A5058523505- Essential Oils and Antimicrobial Activity
- Natural product bioactivities and synthesis
- Phytochemistry and Biological Activities
- Phytochemical compounds biological activities
- Ionic liquids properties and applications
- Berberine and alkaloids research
- Ginger and Zingiberaceae research
- Alkaloids: synthesis and pharmacology
- Phytochemicals and Antioxidant Activities
- Plant-based Medicinal Research
- IoT-based Smart Home Systems
- Quantum Computing Algorithms and Architecture
- Obesity, Physical Activity, Diet
- Water Quality Monitoring Technologies
- Bioactive natural compounds
- Chromatography in Natural Products
- Traditional and Medicinal Uses of Annonaceae
- Adversarial Robustness in Machine Learning
- Synthesis of Indole Derivatives
- Quantum and electron transport phenomena
- Neurological Disease Mechanisms and Treatments
- Diet and metabolism studies
- Eating Disorders and Behaviors
- Natural Compound Pharmacology Studies
- Marine Sponges and Natural Products
Hue University
2019-2025
Ho Chi Minh City University of Technology
2020-2024
Vietnam National University Ho Chi Minh City
2019-2023
Cho Ray Hospital
2020
University of Missouri
2017-2018
A sustainable and comprehensive process for extracting triterpenoids from persimmon leaves was developed the first time. This method utilizes deep eutectic solvents extraction macroporous resins recovery of triterpenoids.
Rutin and flavonoids derived from Sophora japonica hold significant potential for various bioactivities. The objective of this study is to improve the ultrasonic-assisted extraction procedure obtaining rutin total japonica. Moreover, purification these ethanol extract was accomplished using macroporous resins. Under optimal conditions, efficiency were 32.49% 48.40%, respectively. Out 11 resins tested purification, results indicated that DAX-8 ADS-7 two most efficient meticulously optimized...
The present study aimed to determine the bioactivities of essential oils extracted from leaves Paramignya trimera and Limnocitrus littoralis, including cytotoxicity, antiviral, antibacterial, antimycotic, antitrichomonas effects. Herein, it was indicated that P. L. littoralis showed no cytotoxicity on normal cells, namely MT-4, BHK-21, MDBK, Vero-76. oil (i) exhibited strongest inhibition against Staphylococcus aureus with MIC MLC values 2% (v/v); (ii) 8% (v/v) in Candida parapsilosis; (iii)...
The rapid emergence of drug-resistant strains and novel viruses have motivated the search for new anti-infectious agents. In this study, chemical compositions cytotoxicity, as well antibacterial, antifungal, antitrichomonas, antiviral activities essential oils from leaves, rhizomes, whole plant Hornstedtia bella were investigated. GC/MS analysis showed that β-pinene, E-β-caryophyllene, α-humulene found at high concentrations in oils. exhibited (i) inhibition against Staphylococcus aureus,...
An efficient choline chloride-based DES method is used to extract curcumin in turmeric residue for the first time.
Objective This study focuses on evaluating the inhibitory activity of pongaglabrone and pongapin, isolated from Pongamia pinnata in our previous research, inhibit α-glucosidase, an enzyme involved carbohydrate metabolism. Inhibition α-glucosidase is a key target for controlling type 2 diabetes, making these compounds promising candidates further research. Methods In vitro assays were conducted to evaluate effects pongapin α-glucosidase. Computational approaches, including Density Functional...
Berberine, palmatine, and coptisine are bioactive alkaloids commonly found in medicinal plants, including Coptis chinensis Franch. (Ranunculaceae). To address the limitations of conventional volatile organic solvents, this study employed eco-friendly solvents—aqueous solutions surfactants, carboxylic acids, deep eutectic solvents—to extract these alkaloids. Among solvents tested, lactic acid, malic pyruvic acid exhibited highest extraction efficiencies. Optimal conditions for...
The present study aimed to determine the antimicrobial activity and chemical composition of leaves-extracted essential oil Leoheo domatiophorus Chaowasku, D.T. Ngo H.T. Le (L. domatiophorus), including antibacterial, antimycotic, antitrichomonas antiviral effects. was obtained using hydrodistillation, with an average yield 0.34 ± 0.01% (v/w, dry leaves). There were 52 constituents as identified by GC/MS available authentic standards, representing 96.74% entire leaves oil. comprised three...
The present study aimed to determine the chemical compositions and bioactivities of essential oil Atalantia sessiflora Guillaumin (A. sessiflora), including antibacterial, antimycotic, antitrichomonas, anti-inflammatory antiviral effects.The from leaves A. was extracted by hydrodistillation using a Clevenger apparatus. Chemical were identified GC/MS. Antimicrobial antitrichomonas activity determined microdilution method; MTT method.The average yield 0.46 ± 0.01% (v/w, dry leaves). A number...
We propose an active-space approximation to reduce the quantum resources required for variational eigensolver (VQE). Starting from double exponential unitary coupled-cluster ansatz and employing downfolding technique, we arrive at effective Hamiltonian active space composed of bare a correlated potential caused by internal-external interaction. The is obtained one-body second-order Møller-Plesset perturbation theory (OBMP2), which derived using canonical transformation cumulant...
