A5086284450- Schizophrenia research and treatment
- Mental Health and Psychiatry
- Mental Health Research Topics
- Mental Health Treatment and Access
- Child and Adolescent Psychosocial and Emotional Development
- Bipolar Disorder and Treatment
- Treatment of Major Depression
- Health disparities and outcomes
- Psychosomatic Disorders and Their Treatments
- Adolescent and Pediatric Healthcare
- Psychiatric care and mental health services
- Obsessive-Compulsive Spectrum Disorders
- Family Support in Illness
- Health, psychology, and well-being
- Personality Disorders and Psychopathology
- Dutch Social and Cultural Studies
- Autism Spectrum Disorder Research
- Maternal Mental Health During Pregnancy and Postpartum
- Health Systems, Economic Evaluations, Quality of Life
- AI in Service Interactions
- Mental Health and Patient Involvement
- Family Caregiving in Mental Illness
- Cannabis and Cannabinoid Research
- Psychological Treatments and Disorders
- Health and Medical Studies
War Child
2021-2024
De Bascule
2016-2021
University Medical Center Utrecht
2016
GGZ Rivierduinen
2010-2014
Amsterdam UMC Location University of Amsterdam
2009-2012
University of Amsterdam
2011
GGZ Friesland
2010
In order to bring about implementation of routine screening for psychosis risk, a brief version the Prodromal Questionnaire (PQ; Loewy et al., 2005) was developed and tested in general help-seeking population. We assessed consecutive patient sample 3533 young adults who were nonpsychotic disorders at secondary mental health services Hague with PQ. performed logistic regression analyses CHi-squared Automatic Interaction Detector decision tree analysis shorten original 92 items. Receiver...
: Evidence for the effectiveness of treatments subjects at ultrahigh risk (UHR) developing psychosis remains inconclusive.Objective: A new cognitive behavioral intervention specifically targeted biases (ie, Cognitive Behavioral Therapy [CBT] UHR patients plus treatment as usual [TAU] called CBTuhr) is compared with TAU in a group young help-seeking subjects.Methods: total 201 were recruited 4 sites and randomized. In most cases, CBTuhr was an add-on therapy because people seeking help...
Rietdijk J, Klaassen R, Ising H, Dragt S, Nieman DH, van de Kamp Cuijpers P, Linszen D, der Gaag M. Detection of people at risk developing a first psychosis: comparison two recruitment strategies. Objective: Better strategies are needed to improve the identification ultra‐high psychosis. This study explores effectiveness strategies: screening method in consecutive help‐seeking population entering secondary mental health services for non‐psychotic problems vs. referred diagnostic center an...
Previously, we demonstrated that cognitive behavior therapy for ultra-high risk (called CBTuhr) halved the incidence of psychosis over an 18-month period. Follow-up data from same study are used to evaluate longer-term effects at 4 years post-baseline. The Dutch Early Detection and Intervention Evaluation was a randomized controlled trial 196 UHR patients comparing CBTuhr with treatment-as-usual (TAU) comorbid disorders TAU only. Of original patients, 113 consented 4-year follow-up (57.7%; =...
Psychotic disorders are a serious mental health problem. Intervention before the onset of psychosis might result in delaying onset, reducing impact or even preventing first episode psychosis. This study explores effectiveness cognitive behavioural therapy (CBT) targeting biases that involved formation delusions persons with an ultra-high risk for developing A single blind randomised controlled trial compares CBT treatment as usual All help seeking patients aged 14 to 35 years referred...
Background Although there is evidence for the effectiveness of interventions psychosis among ultra-high-risk (UHR) groups, health economic evaluations are lacking. This study aimed to determine cost and cost–utility cognitive–behavioural therapy (CBT) prevent first-episode psychosis. Method The Dutch Early Detection Intervention Evaluation was a randomized controlled trial 196 UHR patients with an 18-month follow-up. All participants were treated routine care (RC) non-psychotic disorders....
This study aims to evaluate the long-term cost-effectiveness of add-on cognitive behavior therapy (CBT) for prevention psychosis individuals at ultrahigh risk (UHR) psychosis. The Dutch Early Detection and Intervention randomized controlled trial was used, comparing routine care (RC; n = 101) with plus CBT UHR (here called CBTuhr; 95). A analysis conducted treatment response (defined as proportion averted transitions psychosis) an outcome a cost-utility quality-adjusted life years (QALYs)...
