A5075055780- Viral Infections and Vectors
- Mosquito-borne diseases and control
- Malaria Research and Control
- Colorectal Cancer Treatments and Studies
- Genetic factors in colorectal cancer
- Model Reduction and Neural Networks
- Fluid Dynamics and Turbulent Flows
- Viral Infections and Outbreaks Research
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Colorectal Cancer Screening and Detection
- Chemokine receptors and signaling
- Aerodynamics and Acoustics in Jet Flows
- Computational Fluid Dynamics and Aerodynamics
- Cancer Immunotherapy and Biomarkers
- Atherosclerosis and Cardiovascular Diseases
University of Puerto Rico System
2020-2024
Texas State Technical College Harlingen
2016
Austin Health & Human Services Department
2016
Texas Department of State Health Services
2016
Centers for Disease Control and Prevention
2016
University of Puerto Rico, Medical Sciences Campus
2015
The Ohio State University
2007-2009
Development, experimental implementation, and the results of reduced-order model based feedback control subsonic shallow cavity flows are presented discussed. Particle image velocimetry (PIV) data proper orthogonal decomposition (POD) technique used to extract most energetic flow features or POD eigenmodes. The Galerkin projection Navier–Stokes equations onto these modes is derive a set nonlinear ordinary differential equations, which govern time evolution eigenmodes, for controller design....
Zika virus is a flavivirus transmitted primarily by Aedes species mosquitoes, and symptoms of infection can include rash, fever, arthralgia, conjunctivitis (1).* during pregnancy cause microcephaly other severe brain defects (2). Infection has also been associated with Guillain-Barré syndrome (3). In December 2015, Puerto Rico became the first U.S. jurisdiction to report local transmission virus, index patient reporting symptom onset on November 23, 2015 (4). This provides an update...
During a dengue epidemic in northern Mexico, enhanced surveillance identified 53 laboratory-positive cases southern Texas; 26 (49%) patients acquired the infection locally, and 29 (55%) were hospitalized. Of 83 patient specimens that initially IgM negative according to ELISA performed at commercial laboratory, 14 (17%) virus positive by real-time reverse transcription PCR Centers for Disease Control Prevention. Dengue types 1 3 identified, molecular phylogenetic analysis demonstrated close...
Background Chikungunya virus (CHIKV) is transmitted by Aedes species mosquitoes and the cause of an acute febrile illness characterized potentially debilitating arthralgia. After emerging in Caribbean late 2013, first locally-acquired case reported to public health authorities Puerto Rico occurred May 2014. During June–August 2014, household-based cluster investigations were conducted identify factors associated with infection, development disease, reporting. Methodology/Principal Findings...
West Nile virus (WNV) is a neurotropic arbovirus that was first isolated in 1937 the District of Uganda. The emerged New York 1999 and now endemic North America (2007). isolates from Puerto Rico were obtained 2007 chicken (PR20wh) mosquito pool (PR423). Our study further characterized these viral using vitro plaque morphology assays vivo Balb/c mice pathogenesis model. In experiments, PR WNV produced significantly smaller plaques Vero cells compared to strain (NY99). For propagated mammalian...
Abstract Background: Colorectal Cancer (CRC) has become the second leading cause of death related to cancer worldwide and third most common malignancy. CRC tumors are classified into stages describe cancer; early (stages I II) advanced III IV). Despite available screening methods scientific efforts in development a universal biomarker panel for detection, there still exists gap reliable non-invasive method Hispanic community. We aimed elucidate important pathways along with differential gene...
Background: Colorectal cancer (CRC) is a leading cause of death worldwide. Despite its preventability through screening, compliance still needs to improve due the invasiveness current tools. There growing demand for validated molecular biomarker panels minimally invasive blood-based CRC screening. This study assessed diagnostic accuracy four promising biomarkers, individually and in combination. Methods: case–control involved plasma samples from 124 cases age- sex-matched controls....
Dengue is an important arboviral disease with about 100 million dengue cases per year, of which, ~5% result in severe disease. Clinical differentiation from other acute febrile illnesses (AFI) difficult, and diagnostic blood tests are costly. We evaluated the utility anti-DENV IgM urine to identify among AFI patients enrolled a clinical study.Between May 2012-March 2013, 1538 study participants fever for ≤7 days were enrolled, medical history was obtained, serum specimens collected. Serum...
Abstract Despite evidence suggesting that current Colorectal Cancer (CRC) screening strategies reduce mortality rates, compliance is suboptimal; for this, our study aimed to evaluate the discriminatory potential of plasma cytokine and chemokine levels CRC detection in samples a Hispanic subpopulation. Using retrospective case-control design, we evaluated 20 cases age-gender matched controls from Puerto Rico Familial Registry (PURIFICAR). BD CBA Human Th1/Th2/Th17 Cytokine Chemokine kits were...