- Extracellular vesicles in disease
- Advanced Glycation End Products research
- Respiratory Support and Mechanisms
- Epigenetics and DNA Methylation
- Circular RNAs in diseases
- Medical Imaging and Analysis
- Orthopaedic implants and arthroplasty
- Venomous Animal Envenomation and Studies
- Autophagy in Disease and Therapy
- MicroRNA in disease regulation
- Opioid Use Disorder Treatment
- Spine and Intervertebral Disc Pathology
- Diabetic Foot Ulcer Assessment and Management
- RNA modifications and cancer
- Signaling Pathways in Disease
- Nerve injury and regeneration
- Forensic Toxicology and Drug Analysis
- Eicosanoids and Hypertension Pharmacology
- Pressure Ulcer Prevention and Management
- Ferroptosis and cancer prognosis
Xinjiang Medical University
2024
Wenzhou Medical University
2022
Lung cancer is the most common with high morbidity and mortality worldwide. Our previous studies showed that fucosyltransferase 2 (FUT2) highly expressed in lung adenocarcinoma (LUAD) plays a vital role tumorigenesis of LUAD. However, underlying mechanism not fully understood. Autophagy has recently attracted increasing attention due to its pro-survival progression metastasis. Here, we found FUT2 was up-regulated had an AUC (Area Under Curve) value 0.964 based on TCGA dataset. Knockdown...
Diacetylmorphine abuse is a major social problem that jeopardizes the world, and can cause serious neurological disorders. Apoptosis plays an important role in diseases. A previous study by our group found brain tissue of diacetylmorphine-addicted rats showed severe vacuole-like degeneration increased apoptosis, but exact mechanism has not yet been reported. We used TMT technology to sequence diseased rats, selected neurofilament light chain (NEFL) neuritin (NRN1) as focus research. explore...
Objective: This meta-analysis aimed to assess and compare the clinical effectiveness, safety, biochemical impacts of two spinal surgery techniques: open transforaminal lumbar interbody fusion (open-TLIF) minimally invasive TLIF (MIS-TLIF). Methods: A comprehensive search literature up April 2023 was conducted across several databases, including PUBMED, Cochrane Library, SCOPUS, Web Science, EMBASE, CNKI. The focused on terms "transforaminal fusion" or "TLIF" combined with "minimally...
Diacetylmorphine (DA) is widely implicated in neuronal injury; however, the underlying mechanisms remain unclear. We investigated role of iron metamorphosis DA-induced neurotoxicity using Sprague-Dawley rats and PC12 SH-SY5Y cells. Tandem mass tag proteomics analysis showed that upregulation protein kinase C delta (PKCδ) metabolism-related transferrin receptor (TFRC) significantly enriched metabolism pathway. Subsequent experiments DA exposure upregulated PKCδ cells, which increased nuclear...