- Retinal and Optic Conditions
- Cerebral Venous Sinus Thrombosis
- Ocular Diseases and Behçet’s Syndrome
- Vasculitis and related conditions
- Intraoperative Neuromonitoring and Anesthetic Effects
- Meningioma and schwannoma management
- Traumatic Ocular and Foreign Body Injuries
- Neurofibromatosis and Schwannoma Cases
- Cerebrovascular and Carotid Artery Diseases
- Acute Ischemic Stroke Management
- Intracranial Aneurysms: Treatment and Complications
- Glaucoma and retinal disorders
- Ocular Oncology and Treatments
- Vascular Malformations Diagnosis and Treatment
- Ophthalmology and Eye Disorders
- Trigeminal Neuralgia and Treatments
- Cerebrospinal fluid and hydrocephalus
- Migraine and Headache Studies
- Neurological Complications and Syndromes
- Genetic Neurodegenerative Diseases
- Traumatic Brain Injury and Neurovascular Disturbances
- Retinal Development and Disorders
- Drug-Induced Ocular Toxicity
- Epilepsy research and treatment
- Sympathectomy and Hyperhidrosis Treatments
Providence Medford Medical Center
2021-2024
California Pacific Medical Center
2022
Highland Hospital
2022
Rockwood Clinic
2018-2020
Washington University in St. Louis
2015
Carnegie Mellon University
2012-2014
Napa Valley College
2013
Oregon Health & Science University
1999-2012
St. Helena Hospital
2009-2012
Center for the Neural Basis of Cognition
2012
Defects in oxidative metabolism have been implicated Alzheimer's disease (AD). The present study evaluated the level of cytochrome oxidase (C.O.), an indicator neuronal capacity, various brain regions post-mortem AD and control patients. We found a statistically significant reduction C.O. levels all cortical areas examined, including primary secondary visual cortices. In addition, layers dorsal lateral geniculate nucleus sublaminae cortex cases examined suffered their relative activity...
Abstract Cytochrome-oxidase (CO) histochemistry has revealed important functional subdivisions, modules, and processing streams in the macaque visual cortex. The present study is aimed at analyzing development characteristics of CO patterns human cortex by means immunohistochemistry. At 26 weeks gestation, both ventricular subventricular zones had low levels CO, while cortical plate moderate CO. birth, supragranular CO-rich (puffs) were not clearly organized, indicating that puffs neonatal...
Ophthalmic immune-related adverse events (Eye-irAEs) from immune checkpoint inhibitors can cause visual morbidity. The absence of standardized definitions for Eye-irAEs not only impedes the development evidence-based treatments but also progress in translational research. objective this study was to develop consensus guidance an approach Eye-irAEs. Four ophthalmic physicians (uveitis specialists and neuro-ophthalmologists) drafted Eye-irAE definitions, which were reviewed by...
To evaluate and identify the incidence of visual field defects (VFD) after anterior temporal lobectomy (ATL) versus amygdalohippocampectomy (AH). VFD occur frequently ATL are usually superotemporal quadrantanopias. Little is known about AH this surgical method offers possibility a seizure-free survival without loss.Patients with similar characteristics were examined. All patients had intractable seizures mesial sclerosis, small tumors localized to only uncus, amygdala, or hippocampus, no...
<h3>Objective</h3> To describe the natural history of patients with primary optic nerve sheath meningioma (ONSM) who were cared for without intervention. <h3>Methods</h3> A retrospective review medical records 42 identified in database an academic neuro-ophthalmology unit had been diagnosed a unilateral ONSM. Twenty-five referred after treatment implemented, and 1 was blind at referral. The remaining 16 followed up observation only are focus this study. <h3>Results</h3> study subjects mean...
The authors report seven patients from six neuro-ophthalmology referral centers who developed pseudo-tumor cerebri during treatment with doxycycline. All four female and one of three male were obese. Vision was minimally affected in most patients, but two had substantial visual acuity or field loss at presentation. Discontinuation doxycycline, without additional intracranial pressure-lowering agents, yielded improvement, permanent occurred five patients.
Abstract Deficits or atypicalities in attention have been reported individuals with autism spectrum disorder (ASD), yet no consensus on the nature of these deficits has emerged. We conducted three experiments that paired a peripheral precue covert discrimination task, using protocols for which effects exogenous spatial early vision well established typically developing populations. Experiment 1 assessed changes contrast sensitivity, orientation contrast-defined grating; 2 evaluated reduction...
<h3>Objective:</h3> To test efficacy and safety of atorvastatin in subjects with clinically isolated syndrome (CIS). <h3>Methods:</h3> Subjects CIS were enrolled a phase II, double-blind, placebo-controlled, 14-center randomized trial testing 80 mg on clinical brain MRI activity. Brain MRIs performed quarterly. The primary endpoint (PEP) was development ≥3 new T2 lesions, or one relapse within 12 months. meeting the PEP offered additional weekly interferon β-1a (IFNβ-1a). <h3>Results:</h3>...
The ophthalmic findings of Susac syndrome (SS) consist visual field defects related to branch retinal artery occlusion (BRAO), and fluorescein angiography (FA) reveals a unique staining pattern. To date, arterial collateral development has been described only in single patient. Given that the immunopathological process SS induces ischemia, it is conceivable abnormal blood vessel may occur affected individuals.This retrospective observational study. medical records including fundus...
Background: Susac syndrome is a vasculopathy, resulting in the classic triad of branch retinal artery occlusion (BRAO), inner ear ischemia, and brain ischemia. In this retrospective chart review, we characterize fluorescein angiography (FA) findings other ancillary studies syndrome, including appearance persistent disease activity occurrence new subclinical on FA. Methods: This multicenter, case series was institutional review board–approved included patients with complete evaluated FA,...