Galenic preparations of German chamomile are used to treat mild skin diseases, inflammation, and spasms, they have also been reported anxiolytic sedative effects. The medicinal use is well known in ethnomedicine. After obtaining its galenic preparations, there lots waste left, so it expedient develop waste-free technologies. aims this study were gain knowledge the ethnomedical status past present, methods for preparing essential oils dry extracts from flowers using complex processing, reveal...

Species of the genus Eryngium L. Apiaceae family are successfully used in folk medicine various countries worldwide, but they hardly implemented official medicinal and pharmaceutical practices. Therefore, it is advisable to conduct phytochemical pharmacological research E. planum herb extracts develop implement new phytomedicines based on this raw material. Purified water, 40% 70% ethanol were for obtaining soft extracts. A total seven hydroxycinnamic acids, six flavonoids, three tannin...

The most promising plant from the genus Agrimony (Agrimonia L.) of Rosaceae family for use in medical practice is Agrimonia eupatoria L. Phytochemical and pharmacological research herb extract, obtained with using 40% ethanol solution as an extractant were carried out. A total 11 free 17 bound monosaccharides, amino acids found studied 9 which are essential. Gallic ellagic acids, gallocatechin, epigallocatechin, catechin, epicatechin, epicatechin gallate identified extract A. by HPLC method;...

Overcoming the health threatening consequences of staphylococcal infections and their negative socio-economic effects have become a priority in medical, pharmaceutical, food many other sectors globally. Staphylococcal are big challenge for global care, since they difficult to be diagnosed treated. Therefore, development new medicinal products plant-origin is timely important, because bacteria limited ability develop resistance such products. In present study, modified eucalypt (Eucalyptus...

The prospect of creating a new medicine with psychotropic activity is shown as result studying the chemical composition and pharmacological modified dry extracts motherwort (Leonurus cardiaca L.) tincture. most promising substances were extracts, by adding small amounts arginine, valine, phenylalanine, glycine, lysine, alanine. A total 15 main phenolic found in eight them identified. There also 10 hydroxycinnamic acids these three which identified (chlorogenic, caffeic, rosmarinic acids)....

The aerial parts of Anthemis tinctoria L. and Angelica sylvestris the roots A. have been used as traditional anticancer remedies in Estonian ethnomedicine. aim this study was to investigate content essential oils (by gas chromatography) polyphenolic compounds (using two different methods high performance liquid chromatography-mass spectrometry (HPLC-MS)) both plant species, well vitro anti-cancer effects their methanolic extracts. average (n = 5 samples) yield 0.15%, 0.13%, 0.17%,...

Anxiety disorders are highly prevalent worldwide and can affect people of all ages, genders backgrounds. Much efforts resources have been directed at finding new anxiolytic agents drug delivery systems (DDSs) especially for cancer patients to enhance targeted delivery, reduce adverse effects, provide an analgesic effect. The aim this study was (1) design develop novel nanofiber-based DDSs intended the oral administration 1,2,3-triazolo-1,4-benzodiazepines derivatives, (2) investigate...

Bone defects are becoming a true challenge in global health care due to the aging population and higher prevalence of musculoskeletal disorders. The interest using plant‐origin compounds plant‐derived biomaterials bone tissue engineering (BTE) has been increased their availability (abundance), safety, biocompatibility, biodegradability, low cost. Plant‐origin have supportive effects on healing, cell‐laden can be applied formulating bioinks for three‐dimensional (3D) bioprinting facilitate...

Abstract: Chronic pain lasting more than three months or persisting after normal healing is a significant global health issue. In healthcare system, it crucial to ensure proper chronic management. Traditional pharmacological and non-pharmacological management techniques may not fully meet the requirements of physicians regarding effectiveness safety. Therefore, researchers are exploring natural analgesics. Plant-based phytoconstituents show promise in relieving associated with various...

The genus Ajuga (Lamiaceae family) comprises approximately 300 species, which are widely used in traditional medicine for their diaphoretic, antiseptic, hemostatic, and anti-inflammatory properties, but scarcely official ones. Therefore, the study of reptans holds promise developing new medicinal products. In aqueous aqueous-alcoholic soft extracts A. herb, 16 amino acids, 20 phenolics, 10 volatile substances were identified by HPLC GC/MS. assays main substances' groups also determined...

Flavonoids are a vast class of phenolic substances. To date, there approximately 6000 plant-origin flavonoids discovered, and many them have found uses in drug therapy. Today, therapeutic commonly formulated to conventional “one size fits all” dosage forms, such as immediate-release tablets or hard capsules. The current trend pharmacy medicine, however, is personalized therapy delivery systems (DDSs). Therefore, 3D printing an interesting technique for designing preparing novel...

Bluehead gilia or bluefield (Gilia capitata Sims) from the family Polemoniaceae is an annual herbaceous plant widely distributed in western regions of North America, but cultivated as ornamental flower various to support pollinators. The chemical composition has not been studied before. For first time, essential oil (EO) was obtained by hydrodistillation different parts gilia, harvested Estonia. yield EOs 0.42 1.97 mL/kg, with greatest yields seeds, flowers, fruits, and leaves. Its component...

