About
Contact & Profiles
A5027724613
Research Areas
- Cytomegalovirus and herpesvirus research
- HIV Research and Treatment
- Immune Cell Function and Interaction
University of Colorado Denver
2021
SAMHD1 is a potent HIV-1 restriction factor that blocks reverse transcription in monocytes, dendritic cells and resting CD4+ T by decreasing intracellular dNTP pools. However, may diminish innate immune sensing Ag presentation, resulting weaker adaptive response. To date, the role of on antiretroviral immunity remains unclear, as mouse had no impact murine retrovirus replication prior vivo studies. Here, we show significantly inhibits acute Friend infection mice. Pretreatment with LPS,...
10.4049/jimmunol.2001389
article
EN
The Journal of Immunology
2021-12-10
Coming Soon ...