Olga Goryacha

ORCID: 0000-0001-9877-7392
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Research Areas
  • Medicinal plant effects and applications
  • Phytochemistry and Biological Activities
  • Phytochemicals and Antioxidant Activities
  • Natural product bioactivities and synthesis
  • Phytochemical and Pharmacological Studies
  • Food Quality and Safety Studies
  • Pharmacological Effects of Natural Compounds
  • Heavy Metals in Plants
  • Natural Antidiabetic Agents Studies
  • Essential Oils and Antimicrobial Activity
  • Flavonoids in Medical Research
  • Bee Products Chemical Analysis
  • Historical Medical Research and Treatments
  • Botany and Plant Ecology Studies
  • Medical and Pharmaceutic Studies
  • Phytase and its Applications
  • Pharmacological Effects of Medicinal Plants
  • Seaweed-derived Bioactive Compounds
  • Saffron Plant Research Studies
  • Medicinal Plants and Bioactive Compounds
  • Botanical Studies and Applications
  • Agriculture and Biological Studies
  • Medical and Biological Sciences
  • Medicinal Plant Pharmacodynamics Research
  • Fermentation and Sensory Analysis

National University of Pharmacy
2013-2024

University of Tartu
2024

Ivano-Frankivsk National Medical University
2024

Paññāsāstra University of Cambodia
2018

The present article discusses the results of an immunomodulatory activity Galii veri herba, Galium verum herb (Galium L., Rubiaceae) fluid water extract and effect polysaccharide phenolic complexes letter on activity. same was fractionated into a complex (PSC) polyphenolic (PPC). In obtained substances, contents hydroxycinnamic derivates, flavonoids polyphenols were determined spectrophotometrically; polysaccharides quantified gravimetrically; substances in reaction lymphocyte blast...

10.36290/csf.2018.003 article EN Česká a slovenská farmacie 2018-01-01

Extracts from aerial parts of G. aparine (cleavers) constitute a herbal remedy with monography in British Herbal Pharmacopeia. On the European market, there are several drugs and food supplements consisting Galium extracts. In folk medicine, cleavers was used topically Europe, Asia, Americas to treat skin diseases. remedies, is also listed as an immunomodulatory active herb influencing defense response human body. The aim this study investigate immunostimulatory activity antioxidant...

10.3390/molecules25163721 article EN cc-by Molecules 2020-08-14

Aim. To determine the qualitative composition and quantitative content of saponins in liquid extracts herb cleavers (Galium aparine L.) lady's bedstraw verum L.).Materials methods. Extracts were obtained by triple extraction raw material with 96 % ethanol when heating subsequent concentration combined to ratio : finished product 1:1. Saponins studied method high-performance chromatography (HPLC).Results. As a result chromatographic study it has been found that they contain 6 7 saponins,...

10.24959/nphj.18.2225 article EN cc-by News of pharmacy 2018-11-29

Diabetes mellitus is a global medical and social issue. In the developed countries of world, from 5 to 12% population are diagnosed with diabetes and, according WHO prognosis, level this disease may increase 30-35%. Type 2 that progresses over time, but rational systematic use hypoglycemic synthetic drugs phytopreparations can significantly delay onset insulin therapy. A promising source BAS effect raw material plants Heather family, namely, bearberry leaves. However, on Ukrainian market...

10.15587/2519-4852.2021.235939 article EN ScienceRise Pharmaceutical Science 2021-06-30

The present article discusses the results of research into phytochemical profile and immunomodulatory activity Galii veri herba (Galium verum L., Rubiaceae) ethanolic extracts. extracts under study were obtained from plant material by means maceration technique with 20% aqueous ethanol solution (fluid extract I), 60% II) 96% III) on heating. In substances obtained, content hydroxycinnamic derivatives, flavonoids polyphenols determined spectrophotometrically; polysaccharides quantified...

