A5101788553- Cleft Lip and Palate Research
- Craniofacial Disorders and Treatments
- Reconstructive Facial Surgery Techniques
- Facial Trauma and Fracture Management
- Reconstructive Surgery and Microvascular Techniques
- Cardiac electrophysiology and arrhythmias
- Nasal Surgery and Airway Studies
- Facial Nerve Paralysis Treatment and Research
- Tracheal and airway disorders
- Facial Rejuvenation and Surgery Techniques
- Head and Neck Surgical Oncology
- Cardiovascular Function and Risk Factors
- Wound Healing and Treatments
- Dental Implant Techniques and Outcomes
- Orthodontics and Dentofacial Orthopedics
- Bone Tissue Engineering Materials
- Cardiac Arrhythmias and Treatments
- Orthopedic Surgery and Rehabilitation
- Heart Rate Variability and Autonomic Control
- Body Contouring and Surgery
- Temporomandibular Joint Disorders
- Spinal Fractures and Fixation Techniques
- Receptor Mechanisms and Signaling
- Dermatologic Treatments and Research
- Cancer, Lipids, and Metabolism
Korea University
1989-2025
Korea University Medical Center
2015-2024
Asan Medical Center
2020-2023
Ulsan College
2020-2023
University of Ulsan
2020-2023
Convergence
2022
Eastman Chemical Company (Germany)
2022
Tufts Medical Center
2006-2017
Tufts University
2008-2017
McCrone Research Institute
2014
Angiogenesis is implicated in the pathogenesis of cancer, rheumatoid arthritis, and atherosclerosis treatment coronary artery peripheral vascular disease. Here, cholesterol-lowering agents, 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase inhibitors, are shown to interfere with angiogenesis. In vivo, HMG-CoA inhibitor simvastatin dose-dependently inhibited capillary growth both endothelial factor–stimulated chick chorioallantoic membranes basic fibroblast mouse corneas. vitro,...
Parasympathetic stimulation of the heart, which provides protection from arrhythmias and sudden death, involves activation G protein–coupled inward rectifying K+ channel GIRK1/4 results in an acetylcholine-sensitive current, IKACh. We describe a unique relationship between lipid homeostasis, lipid-sensitive transcription factor SREBP-1, regulation cardiac parasympathetic response, development ventricular arrhythmia. In embryonic chick atrial myocytes, lowering by culture lipoprotein-depleted...
(1) Background: In the present study, we evaluated efficacy of a 3D-printed, patient-specific polycaprolactone/beta tricalcium phosphate (PCL/β-TCP) scaffold in treatment complex zygomatico-maxillary defects. (2) Methods: We eight patients who underwent immediate or delayed maxillary reconstruction with PCL implants between December 2019 and June 2021. The these techniques was assessed using volume density analysis computed tomography data obtained before surgery six months after surgery....
Objectives.— To determine the 1‐year prevalence of headache and clinical characteristics primary headaches among school children in South Korea. Background.— Many population‐based studies have estimated headache, migraine, tension‐type (TTH). The results those vary terms race region. There been few epidemiological adolescents Methods.— We conducted a cross‐sectional school‐based study randomized proportional sample 5360 boys girls. All 180 sampled schools participated this study....
Background: The surgery-first orthognathic approach has been applied at our institution since 2007. However, its indications remain debated. aim of this study was to investigate the reliability correct facial asymmetry compared traditional orthodontics-first using a novel artificial intelligence–based cephalometric analysis. Methods: Intervention outcomes ( n = 33) and 26) approaches were examined. Patients with who had undergone surgery from January 2006 2019 included in study. In approach,...
An unfolded helix is an auricular deformity that has garnered relatively little research focus. This study introduces a surgical technique designed to correct flat deformities. A 22-year-old male with bilateral helixes and prominent ears underwent this procedure under local anesthesia. The surgery employed posterior approach, incisions extending from the upper pole of ear concha. Along helical rim, four radiating were made, followed by oblique cuts in cartilage creation triangular flaps...
The materials used for cosmetic procedures by physicians as well illegally non-medical personnel can cause non-thrombotic pulmonary embolism (NTPE). case history is presented of a woman with acute respiratory failure after an illegal vaginal procedure using hyaluronic acid (HA) dermal filler unlicensed medical practitioner on the day symptom onset. Histopathological examination video-assisted thoracoscopic lung biopsy specimen showed granulomatous foreign body reaction multinucleated giant...
Polycaprolactone (PCL) implants are a biodegradable polymeric material with appropriate mechanical strength and durability for use in cranioplasty. They can be manufactured as patient- customized using three-dimensional (3D) printer. Herein, the authors aimed to share our experience cranioplasty of patients deformed asymmetric skulls PCL/beta- tricalcium phosphate (ß-TCP) implants.Seven underwent patient-specific PCL/ß-TCP implants. Cranial computed tomography images were converted 3D model...
