A5073274674- Dementia and Cognitive Impairment Research
- Functional Brain Connectivity Studies
- Autism Spectrum Disorder Research
- Alzheimer's disease research and treatments
- Advanced Neuroimaging Techniques and Applications
- Bipolar Disorder and Treatment
- Cannabis and Cannabinoid Research
- Neurological disorders and treatments
- Blood Pressure and Hypertension Studies
- Parkinson's Disease Mechanisms and Treatments
Amsterdam UMC Location Vrije Universiteit Amsterdam
2017-2020
Amsterdam University Medical Centers
2018
Amsterdam Neuroscience
2018
Amsterdam UMC Location University of Amsterdam
2016
We aimed to describe the Subjective Cognitive Impairment Cohort (SCIENCe) study design, cross-sectionally participant characteristics, and evaluate SCD-plus criteria. The SCIENCe is a prospective cohort of subjective cognitive decline (SCD) patients. Participants undergo extensive assessment, including cerebrospinal fluid collection optional amyloid positron emission tomography scan, with annual follow-up. primary outcome measure clinical progression. Cross-sectional evaluation first 151...
Abstract Objectives Grey matter network disruptions in Alzheimer's disease (AD) are associated with worse cognitive impairment cross‐sectionally. Our aim was to investigate whether indications of a more random organization longitudinal decline specific functions individuals subjective (SCD). Experimental design : We included 231 SCD who had annually repeated neuropsychological assessment (3 ± 1 years; n = 646 investigations) available from the Amsterdam Dementia Cohort (54% male, age: 63 9,...
Article Abstract Objective: To investigate which neuropsychological tests can discriminate between behavioral variant frontotemporal dementia (bvFTD) and psychiatric disorders presenting with similar late-onset frontal changes, such as apathy, disinhibition, reduced empathy, or compulsive behavior. Methods: Patients changes in middle late adulthood received extensive baseline examinations, including assessment brain imaging. After 2 years, examinations were repeated patients diagnosed...