A5076959478- Cleft Lip and Palate Research
- Craniofacial Disorders and Treatments
- Cardiac, Anesthesia and Surgical Outcomes
- dental development and anomalies
- Facial Trauma and Fracture Management
- Reconstructive Surgery and Microvascular Techniques
- Bone Tissue Engineering Materials
- Breast Implant and Reconstruction
- Dental Radiography and Imaging
- Nail Diseases and Treatments
- Periodontal Regeneration and Treatments
- Cutaneous lymphoproliferative disorders research
- Spinal Fractures and Fixation Techniques
- Intensive Care Unit Cognitive Disorders
- Surgical Simulation and Training
- Eosinophilic Disorders and Syndromes
- Healthcare Systems and Public Health
- Nerve injury and regeneration
- Spinal Cord Injury Research
- Connective tissue disorders research
- Diversity and Career in Medicine
- Nursing Roles and Practices
- Innovations in Medical Education
- Pain Management and Treatment
- Cardiac Arrest and Resuscitation
Addenbrooke's Hospital
2023
Outcomes Research Consortium
2023
Cleveland Clinic
2022-2023
University of Cambridge
2014-2023
Papworth Hospital NHS Foundation Trust
2023
Cambridge University Hospitals NHS Foundation Trust
2023
Anglia Ruskin University
2023
Center For Reconstructive Urethral Surgery
2023
Cambridge School
2023
University of Pittsburgh Medical Center
2019-2022
A polycaprolactone conduit containing growth factor–encapsulated microspheres repairs 5-cm median nerve defects in rhesus macaques.
In just over 100 years, surgical education in the United States has evolved from a disorganized practice to refined system esteemed worldwide as one of premier models for training physicians and surgeons. But changing environment health care, new challenges have arisen that could warrant reform. To design our future, we must understand past. The present work is not intended be comprehensive account history American surgery. Instead, it tells abridged country: evolution apprenticeships...
Importance Mobilization after surgery is a key component of Enhanced Recovery Surgery (ERAS) pathways. Objective To evaluate the association between mobilization and collapsed composite postoperative complications in patients recovering from major elective as well hospital length stay, cumulative pain scores, 30-day readmission rates. Design, Setting, Participants This retrospective observational study conducted at single quaternary US referral center included who had February 2017 October...
Objectives: The use of cone-beam computed tomography (CBCT) is well-established in clinical practice. This study seeks to categorize and quantify the incidental finding (IF) rate on CBCT patients with cleft lip palate (CLP) prior orthodontic or surgical treatment. Methods: systematic retrospective review head neck CBCTs nonsyndromic CLP taken between 2012 2019 at a single tertiary referral center. All assessments were performed independently by 4 observers (a radiologist 3 orthodontists,...
Most cardiac surgery patients experience postoperative anemia. Delirium and Atrial Fibrillation (AF) are common independent predictors of morbidity mortality. Few reports examine their association with This study aims to quantify the between anemia these outcomes in undergoing surgery.
Background: The submucous cleft palate can be overt or occult and may require surgical repair. double-opposing Z-plasty (Furlow repair) is the authors’ center’s preferred approach. This study evaluated complication rates, differences in outcome between types, patient factors associated with failure. Methods: retrospective reviewed documentation on all patients who underwent Furlow for at a single center 2004 2018. Speech pathology was quantified using Pittsburgh Weighted Score. Results: A...
Bone morphogenetic protein 2 (BMP2) bioprinted on biological matrix induces osseous regeneration in large calvarial defects rabbits, both uncomplicated and scarred. Healing unfavorable scarred from previous infection is decreased due part to the lack of vascularity. This impedes access mesenchymal stem cells, key efficacy BMP2, wound bed. The authors hypothesized that vascular endothelial growth factor (VEGF) would augment achieved with low dose biopatterned BMP2 alone. Thirteen New Zealand...
Pierre Robin Sequence (PRS) can be associated with skeletal dysplasias, presenting craniocervical instability and devastating spinal injury if unrecognized. The authors present the case of an infant PRS a type II collagenopathy who underwent multiple airway-securing procedures requiring manipulation before was identified. This resulted in severe cervical cord compression due to odontoid fracture occipitoatlantoaxial instability. highlights importance early spine imaging cautious infants...
