A5017101507- Reconstructive Facial Surgery Techniques
- Infective Endocarditis Diagnosis and Management
- Platelet Disorders and Treatments
- Complement system in diseases
- Antimicrobial Resistance in Staphylococcus
- Streptococcal Infections and Treatments
- Reconstructive Surgery and Microvascular Techniques
- Blood Coagulation and Thrombosis Mechanisms
- Breast Implant and Reconstruction
Friedrich-Alexander-Universität Erlangen-Nürnberg
2019
Universitätsklinikum Erlangen
2019
Heidelberg University
2013-2015
University Hospital Heidelberg
2013-2015
University Medical Centre Mannheim
2013-2015
DKFZ-ZMBH Alliance
2013
German Cancer Research Center
2013
Universität Hamburg
2013
University Medical Center Hamburg-Eppendorf
2013
University Medical Center Groningen
2013
During pathogenesis of infective endocarditis, Staphylococcus aureus adherence often occurs without identifiable preexisting heart disease. However, molecular mechanisms mediating initial bacterial adhesion to morphologically intact endocardium are largely unknown.Perfusion activated human endothelial cells with fluorescent bacteria under high-shear-rate conditions revealed 95% attachment the S by ultralarge von Willebrand factor (ULVWF). Flow experiments VWF deletion mutants and heparin...