When performing lymphovenous anastomosis, it is sometimes difficult to find venules in the proximity of an ideal lymphatic vessel that have a similar diameter vessel. In this situation, larger can be used.The authors evaluated efficacy and patient satisfaction with bypass sleeve-in anastomosis. Between January 2014 December 2016, we performed procedure 18 patients (eight upper extremities 10 lower extremities) secondary lymphedema. Lymphovenous anastomosis was under microscopy after...
Although a reduction in the high-frequency (HF) component of heart rate variability (HRV) is major complication diabetes and risk factor for sudden death, its relationship to ventricular tachycardia (VT) unknown. We developed mouse model study VT changes HRV Akita type 1 diabetic mouse. Programmed stimulation anesthetized mice demonstrated that were more inducible compared with wild-type mice: 78.6% versus 28.6% (P = 0.007). Optical mapping perfused hearts multifocal breakthroughs...
Decreased heart rate variability (HRV) is a major risk factor for sudden death and cardiovascular disease. We previously demonstrated that parasympathetic dysfunction in the of Akita type 1 diabetic mouse was due to decrease level sterol response element–binding protein (SREBP-1). Here we demonstrate hyperactivity glycogen synthase kinase-3β (GSK3β) atrium results decreased SREBP-1, attenuation modulation rate, measured as high-frequency (HF) fraction HRV presence propranolol, expression...
Facial paralysis is a devastating disease, the treatment of which challenging. The use masseteric nerve in facial reanimation has become increasingly popular and been applied to an expanded range clinical scenarios. However, appropriate selection motor method vital for successful reanimation. In this literature review on masseter nerve, we summarize compare various methods using nerve. can be used direct coaptation with paralyzed temporary input during cross-facial graft regeneration double...
Abstract: Scalp defects of various etiologies require distinct reconstruction strategies. Therefore, the authors divided scalp into following categories: scar alopecia, open wound, benign or low-grade malignant tumor, and high-grade malignancy. The reviewed experience with a single center to determine factors that affect reconstructive choices. Patients who underwent between 2008 2020 were retrospectively reviewed. Reconstruction methods classified according etiology defect compared for each...
Open reduction and internal fixation (OR/IF) closed treatments are viable options, with OR/IF gaining popularity in mandibular condylar head fracture (CHF). Sufficient research is lacking on long-term morphologic changes. This study quantitatively evaluated the changes patients who underwent for CHF without removal of osteosynthesis material. A retrospective analyzed between November 2010 August 2022. The transverse/lateral condyle width height were radiologically using panoramic reverse...
Background The survival rate of grafted fat is difficult to predict, and repeated procedures are frequently required. In this study, the effects freezing period harvested adipose tissue addition human tissue-derived stem cells (ASCs) on process absorption were studied. Methods Adipose was obtained from patients who underwent a lipoaspirated graft. cryopreserved at -20℃ in domestic refrigerator. A total 40 nude mice used. experimental group received three different subcutaneous injections...
The surgical correction of unilateral coronal synostosis (UCS) aims to achieve longstanding facial and cranial symmetry. authors hypothesized that endocranial morphology achieved by one-piece fronto-orbital advancement with distraction osteogenesis (FODO) could alleviate asymmetry because is thought be its major determinant. This study aimed quantitatively analyze the changes in supraorbital midfacial symmetry after FODO.The included 27 patients UCS who underwent FODO between May 2008...
Abstract Background This study aimed to explore the outcomes of motor‐innervated free flaps in hemi‐tongue reconstruction by assessing tongue mobility through midsagittal images from cine‐magnetic resonance imaging. Methods In this retrospective study, 47 patients who underwent following hemi‐glossectomy and 10 control subjects without any surgical history were included. Patients classified into two groups: motor no‐motor innervation group. Various spatial parameters related that acquired...
Poly-L-lactide materials combined with hydroxyapatite (u-HA /PLLA) have been developed to overcome the drawbacks of absorbable materials, such as radiolucency and comparably less implant strength. This study was designed evaluate usefulness u-HA/PLLA material in repair orbital medial wall defects.This included 10 patients pure blow-out fractures. The plain radiographs were taken preoperatively, immediately after, 2 months after surgery. computed tomography scans performed preoperatively...
This study aimed to propose a novel surgical technique, named multiple tangential shaving of bone contour, for the conservative management craniofacial fibrous dysplasia. We retrospectively reviewed 17 patients who underwent dysplasia using technique between July 2005 and December 2020. Demographics, tumor characteristics, surgery-related factors were investigated. All preoperative (T0) postoperative computed tomography scans taken at least twice within 1 month immediate assessment (T1) 12...