The key objective of this study was to determine the yield and chemical composition 9 samples common vervain (Verbena officinalis L.) herb essential oil (EO), originating from 7 different countries and, consequently, assess its potential for treating anxiety depression. According GC-MS analysis, 90 compounds were identified, 49 which discovered first time in V. EO. plants with highest content are Greece (4.7 mL/kg) South Carolina, USA (5.2 mL/kg). markers studied chemotypes EO terpenoids...

Background/Objectives: Canadian goldenrod (Solidago canadensis L.) is one of the most widespread species genus Solidago from Asteraceae family. It has a rich composition biologically active compounds and traditionally used to address kidney, urinary tract, liver diseases. Previously, it was proven that S. extract obtained with 40% ethanol solution had promising anti-inflammatory hepatoprotective activity. Therefore, this selected for further formulation amino acids preparations 3D-printed...

Plants of the genus Anemone L. Ranunculaceae family are perennial herbaceous plants. The includes about 200 species, five which growing on territory Ukraine. Despite their relatively wide distribution and availability raw materials, plants this remain insufficiently studied. aim. aim work was to conduct comparative research volatile substances in A. nemorosa ranunculoides materials harvested Materials Methods. Hydrodistillates obtained from dried herb rhizomes were analyzed using gas...

Background/Objectives: The Canadian goldenrod (Solidago canadensis L.) is one of the most widespread species genus Solidago from Asteraceae family. It has a rich composition biologically active compounds and traditionally used to address kidney, urinary tract, liver diseases. Previously, it was proven that S. extract obtained with 40% ethanol solution had promising anti-inflammatory hepatoprotective activity. Therefore, this selected for further formulation amino acid preparations 3D-printed...

Berberine, palmatine, and coptisine are bioactive alkaloids commonly found in medicinal plants, including Coptis chinensis Franch. (Ranunculaceae). To address the limitations of conventional volatile organic solvents, this study employed eco-friendly solvents—aqueous solutions surfactants, carboxylic acids, deep eutectic solvents—to extract these alkaloids. Among solvents tested, lactic acid, malic pyruvic acid exhibited highest extraction efficiencies. Optimal conditions for...

The key objective of this study was to determine the yield and chemical composition eight commercial samples one collected sample common vervain (Verbena officinalis L.) herb essential oil (EO) originating from seven different countries, subsequently, assess its potential for treating anxiety depression. According GC-MS analysis, 90 compounds were identified, 49 which discovered first time in V. EO. plants with highest content are Greece (4.7 mL/kg) South Carolina, USA (5.2 mL/kg). markers...

Background/Objectives. Flavonoids are a vast class of phenolic substances. To date, approximately 6000 plant-origin flavonoids have been discovered, and many them used in drug therapy. Therapeutic commonly formulated to conventional “one size fits all” dosage forms, such as tablets or hard cap-sules. However, the current trend pharmacy medicine is personalized therapy delivery systems (DDSs). Therefore, 3D printing an interesting technique for designing preparing novel pharmaceuticals...

According to the WHO data (2017), depression is most predominant disease worldwide, with about 300 million people suffering from it, and bipolar disorder second common. Therefore, it relevant research new medicines based on medicinal herbal raw materials anti-anxiety antidepressant effects. Common heather (Calluna vulgaris (L.) Hull.), a flowering plant of Ericaceae family, promising species for in this area. The aim study was investigate phytochemical profile several biological activities...

Growing blueberry (Vaccinium corymbosum L., Highbush blueberry) as a berry crop is developing dynamically, especially in warm temperate, subtropical, and tropical regions of the world. When cultivated on plantations, bushes are pruned annually, tons leaves become waste. Thus, aim present study was to create preparation from leaves, their chemical composition determine potential dietary supplement for prophylactic correction metabolic syndrome. Several schemes obtaining extracts have been...

The aim. Extracts of cranberry large leaves have prospects when used to correct insulin-resistant conditions. There­fore, create new drugs based on leaves, you need develop instructions for cultivating the plant, harvesting raw materials and methods quality control. Therefore, aim research was determine pa­rameters standardization (Oxycoccus macrocarpus (Ait.) Pursh) swamp cranberries palustris Pers.). Materials methods. Macro- microscopic studies were performed according method SPhU 2.8.23...

In pharmaceutics, 3D printing is considered as a promising future technology for fabricating more complex patient-specific drug delivery systems (DDSs). An anti-staphylococcal herbal preparation, "Chlorophyllipt", produced mainly in liquid form by the pharmaceutical industry Ukraine, and it composed of an ethanolic eucalypt extract (EE). Since staphylococcal infections have become true challenge health care all over world, would be relevant justified to develop aqueous gels present EE...

L., family Rubiaceae, is a widely spread species in the