Sophie Leijdesdorff

ORCID: 0000-0001-9930-3391
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About
Contact & Profiles
Research Areas
  • Adolescent and Pediatric Healthcare
  • Child and Adolescent Psychosocial and Emotional Development
  • Family Support in Illness
  • Sex work and related issues
  • Health disparities and outcomes
  • Dementia and Cognitive Impairment Research
  • Health, psychology, and well-being
  • Mental Health and Patient Involvement
  • Child Abuse and Trauma
  • Youth Substance Use and School Attendance
  • Child and Adolescent Health
  • Maternal Mental Health During Pregnancy and Postpartum
  • Family Caregiving in Mental Illness
  • Global Public Health Policies and Epidemiology
  • Frailty in Older Adults
  • Nutrition and Health in Aging
  • Amyotrophic Lateral Sclerosis Research
  • Physical Activity and Health
  • Neural and Behavioral Psychology Studies
  • Mental Health Research Topics
  • Mental Health Treatment and Access
  • Health, Environment, Cognitive Aging
  • HIV, Drug Use, Sexual Risk
  • Cerebrovascular and genetic disorders
  • Schizophrenia research and treatment

Bohn Stafleu van Loghum (Netherlands)
2024

Maastricht University
2017-2024

Erasmus MC
2016-2017

Abstract Introduction Detecting functional decline from normal aging to dementia is relevant for diagnostic and prognostic purposes. Therefore, the Amsterdam IADL Questionnaire (A‐IADL‐Q) was developed: a 70‐item proxy‐based tool with good psychometric properties. We aimed design short version while preserving its quality. Methods Study partners of subjects ( n = 1355), ranging cognitively subjects, completed original A‐IADL‐Q. selected items using stepwise procedure combining missing data,...

10.1016/j.dadm.2017.03.002 article EN cc-by-nc-nd Alzheimer s & Dementia Diagnosis Assessment & Disease Monitoring 2017-01-01

Introduction: Substance use disorder patients show impairments in working memory (WM) functioning. Previous findings indicate that a WM training results improvements of capacity (WMC) and decreased clinical symptoms range mental disorders, including alcohol disorder. Method: The aim the current study is to investigate efficacy 24-session addition treatment as usual on craving, WMC, substance use, impulsivity, attention bias, psychopathology using randomized double-blind placebo-controlled...

10.1080/13803395.2017.1372367 article EN Journal of Clinical and Experimental Neuropsychology 2017-09-21

Abstract Aim Although mental disorders often emerge early in life, only a minority of young people receive timely and appropriate health care. A worldwide youth movement aims to prevent development persistence psychiatric disorders. As part this movement, the first four @ease centres were opened Netherlands. is driven, professionally supported initiative, providing peer‐to‐peer counselling, anonymous free charge, for aged 12–25. Methods Data consist detailed description working method @ease,...

10.1111/eip.13294 article EN cc-by-nc-nd Early Intervention in Psychiatry 2022-03-27

Abstract Introduction Trials to test disease-modifying treatments for frontotemporal dementia are eagerly awaited and sensitive instruments assess potential treatment effects increasingly urgent, yet lacking thus far. We aimed identify gene-specific assessing clinical onset disease progression by comparing cognitive functioning between bvFTD patients across genetic mutations. Methods examined differences in 7 domains with GRN ( n = 20), MAPT 29) or C9orf72 31) mutations, non-carriers 24),...

10.1007/s00415-020-09738-y article EN cc-by Journal of Neurology 2020-02-12

Purpose The mismatch between the number of young people that require mental health care and who actually receive it, questions access to care. This study aims gain in-depth understanding barriers facilitators in pathway among 12 25 year olds as experienced by visitors youth walk-in centres Dutch @ease Foundation.Methods Open interviews were conducted explore participants' experiences attitudes towards Following inductive thematic analysis, pathways described.Results Fifteen participants...

10.1080/17482631.2021.1963110 article EN cc-by-nc International Journal of Qualitative Studies on Health and Well-Being 2021-01-01

Little is known about the burden of (sub-threshold) mental health problems in youth.To examine terms health-related quality life (HRQoL) and cost-of-illness, for first visitors Dutch youth walk-in centres (@ease).A bottom-up, prevalence-based disease study from a societal perspective. HRQoL was assessed through EuroQoL (EQ-5D-5L), cost-of-illness via items truancy care utilization.Participants (N = 80) showed decreased compared to general population youth. In three months prior their 1st...

10.1080/09638237.2020.1836555 article EN cc-by-nc-nd Journal of Mental Health 2020-10-22

Innovative youth mental health services around the globe vigorously work on increasing highly needed care accessibility but their service users and effectiveness have rarely been studied. The Dutch walk-in centres of @ease opened in 2018, with currently 11 locations at which free anonymous peer-to-peer counselling is offered to young people aged 12-25. aim this protocol outline to-be-conducted research @ease.Three studies are outlined: (1) an outcome evaluation visits using hierarchical...

