- Atrial Fibrillation Management and Outcomes
- Cardiac Arrhythmias and Treatments
- Cardiac electrophysiology and arrhythmias
- Cardiac pacing and defibrillation studies
- Cardiac tumors and thrombi
- Antiplatelet Therapy and Cardiovascular Diseases
- Cardiac Imaging and Diagnostics
- Venous Thromboembolism Diagnosis and Management
- Cardiovascular Effects of Exercise
- Cardiac Arrest and Resuscitation
- Cardiac Valve Diseases and Treatments
- ECG Monitoring and Analysis
- Cardiac Structural Anomalies and Repair
- Eosinophilic Disorders and Syndromes
- Computational Drug Discovery Methods
- Heat shock proteins research
- Cardiovascular Syncope and Autonomic Disorders
- Appendicitis Diagnosis and Management
- Hernia repair and management
- Drug-Induced Adverse Reactions
- Voice and Speech Disorders
- Intramuscular injections and effects
- Colorectal Cancer Surgical Treatments
- Acute Myocardial Infarction Research
- Infective Endocarditis Diagnosis and Management
Icahn School of Medicine at Mount Sinai
2020-2025
Mount Sinai Hospital
2024-2025
University of Toledo Medical Center
2025
Mount Sinai Hospital
2023-2024
Massachusetts General Hospital
2011-2020
Brown University
2016-2020
Rhode Island Hospital
2020
Providence College
2020
Harvard University
2011-2014
University of Massachusetts Chan Medical School
2011-2012
Abstract Background Echocardiographic left atrial (LA) strain parameters have been associated with fibrillation (AF) in prior studies. Our goal was to determine if measures [peak systolic longitudinal (LAS) and stiffness index (LASt)] changed after cardioversion (CV); their relation AF recurrence. Methods results 46 participants persistent 41 age-matched no were recruited. LAS LASt measured before immediately CV using 2D speckle tracking imaging (2DSI). Maintenance of sinus rhythm assessed...
Azathioprine intolerance is a common clinical problem, requiring drug withdrawal in up to 30% of patients. The successful use mercaptopurine described, but data support this strategy are needed.To assess the tolerability inflammatory bowel disease patients previously intolerant azathioprine, and identify predictive factors.Sixty-one azathioprine-intolerant (31 males, median age at diagnosis 32 years, 31 with Crohn's disease, 30 ulcerative colitis) who had been treated were identified....
Importance It is well appreciated that a small yet high-risk subset of patients with atrial fibrillation (AF) develops persistent left appendage (LAA) thrombus despite optimal oral anticoagulation (OAC). In either heightened risk bleeding precluding enhanced doses OAC to dissolve the thrombus, or thromboembolism OAC, there are limited nonsurgical options. Objectives To introduce novel management strategy for resistant LAA thrombus: percutaneous mechanical aspiration cerebral protection,...
Abstract Background Atrial fibrillation (AF) poses significant risks of stroke and mortality. Catheter ablation (CA) has emerged as a superior rhythm control strategy compared to medical therapy, but its long-term benefits in AF, ischemic prevention, remain underexplored. Methods This observational study analyzed data from the TriNetX Research Network, encompassing over 115 million patients. Adults diagnosed with paroxysmal atrial (PAF) between 2012 2019 were stratified into CA non-CA...
During atrial fibrillation (AF), a high rate of myocyte activation causes cellular stress and initiates the process remodeling, which further promotes persistence AF. Although heat shock proteins (HSPs) have been shown to prevent remodeling suppress occurrence AF in animal experimental models, increased levels HSP-60 observed patients with postoperative AF, likely reflecting response stress. To better understand role relation we examined association future development Multi-Ethnic Study...
Abstract Aims Validating mapping systems that identify atrial fibrillation (AF) sources (focal/rotational activity) is confounded by the absence of ground truth. A key concern prior technologies spatiotemporal instability, manifesting as poor map reproducibility. Electrographic flow (EGF) employs a novel algorithm visualizes electrical wavefront propagation to putative AF sources. We analysed both intra- (3 min) and inter- (>3 months) procedure EGF Methods results In 23 persistent...
Atrial fibrillation (AF) is the most common cardiac arrhythmia encountered in clinical practice, which associated with substantial risk of stroke and thromboembolism. As an that particularly elderly, it important contributor towards morbidity mortality. Ventricular rate control has been a preferred therapeutically convenient treatment strategy for management AF. Recent research field rhythm led to advent newer antiarrhythmic drugs catheter ablation techniques as therapeutic options....