A5082809165- Organic Chemistry Cycloaddition Reactions
- Chemical Reaction Mechanisms
- Synthesis and Catalytic Reactions
- Chemistry and Chemical Engineering
- Chemical Synthesis and Reactions
- Porphyrin and Phthalocyanine Chemistry
- X-ray Diffraction in Crystallography
- Crystallization and Solubility Studies
- Oxidative Organic Chemistry Reactions
- Chemical Synthesis and Analysis
- Biopolymer Synthesis and Applications
- Enzyme Structure and Function
- Free Radicals and Antioxidants
- Carbon dioxide utilization in catalysis
- Fluorine in Organic Chemistry
- Amino Acid Enzymes and Metabolism
- Lanthanide and Transition Metal Complexes
- Chemical Reactions and Isotopes
- Organometallic Complex Synthesis and Catalysis
- Inorganic and Organometallic Chemistry
- CO2 Reduction Techniques and Catalysts
- Advanced Chemical Physics Studies
- biodegradable polymer synthesis and properties
- Advanced Photocatalysis Techniques
- Microtubule and mitosis dynamics
AstraZeneca (United Kingdom)
2025
Institute for the Chemistry of OrganoMetallic Compounds
2015-2024
University of Bari Aldo Moro
2012-2022
University of Trieste
2015
Brown University
2001-2011
University of Pavia
2008
Bielefeld University
1994
University of Padua
1994
United States Nuclear Regulatory Commission
1994
Consejo Superior de Investigaciones Científicas
1993
ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTOxidations by methyl(trifluoromethyl)dioxirane. 2. Oxyfunctionalization of saturated hydrocarbonsRossella Mello, Michele Fiorentino, Caterina Fusco, and Ruggero CurciCite this: J. Am. Chem. Soc. 1989, 111, 17, 6749–6757Publication Date (Print):August 1, 1989Publication History Published online1 May 2002Published inissue 1 August 1989https://pubs.acs.org/doi/10.1021/ja00199a039https://doi.org/10.1021/ja00199a039research-articleACS...
The design of efficient and general methods for the selective oxyfunctionalization unactivated carbon−hydrogen bonds continues to represent a major challenge community chemists, despite fact that oxidation alkanes is feature chemical economy. A low level selectivity characteristic large-scale hydrocarbons performed under customary industrial oxidizing conditions (e.g., catalytic air cycloalkanes); in these processes, difficult control, because they are often impacted by usual problems...
Composite materials prepared by loading polycrystalline TiO2 powders with lipophilic highly branched Cu(II)- and metal-free phthalocyanines or porphyrins, which have been used in the past as photocatalysts for photodegradative processes, successfully tested efficient photoreduction of carbon dioxide aqueous suspension affording significant amounts formic acid. The results indicated that presence sensitizers is beneficial photoactivity, confirming important role Cu(II) co-ordinated middle...
ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTOxidations by methyl(trifluoromethyl)dioxirane. 5. Conversion of alcohols into carbonyl compoundsRossella Mello, Luigi Cassidei, Michele Fiorentino, Caterina Fusco, Walter Huemmer, Volker Jaeger, and Ruggero CurciCite this: J. Am. Chem. Soc. 1991, 113, 6, 2205–2208Publication Date (Print):March 1, 1991Publication History Published online1 May 2002Published inissue 1 March 1991https://doi.org/10.1021/ja00006a044Request reuse permissionsArticle...
Nicotinamide N-methyl transferase (NNMT) is involved in the regulation of cellular nicotinamide adenine dinucleotide (NAD) and S-Adenosyl-L-methionine (SAM) levels has been implicated a range human diseases. Herein, we show that class NNMT inhibitors; analogues natural substrate (NAM) are turned over by enzyme methylated product potent inhibitor enzyme. The is, however, charged modest potency. Utilizing this on-target biotransformation combines cell permeability with high potency results...
Abstract The dimethyldioxirane oxidation of α‐methylstyrene, trans ‐cyclo‐octene, and 1‐vinyl‐2,2‐diphenylcyclopropane gave, under all reaction conditions employed, the corresponding epoxides in high yields. No radical products from allylic oxidation, trans/cis isomerization, or cyclopropylcarbinyl rearrangement (radical clock) were observed. Even for these alkenes, which are prone to reactions, previously established electrophilic concerted mechanism applies, rather than recently proposed...
A new protocol for biodiesel production is proposed, based on a binary ZnO/TBAI (TBAI = tetrabutylammonium iodide) catalytic system. Zinc oxide acts as heterogeneous, bifunctional Lewis acid/base catalyst, while TBAI plays the role of phase transfer agent. Being composed by bulk form powders, whole catalyst system proved to be easy use, without requiring nano-structuration or tedious and costly preparation pre-activation procedures. In addition, due amphoteric properties ZnO, can...
ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTOxyfunctionalization of Nonnatural Targets by Dioxiranes. Selective Oxidation CentropolyindansDietmar Kuck, Andreas Schuster, Caterina Fusco, Michele Fiorentino, and Ruggero CurciCite this: J. Am. Chem. Soc. 1994, 116, 6, 2375–2381Publication Date (Print):March 1, 1994Publication History Published online1 May 2002Published inissue 1 March 1994https://doi.org/10.1021/ja00085a017Request reuse permissionsArticle Views376Altmetric-Citations56LEARN...
ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTSelective oxidation of optically active sec,sec-1,2-diols by dioxiranes. A practical method for the synthesis homochiral .alpha.-hydroxy ketones in high optical purityLucia D'Accolti, Antonia Detomaso, Caterina Fusco, Angela Rosa, and Ruggero CurciCite this: J. Org. Chem. 1993, 58, 14, 3600–3601Publication Date (Print):July 1, 1993Publication History Published online1 May 2002Published inissue 1 July...
Silicon nanowires (SiNWs) decorated by pulsed laser ablation with gold or copper nanoparticles (labeled as AuNPs@SiNWs and CuNPs@SiNWs) were investigated for their catalytic properties. Results demonstrated high performances in the Caryl-N couplings subsequent carbonylations catalysts, respectively, that have no precedents literature. The excellent activity, attested very turn over number (TON) values, was due both to uniform coverage along NW length absence of chemical shell surrounding...
Dioxiranes are powerful oxidants that can act via two different mechanisms: 1) homolytic (H abstraction and oxygen rebound) 2) heterolytic (electrophilic oxidation). So far, it has been reported the nature of substrate dictates reaction mode independently from dioxirane employed. Herein, we report an unprecedented case in which rules oxidation chemoselectivity. In particular, a switch C-H to N-H is observed lactams moving dimethyl (DDO) methyl(trifluoromethyl)dioxirane (TFDO). A physical...
The challenging hypothesis of a "biphilic" (i.e., electrophilic vs nucleophilic) character for dioxirane reactivity, which envisages that electron-poor alkenes are attacked by dioxiranes in nucleophilic fashion, could not be sustained experimentally. Rate data, estimate Hammett "rho" values the epoxidation 3- or 4-substituted cinnamonitriles X x Ph-CH=CH-CN, unequivocally allow one to establish epoxidize electrophilically even carrying electron-withdrawing groups. greater propensity...
Following our pioneering studies on the direct and efficient introduction of derivatizable hydroxyl handles into valinomycin (VLM, 1) structure, a K(+)-ionophore with potent antitumor activity, ensuing conjugable analogues (HyVLMs 2, 3, 4) have herein been compared to parent macrocycle for their potential antiproliferative effects panel cancer cell lines, namely, human MCF-7, A2780, HepG2, as well rat C6 cells. On basis IC50 values, we find that 3 4 are only moderately less active than 1,...
Abstract Organic functionalization of carbon nanotube sidewalls is a tool primary importance in material science and nanotechnology, equally from fundamental an applicative point view. In this paper, mild easily tunable approach to the sidewall decoration single‐walled nanotubes (SWCNTs) with epoxides their subsequent derivatization (ring opening) upon treatment reactive nucleophiles presented. The HiPco purified SWCNTs dioxirane solutions results highly oxidized CNTs, which are used as...
A two-phase extraction process was adopted to obtain cellulose and hemicellulose from buckwheat chaff by using green solvents.We are proposing a combination of propylene carbonate (PC) ionic liquids (ILs) in 1:5 ratio.We compared the first-generation ILs 1-butyl-2,3-dimethylimidazolium chloride (BdmimCl), 1butyl-3-methyl imidazolium acetate (BmimAc) with respect tetrabutyl ammonium (TBAAc).The were, firstly, extracted into PC/IL mixture subsequently precipitated water addition.All...
Unprecedented in the literature, levulinic acid (LA), one of top value-added intermediates chemical industry, is obtained from cigarette butts as cellulose feedstock by means a one-pot hydrothermal process carried out at 200 °C for 2 h and catalysed phosphoric acid. The protocol avoids use more aggressive toxic H2SO4 HCl, that are generally employed on several sources (e.g. sludge paper), thus minimizing corrosion phenomena plants. Neither pre-treatment nor specific purification procedure LA...
Abstract Photoreduction of CO 2 with sunlight to produce solar fuels, also named artificial photosynthesis, is considered one the most attractive strategies face challenge reducing greenhouse gases and achieving climate neutrality. Following an approach in line principles circular economy, low-cost catalytic system ( 1 ) based on industrial by-product such as steel slag was assessed, which properly modified nanostructured palladium its surface order make it capable promoting conversion into...