10.1111/eip.13443 article EN cc-by-nc-nd Early Intervention in Psychiatry 2023-06-07

Abstract Aim Young people around the age of 18 receiving mental health care usually face transition from child and adolescent (CAMHS) to adult services (AMHS) bringing risk disruption in continuity care. Recognizing importance early intervention this vulnerable life‐period, study aims emphasize a client‐centred approach for group. For deeper understanding specific needs group, working method Dutch youth (YMH) team secondary setting is described, including some clinical characteristics...

10.1111/eip.12887 article EN cc-by-nc-nd Early Intervention in Psychiatry 2019-11-03

Abstract Background: Worldwide, the division between Child and Adolescent Mental Health Services (CAMHS) Adult (AMHS) has frequently resulted in fragmented care with an unprepared, non-gradual transition. To improve continuity of other service transition experiences, user input is essential. However, such previous qualitative studies are from a decade ago or focused on one mental disorder country. The aim present study was to learn users’ experiences suggested improvements. Methods:...

10.1017/ipm.2024.5 article EN cc-by-nc-nd Irish Journal of Psychological Medicine 2024-04-02

Highly accessible youth initiatives worldwide aim to prevent worsening of mental health problems, but research into outcomes over time is scarce.

10.1192/bjo.2024.58 article EN cc-by-nc-nd BJPsych Open 2024-05-01

Children of parents with a mental disorder and/or addiction (COPMI) are at increased risk developing disorder. In spite preventive interventions that can decrease the problem development, COPMI not automatically offered help. 2013, mandatory check was implemented in Netherlands, requiring every health care professional to whether their adult patients have children and assess these children's safety needs. Earlier research has shown gap between regulations actual integration clinical practice...

10.3389/fpsyt.2022.807251 article EN cc-by Frontiers in Psychiatry 2022-03-18

10.1007/s12454-024-1804-6 article NL Kind & Adolescent Praktijk 2024-03-01

Background: Sexually exploited young men are prevalent, yet underrepresented in clinical practice, policy and research. There multiple barriers that often prevent to disclose seek or receive support, such as gender norms, limited awareness of victimization feelings guilt shame. Objective: By gaining more insight into the background characteristics who experienced sexual exploitation their needs, this study aims raise better inform policymakers, care- educational professionals on adequate...

10.1016/j.chiabu.2024.106794 article EN cc-by Child Abuse & Neglect 2024-04-17

Introduction Sexual exploitation is a human rights violation that has detrimental impact on the psychological-, physical- and social well-being of victims. Sexually exploited male youth are prevalent, yet underrepresented in clinical practice, policy research. There multiple barriers often prevent to disclose seek or receive support, such as gender norms, limited awareness victimization feelings guilt shame. Objectives By gaining more insight into background characteristics victims their...

10.1192/j.eurpsy.2024.536 article EN cc-by-nc-nd European Psychiatry 2024-04-01

Purpose This study aims to explore how young people in child and adolescent mental health services (CAMHS) the UK, Ireland, The Netherlands Croatia, experienced leaving CAMHS identified a range of factors impeding optimal discharge or transition adult (AMHS). Design/methodology/approach Interviews about planning, including what information was provided their ongoing needs, undertaken with 34 aged 17–24, all previous current attendees CAMHS. Some interviews included accounts by parents...

10.1108/mhrj-10-2022-0066 article EN Mental Health Review Journal 2023-08-26

Early detection and intervention of mental health problems in youth are topical given that disorders often start early life. Young people with emerging however, present non-specific, fluctuating symptoms. Recent reports indicate a decline social functioning (SF) as an sign specific such depression or anxiety, making SF favorable transdiagnostic approach for earlier intervention. Our aim was to investigate the value relation symptoms, predictor psychopathology over time, while exploring...

10.1016/j.comppsych.2022.152309 article EN cc-by-nc-nd Comprehensive Psychiatry 2022-03-15

Detecting functional decline from healthy aging to dementia is relevant for diagnostic purposes, early treatments and prevention studies. To this end, we developed the Amsterdam IADL Questionnaire (A-IADL-Q). The A-IADL-Q a 70-item informant-based tool have previously shown it good psychometric properties. improve its conciseness reduce respondent burden, aimed develop short version whilst preserving A total of 1326 informants subjects, ranging cognitively subjects patients with dementia,...

10.1016/j.jalz.2016.06.987 article EN Alzheimer s & Dementia 2016-07-01

Frontotemporal dementia (FTD) is the second most common type of at an early age. In last two decades three genetic mutations causing FTD have been discovered: MAPT, GRN and C9orf72 repeat expansion, covering familial cases FTD. Comparing neuropsychological profiles in carriers would enable a better differentiation, even distinguishing between different underlying causes. The aim current study to provide with or C9orf72mutation. Neuropsychological data patients diagnosed carrying either MAPT...

10.1016/j.jalz.2016.06.1981 article EN Alzheimer s & Dementia 2016-07-01
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