A5023811173- Moringa oleifera research and applications
- Drug-Induced Hepatotoxicity and Protection
- Adipose Tissue and Metabolism
- Chemotherapy-induced organ toxicity mitigation
- Retinoids in leukemia and cellular processes
- Sperm and Testicular Function
- Antioxidant Activity and Oxidative Stress
- Animal Nutrition and Physiology
- Male Reproductive Health Studies
- Biochemical Analysis and Sensing Techniques
- Liver Disease Diagnosis and Treatment
- Phytochemicals and Antioxidant Activities
- Heavy Metal Exposure and Toxicity
- Garlic and Onion Studies
- Natural Antidiabetic Agents Studies
- Regulation of Appetite and Obesity
- Ginseng Biological Effects and Applications
- Liver Disease and Transplantation
- Synthesis and bioactivity of alkaloids
- Fatty Acid Research and Health
- Muscle metabolism and nutrition
- Peroxisome Proliferator-Activated Receptors
- Nanoparticles: synthesis and applications
- Adipokines, Inflammation, and Metabolic Diseases
- Pharmacological Effects of Natural Compounds
Menoufia University
2012-2025
Government of Uttar Pradesh
2022
John Wiley & Sons (United States)
2022
Kyoto University
2016-2020
Hokkaido University
2007-2017
Aswan University
2017
University of Sadat City
2013-2016
The current study was carried out to evaluate the ameliorative effect of fucoidan against aflatoxicosis-induced hepatorenal toxicity in streptozotocin-induced diabetic rats. Sixty-four Wister albino male rats were randomly assigned into eight groups (8 each) that received normal saline, (FUC) at 100 mg/kg/day orally for 4 weeks, streptozotocin (STZ) 50 mg/kg/i.p. single dose, STZ plus FUC, aflatoxin B1 (AFB1) μg/kg/i.p. after one month beginning experiment 2 AFB1 AFB1, or and FUC. Injection...
Acrylamide is a hazardous substance inducing oxidative stress. Based on some evidence the antioxidant properties of fenugreek, Trigonella foenum-graecum, this study was conducted to investigate protective effect fenugreek seed oil against acrylamide toxicity. Thirty-two male Wistar rats were randomly assigned into four groups. The control group given normal saline. second administered (20 mg/kg bw orally). third and fourth groups bw) supplemented with 2.5% 5% in their diets, respectively....
The objective of this study was to investigate the effects Spirulina platensis powder (SPP) supplementation on growth performance, antioxidative status and blood metabolites in fattening lambs. Ten healthy lambs (46.5 ± 1.06 kg BW) were randomly assigned one two treatments (5 per treatment) received either no or supplemented with SPP at a rate 1 g/10 BW/day. feeding experiment conducted for 35 days body weight recorded samples collected 0, 17 experiment. paired Student's t-test means used...
This study was designed to evaluate protective effect of Saussurea lappa root aqueous extract against Ethephon (2-chloroethylphosphonic acid)-induced reproductive toxicity in rats. Control group received distilled water. Second given S. at a dose 50 mg/kg bw. Third 200 Fourth, fifth, and sixth groups were before, with or after administration, respectively. intoxication significantly decreased serum levels follicle stimulating hormone, luteinizing testosterone, prolactin. Also, it sperms...
This study evaluated the neuroprotective potential of Allium sativum against monosodium glutamate (MSG)-induced neurotoxicity with respect to its impact on short-term memory in rats. Forty male Wistar albino rats were assigned into four groups. The control group received distilled water. second was administered powder (200 mg/kg body weight) orally for 7 successive days, then left without treatment until 30th day. third injected intraperitoneally MSG (4 g/kg fourth same manner as and treated...
Moringa oleifera Lam. contains many active ingredients with nutritional and medicinal values. It is commonly used in folk medicine as an antidiabetic agent. The present study was designed to investigate how aqueous extract from the leaves of M. reveals hypoglycemia diabetic rats. leaf counteracted alloxan-induced effects rats it normalized elevated serum levels glucose, triglycerides, cholesterol, malondialdehyde, mRNA expression gluconeogenic enzyme pyruvate carboxylase hepatic tissues....
Trigonella foenum-graecum L. is enriched with many active ingredients. TFG oil was evaluated for its protective effect against deltamethrin toxicity in rats. Rats of the control group were administered saline. The 2nd (DLM) orally at a concentration 15 mg/kg body mass. 3rd and 4th groups DLM mass fed diets containing 2.5% 5% oil, respectively. intoxication reduced red blood cell platelet counts, hemoglobin concentration, hematocrit value while it induced leucocytosis. Furthermore, increased...
