Paweł Łęgosz

ORCID: 0000-0001-9799-5750
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About
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Research Areas
  • Orthopaedic implants and arthroplasty
  • Total Knee Arthroplasty Outcomes
  • Heterotopic Ossification and Related Conditions
  • Hip and Femur Fractures
  • Orthopedic Infections and Treatments
  • Cardiac, Anesthesia and Surgical Outcomes
  • Hip disorders and treatments
  • Musculoskeletal pain and rehabilitation
  • Spine and Intervertebral Disc Pathology
  • Nutrition and Health Studies
  • Genetic Syndromes and Imprinting
  • Medical Imaging and Pathology Studies
  • Hemophilia Treatment and Research
  • Cardiac Valve Diseases and Treatments
  • Bone fractures and treatments
  • Neurogenetic and Muscular Disorders Research
  • Bone and Joint Diseases
  • Protease and Inhibitor Mechanisms
  • Periodontal Regeneration and Treatments
  • Tendon Structure and Treatment
  • Mesenchymal stem cell research
  • Frailty in Older Adults
  • Rheumatoid Arthritis Research and Therapies
  • Shoulder Injury and Treatment
  • Child and Adolescent Health

Medical University of Warsaw
2015-2024

University School of Physical Education in Kraków
2022

Clinical Orthopaedics and Related Research
2021

National Institute of Traumatology & Orthopaedic Rehabilitation
2018

University of Warsaw
2018

Abstract Biofilms are microbial communities of surface-attached cells embedded in a self-produced extracellular matrix. They have been found to play role wide variety infections, including catheter-related urinary tract and bloodstream and, therefore remain significant source morbidity mortality among the world's population. Recently, much attention has devoted prevention biofilm formation on implant surfaces. Nanomaterials such as graphene, characterized by antibacterial activity low...

10.5740/jaoacint.17-0164 article EN Journal of AOAC International 2017-06-17

Total knee arthroplasty (TKA) is a frequently performed procedure in orthopaedic surgery. Recently, patient-specific instrumentation was introduced to facilitate correct positioning of implants. The aim this study compare the early clinical results TKA with CT-based and conventional technique. A prospective, randomized controlled trial on 112 patients between January 2011 December 2011. group who met inclusion exclusion criteria were enrolled randomly assigned an experimental or control...

10.1155/2015/165908 article EN cc-by BioMed Research International 2015-01-01

Objectives Total hip arthroplasty (THA) is a well-approved method for the treatment of end-stage osteoarthritis (OA). Due to rising life expectancy, elderly patients burdened with multimorbidity are subjected THA. Some these present significant depletion physiological reserves, which described as frailty syndrome. This study aims assess influence on THA outcomes in OA patients. Material and methods A single-center observational was conducted investigate effect measured by modified index-5...

10.5114/reum.2020.98433 article EN cc-by-nc-sa Reumatologia/Rheumatology 2020-08-31

Abstract Background Mesenchymal stem/stromal cells (MSC) are commonly used in regenerative medicine. Among different tissues, iliac crest bone marrow (BM) represents the most exploited source, but its disadvantages a painful aspiration procedure and low cell number. An alternative, readily available source of MSC for research would be beneficial medicine development. This work aimed to propose new isolation which femoral shaft is taken during total hip arthroplasty (THA). Methods In...

10.1186/s13287-020-01697-5 article EN cc-by Stem Cell Research & Therapy 2020-06-30

Background and Objectives: Developmental dysplasia of the hip (DDH) is one most common musculoskeletal conditions in children. If not treated, it leads to disability, gait abnormalities, limb shortening, chronic pain. Our study aims determine impact multiple risk factors on incidence DDH develop an interactive assessment tool. Materials Methods: We conducted a retrospective cohort Outpatient Clinic for Children Medical University Warsaw Hospital. The Graf classification system was used...

10.3390/medicina58091158 article EN cc-by Medicina 2022-08-25

Carpal tunnel syndrome (CTS) is a condition caused by chronic compression of the median nerve. The diagnosis made mainly on basis clinical image and confirmed with electrodiagnostic testing (electromyography nerve conduction study); however, these methods do not always aid in reaching CTS. Moreover, they are invasive examinations, unpleasant for patient have to be performed qualified physician.An evaluation usefulness dynamic thermography CTS.Forty patients were included study group. CTS was...

