A5050172066- Plant Stress Responses and Tolerance
- Fungal Infections and Studies
- Antifungal resistance and susceptibility
- Genetic and Environmental Crop Studies
- Genomics and Phylogenetic Studies
- Chromosomal and Genetic Variations
- Botanical Research and Chemistry
- Metal-Catalyzed Oxygenation Mechanisms
- Fiscal Policy and Economic Growth
- Fungal and yeast genetics research
- Cholinesterase and Neurodegenerative Diseases
- Metabolomics and Mass Spectrometry Studies
- Information and Cyber Security
- Taxation and Compliance Studies
- Law, AI, and Intellectual Property
- Genomics and Chromatin Dynamics
- Privacy-Preserving Technologies in Data
- Metalloenzymes and iron-sulfur proteins
- Botanical Research and Applications
- Bacterial biofilms and quorum sensing
- Microtubule and mitosis dynamics
- Fungal Biology and Applications
- Force Microscopy Techniques and Applications
- Nail Diseases and Treatments
- Algal biology and biofuel production
National Institute of Plant Genome Research
2022-2024
Indian Institute of Technology Roorkee
2017-2024
Seva Mandir
2017-2018
Cryptococcosis is an emerging and recalcitrant systemic infection occurring in immunocompromised patients. This invasive fungal difficult to treat due the ability of Cryptococcus neoformans laurentii form biofilms resistant standard antifungal treatment. The toxicity concern these drugs has stimulated search for natural therapeutic alternatives. Essential oil their active components (EO-ACs) have shown possess variety biological pharmacological properties. In present investigation effect six...
Harnessing the halotolerant characteristics of microalgae provides a viable alternative for sustainable biomass and triacylglyceride (TAG) production. Scenedesmus sp. IITRIND2 is fast growing fresh water microalga that has capability to thrive in high saline environments. To understand microalga's adaptability, we studied its physiological metabolic flexibility by studying differential protein, metabolite lipid expression profiles using metabolomics, proteomics, real-time polymerase chain...
The recalcitrant biofilm formed by fungus Cryptococcus neoformans is a life-threatening pathogenic condition responsible for further intensifying cryptococcosis. Considering the enhanced resistance and toxicity of synthetic antifungal drugs, search efficient, nontoxic, cost-effective natural therapeutics has received major boost. Phenolic (thymol carvacrol) aldehydic (citral) terpenes are safe alternatives capable efficient microbial inhibition. However, inhibition mechanism these still...
Candida tropicalis is an emerging non-albicans species which pathogenic to the immune-compromised humans, especially in tropical countries, including India. The acquired resistance of towards antifungal therapies major concern. Moreover, limited efficacy and dosage constraint synthetic drugs have indicated prerequisite finding new natural for treatment. In present study, we compared influence citral thymol on C. its biofilm along with expression levels certain tolerance genes. anti-biofilm...
Abstract Cicer arietinum , Cajanus cajan Vigna radiata and Phaseolus vulgaris are economically important legume crops with high nutritional value. They negatively impacted globally by different biotic abiotic stresses. Hyperosmolality-gated calcium-permeable channels (OSCA) have been characterized as osmosensors in Arabidopsis thaliana but not previously reported legumes. This study provides a genome-wide identification, characterization, comparative analysis of OSCA genes Our identified 13...
Candida tropicalis is an opportunistic human pathogen with ability to cause superficial as well systemic infections in immunocompromised patients. C. biofilms can persistent which are difficult treat due acquired resistance. Citral has been used antifungal agents against species and biofilms. In the present study, we one-dimensional polyacrylamide gel electrophoresis (1D-PAGE) matrix-assisted laser desorption ionization-time of flight mass spectrometry (MALDI-TOF/TOF-MS) identify changes...
<title>Abstract</title> <bold>Background</bold> Fusion transcripts (FTs), generated by the fusion of genes at DNA level or RNA-level splicing events significantly contribute to transcriptome diversity. FTs are usually considered unique features neoplasia and serve as biomarkers therapeutic targets for multiple cancers. The latest findings show presence in normal human physiology. Several discreet reports mentioned planta, has important roles stress responses, morphological alterations,...
Abstract The environmental stress is jeopardizing the production as well survival of plants. This leads to emergence ROS, a toxic byproduct several metabolic processes. To combat ROS plant possess definite defense machinery, superoxide dismutase one antioxidant enzymes responsible for effectively eradicating these ROS. Amongst SOD, MnSOD specialized in eliminating from mitochondria, site cellular energy production. In this study, 16 plants was considered, and its physiochemical structural...
Abstract Cicer arietinum , Cajanus cajan Vigna radiata and Phaseolus vulgaris are economically important legume crops with high nutritional value. They negatively impacted globally by different biotic abiotic stresses. Hyperosmolality-gated calcium-permeable channels (OSCA) have been characterized as osmosensors in Arabidopsis thaliana but not previously reported legumes. This study provides a genome-wide identification, characterization comparative analysis of OSCA genes Our identified 13...