A5087536545- Hepatocellular Carcinoma Treatment and Prognosis
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Liver Disease Diagnosis and Treatment
- Liver Disease and Transplantation
- Renal cell carcinoma treatment
- MRI in cancer diagnosis
- Lung Cancer Treatments and Mutations
- Radiopharmaceutical Chemistry and Applications
- Organ Transplantation Techniques and Outcomes
- Advanced Radiotherapy Techniques
- Pancreatic and Hepatic Oncology Research
- Venous Thromboembolism Diagnosis and Management
- Radiomics and Machine Learning in Medical Imaging
- Gallbladder and Bile Duct Disorders
- Medical Imaging and Pathology Studies
- Hepatitis B Virus Studies
- Cancer, Hypoxia, and Metabolism
- Lung Cancer Research Studies
- Colorectal Cancer Treatments and Studies
- Central Venous Catheters and Hemodialysis
- Neuroendocrine Tumor Research Advances
- Prostate Cancer Diagnosis and Treatment
- Neuroblastoma Research and Treatments
- Advanced MRI Techniques and Applications
- Lung Cancer Diagnosis and Treatment
Northwestern University
2016-2025
Northwestern Memorial Hospital
2016-2025
Northwestern University
2005-2024
University of California, San Francisco
2024
The University of Texas Southwestern Medical Center
2024
Midstate Medical Center
2024
Northwestern Medicine
2008-2024
Society of Interventional Radiology
2008-2024
National Institutes of Health
2024
Yale University
2024
Image-guided tumor ablation has become a well-established hallmark of local cancer therapy. The breadth options available in this growing field increases the need for standardization terminology and reporting criteria to facilitate effective communication ideas appropriate comparison among treatments that use different technologies, such as chemical (eg, ethanol or acetic acid) ablation, thermal therapies radiofrequency, laser, microwave, focused ultrasound, cryoablation) newer ablative...
Chemoembolization is one of several standards care treatment for hepatocellular carcinoma (HCC). Radioembolization with Yttrium-90 microspheres a novel, transarterial approach to radiation therapy. We performed comparative effectiveness analysis these therapies in patients HCC.We collected data from 463 who were treated locoregional (chemoembolization or radioembolization) over 9-year period. excluded not appropriate comparison and analyzed 245 (122 received chemoembolization 123...
This study was undertaken to present data from a phase 2 in which patients with unresectable hepatocellular carcinoma (HCC) and without portal vein thrombosis underwent radioembolization Yttrium (90Y) microspheres. Patients treated were stratified by Okuda, Child-Pugh, baseline bilirubin, tumor burden, Eastern Cooperative Oncology Group (ECOG), presence of cirrhosis (PVT) (none, branch, main). Clinical biochemical obtained at 4-week intervals following treatment for up 6 months. Tumor...
Conventional transarterial chemoembolization (cTACE) is used to treat patients with hepatocellular carcinoma (HCC). Radioembolization a minimally invasive procedure that involves implantation of radioactive micron-sized particles loaded yttrium-90 (Y90) inside the blood vessels supply tumor. We performed randomized, phase 2 study compare effects cTACE and Y90 radioembolization in HCC.
Purpose: The use of 90Y-microspheres to treat unresectable liver metastases originating from a variety neuroendocrine tumors was reviewed. Materials and Methods: This is retrospective review 10 institutions patients given 90Y-microsphere therapy for hepatic metastases. Physical, radiographic, biochemical, clinical factors associated with treatment response were examined. All followed laboratory imaging studies at regular intervals until death, or censured whether other after brachytherapy....
Locoregional therapies, including yttrium-90 radioembolization, play an important role in the treatment of unresectable HCC. The aim LEGACY (Local radioEmbolization using Glass Microspheres for Assessment Tumor Control with Y-90) study was to evaluate objective response rate (ORR) and duration (DoR) patients solitary HCC treated glass microspheres.LEGACY is a multicenter, single-arm, retrospective conducted at three sites that included all eligible, consecutive radioembolization between 2014...
To present the clinical data of 35 patients with T3 unresectable hepatocellular carcinoma (HCC) that were treated (90)Y specific intent downstaging to resection, radiofrequency ablation (RFA) candidate, United Network for Organ Sharing (UNOS) stage T2 or liver transplantation.One hundred fifty HCC microspheres. Of these, UNOS at time treatment. Patients followed toxicities, alterations in model end-stage-liver disease (MELD) score, tumor response, RFA, transplantation, and survival.Nineteen...
Neuroendocrine tumors affect cells throughout the nervous and endocrine systems that produce secrete regulatory hormones. Common sites of origin include pancreas; parathyroid, adrenal, pituitary glands; calcitonin-producing thyroid (causing medullary carcinoma); argentaffin gut carcinoid tumors). are rare can be broadly subdivided into those with without a clinical syndrome. Most neuroendocrine malignant metastasize commonly to lymph nodes liver or less bone, lung, brain, other organs....
Resection and radiofrequency ablation (RFA) are treatment options for hepatocellular carcinoma (HCC) <3 cm; there is interest in expanding the role of to 3-5 cm. RFA considered high-risk when lesion close proximity critical structures. Combining microcatheter technology localized emission properties Y90, highly selective radioembolization a possible alternative such cases. We assessed efficacy (response, radiology-pathology correlation, survival) radiation segmentectomy solitary HCC not...