This research aimed to identify the volatile compounds of essential oils found in rhizomes and leaves Zingiber monophyllum Gagnep. is first phytochemical investigation this species. Essential from Z. were obtained by hydrodistillation analyzed gas chromatography coupled with mass spectrometry (GC/MS). Twenty-three accounting for 90.9% rhizome identified, while there seventeen components corresponding 91.8% leaf oil. The major constituents β-pinene (44.9% 29.8%), borneol (5.2% 3.1%), α-pinene...
Aims In this study, five essential oils (EOs) from different species of Lavandula hybrida abrialis, for R.C., 'super A', Z' and vera its hybrids Lavender were evaluated against 26 dust-isolated fungal strains North Africa.
The essential oil from the leaves of Paramignya trimera (Oliv.) Guillaum was obtained by hydrodistillation and analysed Gas Chromatography-coupled with Mass Spectrometry (GC/MS) for first time. A total forty-three components were identified accounting 89.5 % oil. This dominated sesquiterpene hydrocarbons (39.6 %) oxygenated sesquiterpenes (41.7 %). major constituents P. determined as β-caryophyllene (10.5 %), oxide (9.9 7-epi-α-eudesmol (7.6 γ-muurolene (6.8
In the prevention of epidemic and pandemic emerging neglected viral infections, natural products are an important source lead compounds. Hornstedtia bella Škorničkis is a rhizomatous herb growing in forest central Vietnam. essential oil (Hb EO) was recently characterised by our group as endowed antimicrobial activity against Staphylococcus aureus Methicillin-Resistant strains. Here, we describe for first time evaluation Hb EO spectrum viruses responsible human diseases. resulted active...
Abstract A new flavanol derivative, (2 R ,3 )-3-acetoxy-7-hydroxy-3′,4′-methylenedioxyflavan ( 1 ), was co-isolated from the rhizomes of Zephyranthes ajax Hort. with following seven known compounds: 7-hydroxyflavan 2 7,4′-dihydroxyflavan 3 7,4′-dihydroxy-8-methylflavan 4 7,3′-dihydroxy-4′-methoxyflavan 5 5,4′-dihydroxy-7-methoxy-6-methylflavan 6 7-hydroxy-3′,4′-methylenedioxyflavanone 7 ) and haemanthamine 8 ). Their structures were elucidated by combining 1D-/2D-NMR, CD, UV HRESIMS data,...
This research aims to identify the volatile compounds from rhizomes and leaves of Newmania sontraensis. The constituents essential oil N. sontraensis were analyzed by Gas Chromatography-Mass Spectrometry (GC/MS). Thirty-one identified in compared which showed thirty-two corresponding 83.28 % 76.41 content, respectively. chemical composition rhizome was characterized hydrocarbon monoterpenes accounting for 36.26 %. major found included β-pinene (22.41%), 1,8-cineole (8.32 %),...
The present study provides the first information on chemical composition and acetylcholinesterase inhibitory activity of essential oil (EO) from leaves Mitrephora poilanei Weeras. & R.M.K.Saunders Vietnam. Gas chromatography gas chromatography-mass spectrometry analysis revealed that main components M. EO were β-caryophyllene (13.2%), α-humulene (10.5%), germacrene D (8.1%), β-elemene (5.2%) bicyclogermacrene (5.1%). anti-acetylcholinesterase assay showed displayed moderate with IC50 value...
The oil from the leaves of Limnocitrus littoralis (Miq.) Swingle was obtained by hydrodistillation and investigated gas chromatography combined with mass spectrometry (GC/MS), anti-inflammatory effect examined on a LPS-induced RAW264.7 cells. An aggregate forty components were identified, representing 93.0% oil. This subjugated monoterpene hydrocarbons (27.7%), sesquiterpene (32.3%) oxygenated sesquiterpenes (4.6%). significant constituents L. essential determined as follows; myrcene...
(1) Background: Plants possess many acyl-acyl carrier protein (acyl-ACP) thioesterases (TEs) with unique specificity. One such TE is methylketone synthase 2 (MKS2), an enzyme a single-hotdog-fold structure found in several tomato species that hydrolyzes 3-ketoacyl-ACPs to give free 3-ketoacids. (2) Methods: In this study, we identified and characterized MKS2 homolog gene, namely, GmMKS2, the genome of soybean (Glycine max). (3) Results: GmMKS2 underwent alternative splicing produce three...
Xanthine oxidase (XO) is a potential target for gout disease experiments on animals and humans. Using molecular docking technique to search anti-XO compounds from Vietnamese medicinal plants, we discovered that numerous Uvaria cordata (Dunal) Alston (Annonaceae family) showed this activity. Among these, cordauvarin A exhibited the strongest binding affinity (−8.8 kcal/mol) XO through interaction with 5 amino acids (eg Gln-1194, Ala-1079, Ser-1080, Met-1038, Arg-912) of protein. Lipinski's...