A5029223637- Voice and Speech Disorders
- Surgical Simulation and Training
- Tracheal and airway disorders
- Head and Neck Cancer Studies
- Ear Surgery and Otitis Media
- Head and Neck Surgical Oncology
- Lung Cancer Diagnosis and Treatment
- Hearing, Cochlea, Tinnitus, Genetics
- Respiratory and Cough-Related Research
- Vestibular and auditory disorders
- Hearing Loss and Rehabilitation
- Sinusitis and nasal conditions
- Dysphagia Assessment and Management
- Anatomy and Medical Technology
- Nasal Surgery and Airway Studies
- Pediatric health and respiratory diseases
- Digital Imaging in Medicine
- Obstructive Sleep Apnea Research
- Cleft Lip and Palate Research
- Allergic Rhinitis and Sensitization
- Soft Robotics and Applications
- Coenzyme Q10 studies and effects
- Infant Health and Development
- Meningioma and schwannoma management
- Body Composition Measurement Techniques
University of Genoa
2012-2025
Ospedale Policlinico San Martino
2020-2023
University of Brescia
2016
Diagnostic Sonar (United Kingdom)
2011
Viterbo University
1997
Università Cattolica del Sacro Cuore
1997
Objectives To assess a new application of artificial intelligence for real‐time detection laryngeal squamous cell carcinoma (LSCC) in both white light (WL) and narrow‐band imaging (NBI) videolaryngoscopies based on the You‐Only‐Look‐Once (YOLO) deep learning convolutional neural network (CNN). Study Design Experimental study with retrospective data. Methods Recorded videos LSCC were retrospectively collected from in‐office transnasal videoendoscopies intraoperative rigid endoscopies....
The high rate of positive margins after transoral laser microsurgery (TLM) remains a matter debate. This study investigates the effect intraoperative narrow band imaging (NBI) examination on incidence superficial surgical in early glottic cancer treated by TLM.Between January 2012 and October 2013, 82 patients affected Tis-T1a were with TLM type I or II cordectomies. Intraoperative NBI evaluation was performed using 0-degree 70-degree rigid telescopes. Surgical specimens oriented marking...
To introduce a novel computerized surgical system for improved usability, intuitiveness, accuracy, and controllability in robot-assisted laser phonomicrosurgery.Pilot technology assessment.The was developed involving newly designed motorized micromanipulator, touch-screen display, graphics stylus. The allows the control of CO2 through interaction between stylus live video area. This empowers with ability to have actual effect on site. Surgical enhancements afforded by this were established...
Narrow Band Imaging (NBI) is an endoscopic visualization technique useful for upper aero-digestive tract (UADT) cancer detection and margins evaluation. However, NBI analysis strongly operator-dependent requires high expertise, thus limiting its wider implementation. Recently, artificial intelligence (AI) has demonstrated potential applications in UADT videoendoscopy. Among AI methods, deep learning algorithms, especially convolutional neural networks (CNNs), are particularly suitable...
Background T3 laryngeal cancer encompasses heterogeneous lesions whose treatment is still debated. The purpose of this study was to evaluate transoral laser microsurgery (TLM) in management selected glottic and supraglottic cancers. Methods Fifty-six patients with squamous cell carcinomas (SCCs) treated by TLM ± selective neck dissection adjuvant therapy were evaluated terms overall survival (OS), disease-free (DFS), organ preservation rates. Results For the entire cohort, 5-year OS DFS...
Robotic telesurgery is a new concept in surgical care that has gained relevance over the past two decades. Now, with introduction of 5G mobile networks, this becoming practical. Here, we report surgeons successfully performed complex transoral laser microsurgeries on vocal cords an adult human cadaver located 15 km away from them. This was possible thanks to high bandwidth and ultra-low latency telecommunication system, which allowed for precise remote control robotic instruments full HD (...
The early detection of head and neck squamous cell carcinoma (HNSCC) is essential to improve patient prognosis enable organ function preservation treatments. objective this study assess the feasibility using electrical bioimpedance (EBI) sensing technology detect HNSCC tissue. A prospective was carried out analyzing tissue from 46 patients undergoing surgery for HNSCC. goal correct identification pathologic a novel needle-based EBI device AI-based classifiers. Considering data overall...
The efficacy mepolizumab in severe asthmatic patients is proven the literature. Primarily to study effect of on exacerbations, steroid dependence, and continuation long term. Secondarily evaluate drug nasal polyps. Analyzing data from SANI (Severe Asthma Network Italy) clinics, we observed treated with 100 mg/4 weeks, for a period 3 years. 157 were observed. Exacerbations reduced first year (−84.6%) progressively 90 95% second third ones. Steroid-dependent decreased 54% 21% subsequently 11%...
