateral orbital mass periocular edema. She underwent immediate canthotomy cantholysis, lateral orbitotomy debulking the later same day. The histopathology was consistent aggregates myeloid blasts....
Purpose: To demonstrate the utility of an ultrasonic aspirator (Sonopet, Stryker Corporation; Kalamazoo, MI) for debulking firm, soft tissue masses orbit. Methods: Case series. The was used to debulk in 3 cases. initial patient had a large orbitofacial mass extending inferior and lateral orbital apex secondary IgG4 disease. second lacrimal sac adenocarcinoma medial apex. third granulomatosis with polyangiitis. Results: facilitated infiltrative firm device’s ability emulsify, irrigate,...
Lichen sclerosus is a chronic, debilitating, and recurring disease that most commonly seen affecting the anogenital region. Extragenital locations of lichen has been well documented, frequently in shoulders, neck, trunk, breasts, arms, however, infrequently face. Specifically, extragenital reported several cases to be involving infraorbital region, but our knowledge it never found adnexa eye. To understanding, this first documented report patient with an eyelid.
Purpose: To analyze the clinical significance of periorbital features associated with facial asymmetry that is common in deformational posterior plagiocephaly (DPP).Patients and methods: We identified 32 patients DPP, photographed their faces tops head, performed a complete eye examination. Four examiners analyzed patient's on photographs.Results: Median age was 6.5 months (range 3–12 months). Pseudoptosis 30 pseudo-brow ptosis 19. marked 17 patients. Five were misdiagnosed congenital...
Traumatic penetrating injuries to the orbit from pencils, while uncommon, have a plethora of presentations, both acute and delayed. With most incidents occurring in pediatric population where obtaining detailed history is difficult, ability effectively evaluate diagnose these cumbersome, yet important. The authors report patient who presented with optic neuropathy, blepharoptosis, strabismus 10 months after an orbital injury pencil graphite.