Velthorst E, Nieman DH, Klaassen RMC, Becker HE, Dingemans PM, Linszen de Haan L. Three year course of clinical symptomatology in young people at ultra high risk for transition to psychosis. Objective: The investigation into the (UHR) those patients who eventually do not meet psychosis-threshold criteria within 3-year timeframe study. Method: UHR symptoms, GAF score and employment status was investigated 57 did make a psychosis were examined Dutch Prediction Psychosis Study Amsterdam,...
Abstract Aim Although mental disorders often emerge early in life, only a minority of young people receive timely and appropriate health care. A worldwide youth movement aims to prevent development persistence psychiatric disorders. As part this movement, the first four @ease centres were opened Netherlands. is driven, professionally supported initiative, providing peer‐to‐peer counselling, anonymous free charge, for aged 12–25. Methods Data consist detailed description working method @ease,...
Purpose The mismatch between the number of young people that require mental health care and who actually receive it, questions access to care. This study aims gain in-depth understanding barriers facilitators in pathway among 12 25 year olds as experienced by visitors youth walk-in centres Dutch @ease Foundation.Methods Open interviews were conducted explore participants' experiences attitudes towards Following inductive thematic analysis, pathways described.Results Fifteen participants...
Little is known about the burden of (sub-threshold) mental health problems in youth.To examine terms health-related quality life (HRQoL) and cost-of-illness, for first visitors Dutch youth walk-in centres (@ease).A bottom-up, prevalence-based disease study from a societal perspective. HRQoL was assessed through EuroQoL (EQ-5D-5L), cost-of-illness via items truancy care utilization.Participants (N = 80) showed decreased compared to general population youth. In three months prior their 1st...
Background Ethnicity has been associated with different incidence rates and symptom profiles in young patients psychotic-like disorders. No studies so far have examined the effect of ethnicity on symptoms people an At Risk Mental State (ARMS). Method In this cross-sectional study, we analysed relationship between baseline data severity psychopathology scores 201 help-seeking who met ARMS criteria agreed to participate Dutch Early Detection Intervention (EDIE-NL) trial. Eighty-seven these had...
<i>Background:</i> This study examines the ability of Scale Prodromal Symptoms (SOPS) to differentiate between negative and depression symptoms in a young help-seeking ultrahigh risk (UHR) group. <i>Methods:</i> SOPS data 77 patients at UHR for psychosis were analyzed with an exploratory factor analysis. The extracted Depression was validated Beck Inventory (BDI). Negative subscale Positive Syndrome (PANSS). <i>Results:</i> Four factors from SOPS:...
Self-report instruments for the assessment of depressive symptoms in patients with psychotic disorders are scarce. The Quick Inventory Depressive Symptoms (QIDS-SR16) may be a useful self-report instrument, but has received little attention this field. This paper aimed to test psychometric properties QIDS-SR16 questionnaire disorder.Patients diagnosed disorder from health care institutions Netherlands were included study. assessed and Calgary Depression Scale Schizophrenia (CDSS). Psychotic...
Background Depression is a clinically relevant dimension, associated with both positive and negative symptoms, in patients schizophrenia. However, siblings it unknown whether depression subclinical symptoms. Method Depressive symptoms their association were examined 813 healthy of non-affective psychotic disorder, 822 527 controls. episodes meeting DSM-IV-TR criteria (lifetime) depressed mood assessed the Comprehensive Assessment Symptoms History (CASH) all three groups. In patient group,...
Background Current ultra-high-risk (UHR) criteria appear insufficient to predict imminent onset of first-episode psychosis, as a meta-analysis showed that about 20% patients have psychotic outcome after 2 years. Therefore, we aimed develop stage-dependent predictive model in UHR individuals who were seeking help for co-morbid disorders. Method Baseline data on symptomatology, and environmental psychological factors 185 (aged 14–35 years) participating the Dutch Early Detection Intervention...
Highly accessible youth initiatives worldwide aim to prevent worsening of mental health problems, but research into outcomes over time is scarce.
Computerized adaptive tests (CATs) for positive and negative psychotic experiences were developed tested in N = 5705 help-seeking, non-psychotic young individuals. Instead of presenting all items, CATs choose a varying number different items during test administration depending on respondents' previous answers, reducing the average while still obtaining accurate person estimates. We assessed appropriateness two-parameter logistic models to symptoms Prodromal Questionnaire (PQ), computed...