A5022020577- Developmental Biology and Gene Regulation
- Marine Ecology and Invasive Species
- Marine Biology and Ecology Research
- Marine Invertebrate Physiology and Ecology
- Marine Biology and Environmental Chemistry
- Marine and coastal plant biology
- Protist diversity and phylogeny
- Planarian Biology and Electrostimulation
- Echinoderm biology and ecology
- Cancer-related molecular mechanisms research
- Animal Genetics and Reproduction
- Parasite Biology and Host Interactions
- RNA Research and Splicing
- Congenital heart defects research
- Hedgehog Signaling Pathway Studies
- Protein Tyrosine Phosphatases
- interferon and immune responses
- Reproductive biology and impacts on aquatic species
- Identification and Quantification in Food
- Silk-based biomaterials and applications
- MicroRNA in disease regulation
- Crustacean biology and ecology
- Environmental DNA in Biodiversity Studies
- bioluminescence and chemiluminescence research
- Ubiquitin and proteasome pathways
St Petersburg University
2012-2024
Zoological Institute
2021-2022
Hox genes are the key determinants of different morphogenetic events in all bilaterian animals. These probably responsible for maintenance regenerative capacities by providing positional information regenerating animal body. Polychaetes well known their ability to regenerate posterior as anterior part We have recently described expression 10 out 11 during postlarval growth Alitta (Nereis) virens. form gradient overlapping patterns, which do not contribute morphological diversity segments...
Hox genes are the family of transcription factors that play a key role in patterning anterior-posterior axis all bilaterian animals. These display clustered organization and colinear expression. Expression boundaries individual usually correspond with morphological body. Previously, we studied gene expression during larval development polychaete Alitta virens (formerly Nereis virens) discovered expressed nereid larva according to spatial colinearity principle. Adult consist multiple...
Abstract Background Transcription factors that encode ANTP-class homeobox genes play crucial roles in determining the body plan organization and specification of different organs tissues bilaterian animals. The three-gene ParaHox family descends from an ancestral gene cluster existed before evolution Bilateria. All three are reported deuterostomes lophotrochozoans, but not to date any ecdysozoan taxa, there is evidence genes, like related Hox were ancestrally a single chromosomal cluster....
Hox genes are some of the best studied developmental control genes. In overwhelming majority bilateral animals, these sequentially activated along main body axis during establishment ground plane, i.e., at moment gastrulation. Their activation is necessary for correct differentiation cell lines, but same time it reduces level stemness. That why chromatin loci in pre-gastrulating embryo a bivalent state. It carries both repressive and permissive epigenetic markers H3 histone residues, leading...
Pygospio elegans Claparède, 1863 is a sedentary tube-dwelling annelid belonging to Spionidae family.Its prominent regeneration abilities, as well its small size, widespread distribution and environmental tolerance make P. perfect model for studying cellular molecular mechanisms of regeneration, larval postlarval growth.Here we performed staging which will be useful future studies the reparation process.We also described some morphological aspects anterior posterior post-traumatic collected...
The evolution of major taxa is often associated with the emergence new gene families. In all multicellular animals except sponges and comb jellies, genomes contain Hox genes, which are crucial regulators development. canonical function genes involves colinear patterning body parts in bilateral animals. This general implemented through complex, precisely coordinated mechanisms, not evolutionarily conserved fully understood. We suggest that this regulatory complexity was preceded by a stage...
The evolution of major taxa is often associated with the emergence new gene families. In all multicellular animals except sponges and comb jellies, genomes contain Hox genes, which are crucial regulators development. canonical function genes involves collinear patterning body parts in bilateral animals. This general implemented through complex, precisely coordinated mechanisms, not evolutionarily conserved fully understood. We suggest that this regulatory complexity was preceded by a stage...
The neural tube of amniotes is formed through different mechanisms that take place in the anterior and posterior regions involve plate folding or mesenchymal condensation followed by its cavitation. Meanwhile, teleost trunk region, forms keel, while lumen develops later. However, data on neurulation other morphogenetic processes body region Teleostei remain fragmentary. We proposed there could be variations processes, such as cell shape changes rearrangements, compared to one at stages....
Abstract To date it is becoming more and obvious that multiple non-coding RNAs, once considered to be transcriptional noise, play a huge role in gene regulation during animal ontogenesis. Hox genes are key regulators of embryonic development, growth regeneration all bilaterian animals. It was shown mammalian loci transcribed both directions noncoding RNAs maintain control the normal functioning clusters. We revealed antisense transcripts most two lophotrochozoans, errant annelids Alitta...