Robotics has a significant potential to enhance the overall capacity and efficiency of healthcare systems. Robots can help surgeons perform better quality operations, leading reductions in hospitalisation time patients impact surgery on their postoperative life. In particular, robotics have microsurgery, which presents stringent requirements for superhuman precision control surgical tools. Microsurgery is, fact, expected gain importance growing range specialties as novel technologies...
Letters1 December 2020Operating From a Distance: Robotic Vocal Cord 5G Telesurgery on CadaverAlperen Acemoglu, PhD, Giorgio Peretti, MD, Matteo Trimarchi, Juljana Hysenbelli, MS, Jan Krieglstein, Andre Geraldes, Nikhil Deshpande, Pierre Marie Vincent Ceysens, Darwin Gordon Caldwell, Marco Delsanto, Ottavia Barboni, MM, Tommaso Vio, Sabrina Baggioni, Alessandro Vinciguerra, Alberto Sanna, Elettra Oleari, Andrea Luigi Camillo Carobbio, Luca Guastini, Francesco Mora, and Leonardo S. Mattos,...
Objectives: This study presents SmartProbe, an electrical bioimpedance (EBI) sensing system based on a concentric needle electrode (CNE). The allows the use of commercial CNEs for accurate EBI measurement, and was specially developed in-vivo real-time cancer detection. Approach: Considering uncertainties in measurements due to CNE manufacturing tolerances, we propose calibration method statistical learning. is done by extracting correlation between measured impedance value |Z|, material...
The present study evaluated the safety and efficacy of dupilumab in severe uncontrolled type 2 chronic rhinosinusitis with nasal polyps (CRSwNP).A retrospective analysis was conducted on a cohort adult patients affected by CRSwNP treated dupilumab. Maxillofacial computed tomography, evaluation blood eosinophils serum IgE levels, measurement polyp score (NPS), smell identification test (SSIT-16), sinonasal outcome test-22 (SNOT-22) asthma control (ACT) were performed. Follow-up at weeks, 1,...
We investigated the prevalence and intensity of symptoms use drugs for symptom control among all HIV-infected patients reporting to outpatient clinics or wards 15 clinical centres in central Italy, recording epidemiological data on three consecutive days. A total 1128 were observed tabulated. Their most frequent asthenia (55%), anorexia (34%), cough (32%), pain (29%), fever (29%). Opioid analgesics used 3% these non-opioid 13%. large majority presented with regardless stage their disease....
Piezosurgery is an ultrasound instrument (24.7-29.5 kHz) capable of cutting bone without necrosis and nonmineralized tissue damage. The aim this work has been to determine the time required for a well-trained surgeon perform otological surgery with piezoelectric device.Case series planned data collection. Sixty-three patients affected by otosclerosis 63 chronic otitis media were enrolled. For each disease, divided into three numerically equal groups, group assigned surgeon. Patients...
The aim of this study was to evaluate the efficiency sulphurous thermal water in treatment chronic rhinosinusitis (CRS).Eighty patients with CRS were included and randomly assigned into two groups. Patients underwent a 12-day course warm vapour inhalations nasal irrigations group A, physiological solution B.Compared B, A results as follows: serum concentration IgE significantly lower (p<0.05) 12 days (76.27+26.3 mg/dl vs. 97.44±45.4) 3 months after beginning (75.48+26.1 98.37±41.4); IgA...
The aim of this study was to provide the anatomic rationale for a transnasal approach orbital apex and cavernous sinus, evaluate its applicability efficiency.One hundred patients with lesions apex, optic nerve, clivus, parapharyngeal space, infratemporal fossa, or pterygopalatine fossa were reviewed over 10-year period. All underwent an endoscopic sinus. surgical technique required standard sinus surgery set. possible complications recorded classified as intraoperative postoperative.There in...
Development of transnasal fiberoptic laryngoscopy, integration an operative channel (OC), the advent high-definition television imaging, with improvements in laser technology, cleared way for office-based laryngology. Three treatment categories can be identified: bioendoscopy-guided biopsy; laryngeal injection; laser-assisted surgery.26 patients underwent OBPs at Otolaryngology Clinic IRCCS Policlinico San Martino, Genoa, Italy. Sixty-eight procedures were performed: 60 recurrent respiratory...