The current study was carried out to evaluate the protective effect of grape seed proanthocyanidins extract (GSPE) against Ehrlich solid tumor (EST) induced renal injury, with respect DNA fragmentation and P53 PCNA proteins expression in tissue. A total 50 female mice were randomly assigned into five groups. Control injected physiological saline solution. Mice 2nd group administered GSPE (50 mg/kg bw/every 2day/per OS) for 2 weeks 3rd subcutaneously 2.5 million cells EAC/mouse. 4th EAC as...
Introduction: Copper oxide nanoparticles (CuO-NPs) are widely used as feed additives for livestock and poultry implicated in many biomedical applications; however, overload of copper NPs induces various toxicological changes dysfunction animal's organs. Thus, this study was designed to evaluate the comparative effects biologically chemically synthesized CuO-NPs on mice. Methods: Transmission electron microscopy (TEM), X-ray diffraction (XRD) Fourier-transform infrared spectroscopy (FT-IR)...
This study evaluates the antitumor efficacy of hesperidin (Hesp) versus cisplatin (Cis) in Ehrlich ascites carcinoma (EAC)-bearing mice, as well its protective effect against Cis-triggered nephrotoxicity. Seventy female mice were allocated into control, Hesp, EAC, Hesp-protected, Hesp-treated, Cis-treated, and Cis+Hesp-treated groups. The inoculation with EAC cells significantly reduced mean survival time, while increased body weight, abdominal circumference, ascitic fluid volume, viable...
Background: Liver fibrosis represents a serious risk to global health by impairing quality of life and elevating the chances hepatocellular carcinoma, while intricate role autophagy can either alleviate or worsen depending on its functioning. Objective: Herein, we aimed investigate therapeutic effect chlorogenic acid in CCl4-induced hepatic explore pathway as possible molecular target acid. Methods: Rats were injected with carbon tetrachloride (1ml/kg) induce liver for 10 weeks. In current...
This study was carried out to evaluate the possible mechanisms through which an aqueous extract from MO leaves demonstrates hepatoprotective effects in alloxan-induced diabetic rats. Eighty albino rats were assigned 4 groups. The control group orally administered sterile saline. second injected with alloxan (150 mg/kg body mass (b.m.)) by intraperitoneal injection (i.p.). third given (250 b.m.) orally, daily. fourth alloxan, as for group, and administrated of leaves, group. Alloxan induced...
The current study investigated the protective potential of Azolla pinnate ethanolic extract (APE) against lead-induced hepatotoxicity in rats. Sixty male Wistar albino rats were randomly allocated into six groups (n = 10). control group was orally administrated with saline. second received lead acetate (100 mg/kg body weight (BW) for 60 days). third fed APE (10 BW fourth like and group, concomitantly, days. fifth 30 days, then another sixth a further Phytochemical analysis indicated presence...
This study was carried out to illustrate seroprevalence of Toxoplasma gondii and Brucella melitensis in local sheep goat flocks living Nile Delta regions Egypt as well investigate its effects on animals' health performance. In trial 1: 492 serum samples were collected from domestic ewes does suffering abortion stillbirths used this survey. (2): 100 toxoplasma or brucella infected non goats the toxoplasmosis brucellosis animals, health. revealed that 142 (28.86%) sera contained antibodies...
This study was performed to evaluate anti-obesity potential of Commiphora myrrha resin ethanolic extract (CME) with the respect expression leptin, adiponectin and uncoupling protein 1 (UCP1) in rats. Control rats fed basal diet. Second group diet administered CME (500 mg/kg bw) orally for 14 weeks. Third high fat (HFD) Fourth HFD as second group. Fifth 8 weeks then third another 6 Phytochemical analysis identified presence germacrene B, 1,4-benzoquinone, benzofuran, hexadecanoic acid,...
Ceratonia siliqua (Carob) is an evergreen Mediterranean tree, and carob pods are potentially nutritive have medicinal value. The present study was carried out to estimate the possible biological activities of phytochemical-characterized pod aqueous extract (CPAE). phytochemical contents CPAE were determined by using colorimetric methods HPLC. In addition, free radical scavenging properties anti-diabetic, anti-hemolytic, antimicrobial estimated standardized in vitro protocols. analysis...