A5045313264- Spine and Intervertebral Disc Pathology
- Musculoskeletal pain and rehabilitation
- Anesthesia and Pain Management
- Spinal Fractures and Fixation Techniques
- Medical Imaging and Analysis
- Myofascial pain diagnosis and treatment
- Scoliosis diagnosis and treatment
- Pain Management and Placebo Effect
- Infectious Diseases and Tuberculosis
- Cervical and Thoracic Myelopathy
- Fibromyalgia and Chronic Fatigue Syndrome Research
- Traumatic Brain Injury Research
- Orthopedic Infections and Treatments
- Shoulder Injury and Treatment
- Occupational Health and Performance
- Clinical practice guidelines implementation
- Cardiac, Anesthesia and Surgical Outcomes
- Meta-analysis and systematic reviews
- Health Systems, Economic Evaluations, Quality of Life
- Pharmaceutical industry and healthcare
- Automotive and Human Injury Biomechanics
- Pelvic and Acetabular Injuries
- Pregnancy-related medical research
- Orthopaedic implants and arthroplasty
- Medical Practices and Rehabilitation
Stanford University
2012-2024
University Hospital and Clinics
2008-2023
Reed Medical (United Kingdom)
2021-2022
Orthofix (United States)
2022
Amazon (Germany)
2022
University of Pittsburgh
2022
Partners In Care
2022
University of Utah
2021
Stanford Medicine
1993-2017
Cornell University
2017
In Brief Study Design. Clinical practice guideline. Objective. To develop evidence-based recommendations on use of interventional diagnostic tests and therapies, surgeries, interdisciplinary rehabilitation for low back pain any duration, with or without leg pain. Summary Background Data. Management patients persistent disabling remains a clinical challenge. A number therapies surgery are available their is increasing, but in some cases utility uncertain controversial. Interdisciplinary has...
The surgical treatment of sciatica with discectomy is ineffective in a sizable percentage patients, and reherniation occurs after 5% to 15% such procedures. purpose the present study was determine if competence disc anulus type herniation could be used predict postoperative clinical outcomes following lumbar discectomy.A prospective observational 187 consecutive patients undergoing single-level primary conducted. A single surgeon performed all procedures, an independent examiner evaluated...
I retrospectively reviewed the records of 111 patients who had pyogenic vertebral osteomyelitis unrelated to an open procedure on spine. The mean age at time diagnosis was sixty years (range, eighteen eighty-four years); sixty-one (55 per cent) were old or more. Forty-four (40 impaired immune system secondary diabetes mellitus, use corticosteroids, chemotherapy for cancer, rheumatic immunological disease, renal hepatic failure, malnutrition, myelodysplasia. Magnetic resonance imaging,...
Prospective, match-cohort study of disc degeneration progression over 10 years with and without baseline discography. Objectives. To compare common degenerative findings between lumbar discs injected earlier those same levels in matched subjects not exposed to Summary Background Data. Experimental puncture animal vivo studies have demonstrated accelerated degeneration. Whether intradiscal diagnostic or treatment procedures used clinical practice causes any damage the punctured time is...
Background: Recombinant human bone morphogenetic protein-2 (rhBMP-2) is a growth factor known to have in vitro effects on the and invasiveness of cancer. It has been approved by U.S. Food Drug Administration limited doses for single-level anterior spinal arthrodesis, but it commonly used off-label at high doses. The effect rhBMP-2 risk cancer concern. We sought evaluate new cancers patients receiving high-dose rhBMP-2. Methods: publicly available data from pivotal, multicenter, randomized...
Experimental disc injections in subjects with no history of low back symptoms.To determine an experimental setting the relative pain response and pain-related behavior selected without a undergoing lumbar discography. This study aimed to select population that more closely represented patients discography clinical practice.Previous work has shown young, healthy men little degenerative disease problems, discographic usually did not cause significant pain. group differed from who undergo...
In Brief Study Design. This is a prospective study of the validity positive test result in provocative lumbar discography for diagnosis "discogenic pain." Objective. To investigate hypothesis that by strict criteria accurately identifies low back pain illness due to primary disc lesion. Summary and Background Data. According Sackett Haynes establishing diagnostic validity, no without gold standard external can be meaningfully applied. Provocative as determining pain" has, date, not been...
Prospective observational study with historical control. The prospective population consisted of 30 patients undergoing a posterior lumbar subtotal discectomy for disc herniation. This group was compared to cohort 46 treated limited alone.To compare clinical outcomes after versus herniations.Large anular defects found at have been associated more frequent reherniation when (i.e., removing only extruded or loose intervertebral fragments). A trial aggressive (subtotal) undertaken determine if...
Experimental disc injections in subjects with no history of low back symptoms.To determine an experimental model the reliability patients' subjective interpretation pain concordancy during provocative injection.Discography evaluation relies on a patient's assessment magnitude and quality injection. Reproduction significant injection, which is similar to usual pain, believed prove that injected source pain. In current study, this hypothesis was tested controlled setting patients known...