10.36290/csf.2018.014 article EN Česká a slovenská farmacie 2018-03-01

Phenolic compounds of the liquid extract from cleavers herb (Galium aparine L.)Aim.To study qualitative composition and quantitative content phenolic obtained L.) herb.Materials methods.The was by triple extraction raw material with 60 % ethanol when heating, followed concentration combined extracts to ratio : finished product 1 1.The extractives determined gravimetric method.Phenolic were studied methods high-performance chromatography (HPLC) UV-spectrophotometry.Results discussion.In...

10.24959/nphj.18.2213 article EN cc-by News of pharmacy 2018-08-08

The article presents the data of pharmacognostic study aerial part black horehound (Ballota nigra L.). aim work is to determine qualitative composition and quantitative content volatile components from vegetative generative organs horehound. Leaves, flowers stems were harvested at flowering phase in Kharkiv region. For first time compounds parts have been investigated by GC/MS. component substances herb has studied using an Agilent Technologies 6890N chromatograph with a mass spectrometry...

10.24959/nphj.14.1967 article EN cc-by News of pharmacy 2014-06-06

In the Ukrainian flora, species of Veronica L. genus (Plantaginaceae Juss.) are classified into 8 sections. Among representatives Pseudolysimachion W. D. J. Koch section in Kharkiv region, spicata (spike speedwell) and incana (Veronica subsp. (L.) Walters, silver common. Plants used for treatment upper respiratory tract diseases, malignant neoplasms, gastrointestinal genitourinary system disorders, diabetes mellitus.
 The aim research was to study carboxylic acids flowers L.
...

10.15587/2519-4852.2022.253541 article EN ScienceRise Pharmaceutical Science 2022-02-28

Aim: The aim of the study is to elemental composition leafy shoots, rhizomes, and roots D. fruticosa varieties cultivated in Ukraine. Background: Dasiphora (L.) Rybd. ( Rosaceae ) a species native Middle Asia Far East. More than 130 are known; plants have significant raw material base promising objects for phytochemical research. Data only on aboveground parts wild-grown present. No information materials available. Objective: A comprehensive analysis identification features macro-...

10.2174/18743315-v16-e2201240 article EN The Open Agriculture Journal 2022-03-10

In the Ukrainian flora, species of Veronica L. genus (Plantaginaceae Juss.) are classified into 8 sections. The phytochemical research secondary metabolites most related to study phenolic compounds and iridoids, while terponoids these need further research. chemical profiles V. longifolia L., incana spicata flora poorly studied. Phenolic acids, hydroxycinnamic coumarins, flavonoids, tannins, saponins, amino acids organic have been reported for species. Herbs harvested during flowering stage...

10.15587/2519-4852.2022.263735 article EN ScienceRise Pharmaceutical Science 2022-08-29

This historical essay presents an analysis of the origins and development modern pharmacognosy in Ukraine explores founding Department Pharmacognosy at National University Pharmacy (NUPh, Kharkiv), providing overview department`s history, a framework its educational methodological processes, primary research directions, main achievements. The paper also includes biographical data outlines scientific pedagogical achievements prominent individuals who made significant contribution to formation...

10.11590/abhps.2024.2.02 article EN cc-by-nc Acta Baltica Historiae et Philosophiae Scientiarum 2024-12-22

The research presents results of in vitro studies the effect dry extracts Asperula odorata and humifusa on functional activity macrophages their hematogenous precursors. It has been found that studied reveal a dose-dependent stimulatory transformation phagocytic activities mononuclear extract exhibits more expressed immunomodulatory dose range from 5 to 100 μg/ml. When using μg/ml maximal stimulation immune competent cells observed. Therefore, increases by 57%, index is 46% number 54%...

10.24959/cphj.15.1323 article EN cc-by Clinical pharmacy 2015-03-10

The aim. To conduct research on the pharmaceutical development of a complex preparation with probiotic “Probioskin” in form an emulgel for treatment infectious and inflammatory dermatological diseases.
 Methods. Uniformity was determined by visual inspection test samples using XSP-128 ULAB biological microscope. study rheological properties carried out Rheolab QC rheovisosimeter (Anton Paar, Austria) system coaxial cylinders C-CC27 / SS. Microbiological studies biotesting model ciliates...

10.15587/2519-4852.2021.249710 article EN ScienceRise Pharmaceutical Science 2021-12-29
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