Steven Linfield

ORCID: 0000-0001-9911-307X
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About
Contact & Profiles
Research Areas
  • Electrochemical Analysis and Applications
  • Electrochemical sensors and biosensors
  • Minerals Flotation and Separation Techniques
  • Analytical Chemistry and Sensors
  • Alzheimer's disease research and treatments
  • Computational Drug Discovery Methods
  • Molecular Sensors and Ion Detection
  • NMR spectroscopy and applications
  • Electron and X-Ray Spectroscopy Techniques
  • Micro and Nano Robotics
  • Advanced biosensing and bioanalysis techniques
  • Advanced Chemical Sensor Technologies
  • Spectroscopy and Quantum Chemical Studies
  • Biosensors and Analytical Detection
  • Nanopore and Nanochannel Transport Studies
  • Electrical and Bioimpedance Tomography
  • Electronic and Structural Properties of Oxides
  • Molecular Junctions and Nanostructures
  • Electrowetting and Microfluidic Technologies
  • Conducting polymers and applications
  • Iron oxide chemistry and applications
  • Ultrasonics and Acoustic Wave Propagation
  • Advanced Thermodynamics and Statistical Mechanics
  • Ultrasound and Cavitation Phenomena
  • Microfluidic and Bio-sensing Technologies

Polish Academy of Sciences
2022-2024

Institute of Physical Chemistry
2022-2024

University of Southampton
2019-2020

Recently, shot noise has been shown to be an inherent part of all charge-transfer processes, leading a practical limit quantification 2100 electrons (≈0.34 fC) [ Curr. Opin. Electrochem. 2020, 22, 170-177]. Attainable limits are made much larger by greater background currents and insufficient instrumentation, which restricts progress in sensing single-entity applications. This limitation can overcome converting electrochemical charges into photons, detected with sensitivity, even down...

10.1021/acs.analchem.3c00694 article EN cc-by Analytical Chemistry 2023-07-17

Improving the sensitivity and ultimately range of particle sizes that can be detected with a single pore extends versatility Coulter counting technique. Here, to enable have greater sensitivity, we developed tested novel differential resistive pulse sensing (DiS) system for sizing particles. To do this, response was generated through time shift approach utilizing "self-servoing regime" final signal operate zero background in absence translocation. The detection characterization series...

10.1021/acssensors.9b01087 article EN ACS Sensors 2019-07-10

Nanobubbles are fascinating but controversial objects. Although there is strong evidence for the existence of surface bound nanobubbles, possibility stable nanobubbles in bulk remains question. In this work, we show how ultrasonication electrolytes can create transient nanobubbles. To do this, glass nanopores used as Coulter counters to detect During ultrasonication, these shown exist relatively high concentrations while bubble activity on a solid media close pore driven by ultrasound....

10.1021/acs.jpcc.0c00435 article EN The Journal of Physical Chemistry C 2020-03-19

The development of Alzheimer’s Disease (AD) has been linked to abnormal quantities β-amyloid peptides in the brain. majority studies have focussed on Aβ(1-40/42) amyloids and their Cu(II)-Aβ(1-40/42) complexes which are responsible for production reactive oxygen nitrogen species (ROS RNS), highly toxic neurons. According recent amyloid plaques, Aβ(4-42), is an N-truncated version Aβ(1-42), as prevalent Aβ(1-42) Although Cu(II) ions, bounded by can be oxidized Cu(III) its do not appear...

10.26434/chemrxiv-2023-8n92m preprint EN cc-by 2023-11-28

Bubble oscillation has many applications, from driving local fluid motion to cleaning. However, in order exploit their action, a full understanding of this motion, particularly confined spaces (such as crevices etc. which are important ultrasonic decontamination) is important. To end, here we show how Coulter counter can be used characterize microbubbles produced through the ultrasonication electrolytes. These shown exist relatively high concentrations while bubble activity driven by...

10.1039/c9cp05103a article EN Physical Chemistry Chemical Physics 2019-01-01

Recently, shot noise has been shown to be an inherent part of all charge transfer processes, leading a practical limit quantification 2100 electrons (~0.34 fC) (Curr. Opin. Electrochem. 2020, 22, 170177). Attainable limits are made much larger by greater background currents and insufficient instrumentation, which restricts progress in sensing single-entity applications. This limitation can overcome converting electrochemical charges into photons, detected with sensitivity, even down...

10.26434/chemrxiv-2023-trx9k preprint EN cc-by 2023-02-08

Steven Linfield opened a general discussion of the paper by Alain Walcarius: Pore diameter can be limiting factor during metal deposition in nanopores. Did you encounter any problems filling nanopores with aniline solution? What percentage pores did observe electropolymeris

10.1039/d2fd90002e article EN Faraday Discussions 2022-01-01

Electrochemistry has a limit of detection imposed by the inherent shot-noise present in electrical currents [1]. As result, direct measurement single-electron charge transfer processes is not feasible using electrochemical methods. However, luminescence can be measured with single photon resolution and development method to efficiently convert an signal optical one expected key step overcoming electrochemistry [2]. An conversion technique based on closed bipolar recently been demonstrated...

10.1149/ma2022-02542048mtgabs article EN Meeting abstracts/Meeting abstracts (Electrochemical Society. CD-ROM) 2022-10-09
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