A5023290219- Retinal and Optic Conditions
- Ocular Diseases and Behçet’s Syndrome
- Vasculitis and related conditions
- Cerebral Venous Sinus Thrombosis
- Glaucoma and retinal disorders
- Neuroscience and Music Perception
- Multisensory perception and integration
- Ophthalmology and Eye Disorders
- Sports and Physical Education Research
- Neural dynamics and brain function
- Drug-Induced Ocular Toxicity
- Peripheral Neuropathies and Disorders
- Neurosurgical Procedures and Complications
- Children's Physical and Motor Development
- Genetic Neurodegenerative Diseases
- Sports Performance and Training
- Otitis Media and Relapsing Polychondritis
- Long-Term Effects of COVID-19
- Traumatic Brain Injury and Neurovascular Disturbances
- Neurological and metabolic disorders
- Multiple Sclerosis Research Studies
- Neurobiology of Language and Bilingualism
- Cerebrospinal fluid and hydrocephalus
- Hearing Loss and Rehabilitation
- Sarcoidosis and Beryllium Toxicity Research
Beth Israel Deaconess Medical Center
2016-2024
Massachusetts General Hospital
2017-2024
Massachusetts Eye and Ear Infirmary
2017-2024
Harvard University
2016-2024
Boston Children's Hospital
2023
Brigham and Women's Hospital
2018-2022
University of Pennsylvania
2022
Hadassah Medical Center
2020-2022
Hospital of the University of Pennsylvania
2022
Université de Montréal
2002-2010
Morphological asymmetries favouring the left hemisphere in planum temporale (PT) and Heschl's gyrus (HG) have both been presumed to relate typical left-hemisphere dominance for language functions. However, a direct link between structure function has not clearly established. The present study investigates this issue by measuring volume of PT HG on MRI scans epilepsy patients classified into three groups: speech group (LSG; n = 20), right (RSG; 11) bilateral (BSG; 13), as assessed...
This positron emission tomography study examined the hemodynamic response of human brain to auditory object feature processing. A continuum variation was created by combining different numbers stimuli drawn from a diverse sample 45 environmental sounds. In each 60 sec scan condition, subjects heard either distinct individual sound on trial or simultaneous combinations sounds that varied systematically in their similarity distinctiveness across conditions. As more are combined they become...
Abstract Two fMRI experiments explored the neural substrates of a musical imagery task that required manipulation imagined sounds: temporal reversal melody. Musicians were presented with first few notes familiar tune (Experiment 1) or its title 2), followed by string was either an exact inexact reversal. The to judge whether second correct not mentally reversing all notes, thus requiring both maintenance and represented string. Both showed considerable activation superior parietal lobe...
Abstract Introduction/Aims Myasthenia gravis (MG) is a rare, life‐threatening immune‐related adverse effect (irAE) of immune checkpoint inhibitor (ICI) treatment. C5‐complement inhibitors are effective treatments for acetylcholine receptor antibody (AChR ab) positive generalized MG. We describe the use eculizumab/ravulizumab in two patients with MG receiving concomitant pembrolizumab. Methods This was retrospective review medical records. Results Patient 1: An 80‐year‐old male recurrent,...
Our major purpose is to develop a more holistic model of the development skilled action that can guide our research and practical efforts help physically awkward persons enjoy benefits physical activity. Based on recent in areas cognitive science development, we suggest motor be viewed as acquisition three types knowledge about action: procedural, declarative, affective. A brief discussion how each type might presented. The final section examines complementary role consciousness implications...
Background: Susac syndrome is a vasculopathy, resulting in the classic triad of branch retinal artery occlusion (BRAO), inner ear ischemia, and brain ischemia. In this retrospective chart review, we characterize fluorescein angiography (FA) findings other ancillary studies syndrome, including appearance persistent disease activity occurrence new subclinical on FA. Methods: This multicenter, case series was institutional review board–approved included patients with complete evaluated FA,...
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Transient monocular vision loss (TMVL) is an alarming symptom owing to potentially serious etiologies such as thromboembolism or giant cell arteritis. Our objective describe the phenomenon of TMVL present on awakening, which may represent a distinct and benign entity.We performed retrospective observational case series 29 patients who experienced awakening. Patients described dimming blackout were included, those with blurred vision, concurrent eye pain, binocular excluded. Descriptive...
There are no data in the literature regarding safety of re-treatment with ethambutol for recurrent mycobacterial infection after prior ethambutol-induced optic neuropathy. We describe a patient who developed neuropathy attributed to ethambutol, recovered fully drug withdrawal, and tolerated 14-month long 10 years later without developing
Mukharesh, Loulwah MD; Bouffard, Marc A. Fortin, Elizabeth Brann, David H.; Datta, Sandeep Robert MD, PhD; Prasad, Sashank Chwalisz, Bart K. MDEditor(s): Avery, DO; Golnik, Karl C. Froment, Caroline Wang, An-Guor MD Author Information
Data generation, driven by rapid advances in genomic technologies, is fast outpacing our analysis capabilities. Faced with this flood of data, more hardware and software resources are added to accommodate data sets whose structure has not specifically been designed for analysis. This leads unnecessarily lengthy processing times excessive handling storage costs. Current efforts address have centered on developing new indexing schemas algorithms, whereas the root problem lies format itself. We...
Purpose of review Optic neuritis can result from several distinct causes, including multiple sclerosis (MS), neuromyelitis optica spectrum disorder (NMOSD), and myelin oligodendrocyte glycoprotein antibody disease (MOGAD), when not idiopathic. This discusses evidence-based treatment approaches contingent upon each specific cause optic neuritis. Recent findings Current evidence highlights the need for prompt plasmapheresis as adjunct to intravenous methylprednisolone (IVMP) in patients with...
Background: Despite appropriate use of corticosteroids, an important minority patients with giant cell arteritis (GCA) develop progressive vision loss during the initial stages disease or corticosteroid tapering. Tocilizumab is only clearly effective adjunctive treatment to corticosteroids in management GCA, but questions regarding its efficacy specifically neuro-ophthalmic population and role mitigating have not been broached until recently. Evidence Acquisition: The authors queried Pubmed...