10.1515/med-2021-0007 article EN cc-by Open Medicine 2021-01-01

Wstęp: Ocena ryzyka ma szczególne znaczenie u pacjentów poddawanych interwencjom chirurgicznym. Zabiegi ortopedyczne, w szczególności całkowita alloplastyka stawów, są operacjami związanymi z wysokim ryzykiem okołooperacyjnym, jak również jednym najwyższych odsetków powikłań. Cel: Celem niniejszej pracy było określenie częstości występowania klasycznych i nieklasycznych czynników sercowo-naczyniowego całkowitej alloplastyce stawu biodrowego lub kolanowego. Metody: CRASH-JOINT (...

10.5603/kp.a2016.0162 article PL Kardiologia Polska 2016-11-23

The treatment of end-stage hemophilic arthropathy the ankle joint remains a controversial problem, and total replacement (TAR) is considered to be valuable management option. Physiotherapy continues an extremely important part TAR has tremendous impact on outcomes this procedure. Given lack data latter, study details protocol perioperative physiotherapy in patients with inherited bleeding disorders (IBD). outlined paper was devised via consultations within interdisciplinary group, authors'...

10.12659/msm.898075 article EN Medical Science Monitor 2017-01-27

BACKGROUND:The results of total knee arthroplasty (TKA) in patients with inherited bleeding disorders (IBDs) are poorer when compared those the general population, a notably higher risk complications and revision rates. Thus, procedures becoming growing concern this group patients. The aim study was to evaluate TKA IBD. MATERIAL AND METHODS:A retrospective cohort longitudinal assessment hemophilia scheduled for between January 2010 September 2015 performed. clinical status assessed based on...

10.12659/msm.899580 article EN Medical Science Monitor 2017-01-09

Periodontal disease is a chronic causing an inflammatory process that affects various organs and as-sociated with increased risk of many diseases, including bone cardiovascular disease.The aim this study was to establish the prevalence periodontal in continuous patients scheduled for hip or knee replacement surgery.The prospective, epidemiological analysis performed consecutive total joint (hip knee) surgery. Patients enrolled into were screened classical factors had dental evaluation...

10.5603/kp.a2017.0263 article EN Kardiologia Polska 2018-01-03

Total hip arthroplasty (THA) is considered the gold standard in treatment of advanced osteoarthritis hip. The aim this study was to compare incidence heterotopic ossification (HO), quality life and function two groups patients who underwent total (THA), performed using anterior minimally invasive (MIS) anterolateral approaches.Retrospective analysis 597 THA 2009-2013 performed. In all cohort data on medical history were retrieved. HO occurrence recorded for 331 evaluated based Brooker's...

10.5114/aoms.2018.78653 article EN cc-by-nc-sa Archives of Medical Science 2018-12-17

Haemophilia A and B are rarely occurring X chromosome-linked congenital coagulation disorders dominated by spontaneous joint bleedings chronic synovitis, leading to development of haemophilic arthropathy (HA). Progranulin (PGRN) is a growth factor with anti-inflammatory immunomodulatory properties. PGRN an important molecule in the pathogenesis osteoarthritis (OA) rheumatological disorders. This study was aimed at investigating potential role mechanisms underlying HA. The serum levels were...

10.1111/1440-1681.13054 article EN Clinical and Experimental Pharmacology and Physiology 2018-11-29

Background. Assessment of thromboembolic risk is crucial in choosing appropriate treatment atrial fibrillation (AF). Current guidelines recommend basing the decision on CHA2DS2-VASc score. However, score based only clinical parameters and therefore its relationship with laboratory-assessed coagulation status might not always be objective.Objectives. The aim this study was to assess if associated blood AF patients.Material Methods. Patients continuous prequalified for catheter ablation were...

10.17219/acem/104557 article EN cc-by-nc-nd Advances in Clinical and Experimental Medicine 2019-10-07

Abstract Osteoarthritis (OA) is a common medical problem leading to chronic pain and physical disability among the world’s population. Analyzing molecular background of degenerative arthritis creates potential for developing novel targeted methods treatment. Fifty samples meniscus, anterior cruciate ligaments (ACLs) articular surfaces were collected from patients who underwent total knee arthroplasty in 2016. Enzyme-linked immunosorbent assay was used assess levels interleukin (IL)-1β, IL-6,...

10.1515/med-2020-0402 article EN cc-by Open Medicine 2020-01-01

Musculoskeletal disorders affect 20%–33% of all the global population, and its prevalence is continually increasing. According to World Health Organisation, persistent neck pain (NP) currently one leading causes disability. Therefore, assessment effectiveness treatment methods severity disease a necessity. However, due multiplicity clinical tools used different inconsistent scoring between researchers, some inaccuracies may arise. This review article an up-to-date overview that provides...

10.1080/10833196.2020.1814124 article EN Physical Therapy Reviews 2020-09-14
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