Khanh Huyen Thi Pham

ORCID: 0000-0003-3240-2699
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About
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Research Areas
  • Fungal Biology and Applications
  • Mycorrhizal Fungi and Plant Interactions
  • Lichen and fungal ecology
  • Phytochemicals and Antioxidant Activities
  • Ubiquitin and proteasome pathways
  • Bioactive Compounds and Antitumor Agents
  • Curcumin's Biomedical Applications
  • Chromatography in Natural Products
  • Polysaccharides and Plant Cell Walls
  • Phytochemistry and Biological Activities
  • Plant-derived Lignans Synthesis and Bioactivity
  • Genomics, phytochemicals, and oxidative stress
  • Autophagy in Disease and Therapy
  • Bioactive natural compounds
  • Histone Deacetylase Inhibitors Research
  • Enzyme-mediated dye degradation

Dongguk University
2024-2025

University of Da Nang
2023-2025

Ho Chi Minh City University of Science
2023

Objective This study focuses on evaluating the inhibitory activity of pongaglabrone and pongapin, isolated from Pongamia pinnata in our previous research, inhibit α-glucosidase, an enzyme involved carbohydrate metabolism. Inhibition α-glucosidase is a key target for controlling type 2 diabetes, making these compounds promising candidates further research. Methods In vitro assays were conducted to evaluate effects pongapin α-glucosidase. Computational approaches, including Density Functional...

10.1177/1934578x251321051 article EN cc-by-nc Natural Product Communications 2025-02-01

Ganoderma multipileum, a wood decay mushroom, was initially discovered and classified in Taiwan through the analysis of its morphology internal transcribed spacer (ITS) region nuclear ribosomal DNA. In this study, we identified mushroom associated with dieback Delonix regia (Boj. ex Hook.) Raf., woody ornamental street tree Vietnam, as multipileum. This classification based on phylogenetic ITS, RPB2, TEF1 sequences, well assessment scanning electron microscope observation basidiospores. The...

10.1177/00368504231195503 article EN cc-by-nc Science Progress 2023-07-01

Abstract Ganoderma multipileum was initially discovered in Taiwan as a wood decay fungus on many host plants. However, the detailed taxonomy of this genus has suffered from lack in-depth investigation. In study, classification these fungi described based their morphology, phylogeny three regions (ITS, RPB2, and TEF1 sequences), assessment scanning electron microscope photographs basidiospores. addition, similarities differences characteristics mushroom comparison to related species were...

10.21203/rs.3.rs-2421198/v1 preprint EN cc-by Research Square (Research Square) 2023-01-04

The polysaccharides found in Amauroderma subresinosum have been recognized, but their characterization has limited. In this study, enriched polysaccharide fractions (ASF) were extracted from the mycelia of using hot water, sodium hydroxide, and acetone. To determine these ASF structural characteristics, deproteination precipitation with cold ethanol performed to remove residual proteins. Fourier transform infrared (FTIR) spectroscopy was employed assess purity ASF, while gel permeation...

10.26538/tjnpr/v7i7.24 article EN cc-by-nc-nd Tropical Journal of Natural Product Research 2023-07-31

In the present study, bioactivity-guided extraction and isolation of n-hexane fraction fruits Vietnamese Schisandra sphenanthera led to five dibenzocyclooctadiene lignans as gomisin N (1), schisandrin C (2), H (3), D (4), (5). All isolates were tested for their inhibition NO production in LPS-induced RAW 264.7 cells. Among them, compounds 4 5 showed weak with ICSUB50/SUB values 25.0 ± 1.6 24.8 2.0 μM, respectively. Compound 1 exhibited an value 15.8 2.1 meanwhile, (2) most potent 8.5 0.5 μM....

10.20307/nps.2023.29.4.312 article EN Natural Product Sciences 2023-12-31
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