An increasing body of evidence suggests that a postoperative rise in cardiac troponin, even the absence other diagnostic criteria for myocardial infarction, is still associated with range complications including death and all-cause mortality. Myocardial injury after non-cardiac surgery term used to describe these cases. The true incidence unknown likely underestimated. strength correlation also uncertain as are risk factors - though similar those infarction given pathological mechanism. This...
Background: Large calvarial defects represent a major reconstructive challenge, as they do not heal spontaneously. Infection causes inflammation and scarring, further reducing the healing capacity of calvaria. Bone morphogenetic protein-2 (BMP2) has been shown to stimulate osteogenesis but significant side effects in high doses. BMP2 tested combination with antiinflammatory cytokines such interleukin-10. Methods: Sixteen New Zealand White rabbits underwent 15 × 15-mm flap calvarectomies. The...
Maxillo-mandibular fixation (MMF) is common technique used in mandibular fractures to stabilize the fragments and maintain patient normal dental occlusion during healing process. Arch bars with elastics are one of most frequently methods MMF temporary, designed be removed after process completed. There controversy as what impact hardware has on hygiene oral health. No reports long-term retention exist. This report details case arch retained for 14 years. The underwent internal at age 16 a...
Augmentation mammoplasty is the most common aesthetic surgical procedure performed in USA. Prosthetic failure a major reason for reintervention. A number of causes this have been documented, but costal bone abnormalities leading to perforation prosthesis are very unusual. We present case woman who experienced spontaneous deflation both saline implants close succession, and was found sharp bony spicules on sides her chest. Pathology examination reported reactive changes, suggestive...
Introduction and aims Donor site seroma following abdominal flap harvest for breast reconstruction is common in both deep inferior epigastric artery perforator (DIEP) superficial (SIEA) flaps. We tested the hypothesis that there increased donor fluid SIEA dissection compared to DIEP. Materials methods Of60 reconstructions performed by one surgeon 50 patients (2004-2019), complete data were available 31 patients. Eighteen unilateral SIEAs matched with 18 DIEPs. Thirteen bilateral harvests...
Introduction Complex Regional Pain Syndrome (CRPS) is a debilitating neuropathic condition often refractory to conventional treatments. N-methyl-D-aspartate (NMDA) receptor antagonists have well-established role in the development and modulation of chronic pain. Nitrous oxide widely used generally safe anesthetic gas with NMDA antagonist activity. We therefore tested hypothesis that brief periods nitrous exposure reduce pain patients CRPS. Methods Patients diagnosis CRPS were randomized...
INTRODUCTION: The condyle has been described as an important growth center for the mandible. Fractures to could affect occlusal relationships, jaw growth, and orofacial functions. To date, there have few reports assessing long-term after pediatric condylar fractures. METHODS: This is a retrospective study at Children’s Hospital of Pittsburgh (2000–2016). Patients with fractures identified by ICD-9 code >1y follow-up cephalograms were included. We examined demographics, mechanism, management,...
INTRODUCTION: Overt submucous cleft palate (SMCP) is characterized by Calnan’s triad of bifid uvula, hard notch and zona pellucida. Because occult SMCP (OSMCP) lacks this triad, diagnosis challenging treatment (if indicated the presence velopharyngeal insufficiency [VPI]) delayed. This study discusses diagnosis, treatment, long-term outcomes OSMCP. METHODS: A retrospective chart review was performed for all patients presenting to Cleft-Craniofacial Center Children’s Hospital Pittsburgh who...
BACKGROUND: Patients with cleft lip and palate frequently undergo nasoalveolar molding (NAM) or adhesion (LA) to guide the segments together in preparation for definitive repair. This study reports effect of these primary interventions on eventual permanent incisor inclination. METHODS: is a retrospective at tertiary craniofacial center. unilateral bilateral palate, who had undergone LA NAM, follow-up imaging between ages 7–9 were included. further categorized based gingivoperiostioplasty...