A5061332129- Nanoplatforms for cancer theranostics
- Aerogels and thermal insulation
- Nanoparticle-Based Drug Delivery
- Nanoparticles: synthesis and applications
- Gold and Silver Nanoparticles Synthesis and Applications
- Photodynamic Therapy Research Studies
- Cancer Cells and Metastasis
- Electrospun Nanofibers in Biomedical Applications
- Photoacoustic and Ultrasonic Imaging
- Laser Applications in Dentistry and Medicine
- Wound Healing and Treatments
- Computational Drug Discovery Methods
- Advanced Cellulose Research Studies
- Spectroscopy Techniques in Biomedical and Chemical Research
- Bee Products Chemical Analysis
- Advanced Nanomaterials in Catalysis
- Dental materials and restorations
- Prostate Cancer Diagnosis and Treatment
- Skin Protection and Aging
- Nonmelanoma Skin Cancer Studies
- Ocular and Laser Science Research
- Bone Tissue Engineering Materials
- Cell Image Analysis Techniques
- Immunotherapy and Immune Responses
University of Lisbon
2020-2024
Scaffolds grafting combined with local delivery of antibiotics at the injury site may promote bone regeneration along prevention infections. In this work, a processing strategy combining 3D-printing polysaccharide-based inks supercritical (sc)CO2 technology was employed to manufacture drug-loaded, nanostructured, and personalized-to-patient aerogels for first time. Methylcellulose (MC) as graft matrix endowed nanohydroxyapatite (nHA) confer bioactivity required in tissue engineering (BTE)....
In recent years, gold nanoparticles (AuNPs) have aroused the interest of many researchers due to their unique physicochemical and optical properties. AuNPs are being explored in a variety biomedical fields, either diagnostics or therapy, particularly for localized thermal ablation cancer cells after light irradiation. Besides promising therapeutic potential AuNPs, safety constitutes highly important issue any medicine medical device. For this reason, present work, production characterization...
Prostate cancer (PCA) is the second most common diagnosis in men and fifth leading cause of death worldwide. The conventional treatments available are beneficial to only a few patients and, those, some present adverse side effects that eventually affect quality life patients. Thus, there an urgent need for effective, less invasive targeted specific PCA. Photothermal therapy (PTT) minimally provides localized effect tumour cell ablation by activating photothermal agents (PTA) mediate...
Breast cancer is a high-burden malignancy for society, whose impact boosts continuous search novel diagnostic and therapeutic tools. Among the recent approaches, photothermal therapy (PTT), which causes tumor cell death by hyperthermia after being irradiated with light source, represents high-potential strategy. Furthermore, effectiveness of PTT can be improved combining near infrared (NIR) irradiation gold nanoparticles (AuNPs) as enhancers. Herein, an alternative synthetic method using...
Abstract Nanostructured scaffolds based on cellulose with advanced performances and personalized morphologies for bone tissue engineering are under technological development. 3D-printing supercritical carbon dioxide (scCO 2 ) technologies innovative processing strategies that, when combined, allow the precise fabrication of highly porous aerogel scaffolds. Novel sterile cellulose-in-cellulose aerogels decorated superparamagnetic iron oxide nanoparticles (SPIONs) synthesized in this work by...
Breast cancer is one of the most common cancers worldwide, which makes it a very impactful malignancy in society. can be classified through different systems based on main tumor features and gene, protein, cell receptors expression, will determine advisable therapeutic course expected outcomes. Multiple options have already been proposed implemented for breast treatment. Nonetheless, their use efficacy still greatly depend classification, treatments are commonly associated with invasiveness,...
The global impact of cancer emphasizes the importance developing innovative, effective and minimally invasive therapies. In context superficial cancers, development a multifunctional nanoparticle-based system its in vitro vivo safety efficacy characterization are, herein, proposed as proof-of-concept. This consists gold nanoparticles coated with hyaluronic oleic acids, functionalized epidermal growth factor for greater specificity towards cutaneous melanoma cells. nanoparticle is activated...
Aerogels are materials with unique properties, among which low density and thermal conductivity. They also known for their exquisite biocompatibility biodegradability. All these features make them attractive biomedical applications, such as potential use in photothermal therapy (PTT). This technique is, yet, still associated undesirable effects on surrounding tissues emphasizes the need to minimize exposure of healthy regions. One way do so relies able block radiation heat generated. might...
Presently, skin burns are considered one of the main public health problems and lack therapeutic options. In recent years, silver nanoparticles (AgNPs) have been widely studied, playing an increasingly important role in wound healing due to their antibacterial activity. This work is focused on production characterization AgNPs loaded a Pluronic® F127 hydrogel, as well assessing its antimicrobial wound-healing potential. has extensively explored for applications mainly appealing properties....
The properties of gold-based materials have been explored for centuries in several research fields, including medicine. Multiple published production methods gold nanoparticles (AuNPs) shown that the physicochemical and optical AuNPs depend on method used. These different AuNP allowed exploration their usefulness countless distinct biomedical applications over last few years. Here we present an extensive overview most commonly used methods, resulting potential application these diagnostic...
Breast cancer is one of the most frequently diagnosed malignancies and common causes death in women. Recent studies suggest that environmental exposures to certain chemicals, such as 7,12-Dimethylbenzanthracene (DMBA), a chemical present tobacco, may increase risk developing breast later life. The first-line treatments for (surgery, chemotherapy or combination both) are generally invasive associated with severe side effects high comorbidity. Consequently, novel approaches strongly required...