A5081949568- Schizophrenia research and treatment
- Mental Health and Psychiatry
- Mental Health Research Topics
- Mental Health Treatment and Access
- Bipolar Disorder and Treatment
- Psychosomatic Disorders and Their Treatments
- Health Systems, Economic Evaluations, Quality of Life
- Psychiatric care and mental health services
- Autoimmune Bullous Skin Diseases
- Renal Diseases and Glomerulopathies
- Cannabis and Cannabinoid Research
- Child and Adolescent Psychosocial and Emotional Development
- Treatment of Major Depression
- Vasculitis and related conditions
- Posttraumatic Stress Disorder Research
- Healthcare Decision-Making and Restraints
- Sleep and Work-Related Fatigue
- Psychological Well-being and Life Satisfaction
- Autism Spectrum Disorder Research
- Magnesium in Health and Disease
- Healthcare Systems and Public Health
- Tryptophan and brain disorders
- Psychotherapy Techniques and Applications
- Psychopathy, Forensic Psychiatry, Sexual Offending
- Child Abuse and Trauma
GGZ Rivierduinen
2023-2024
Parnassia Groep
2012-2021
Amsterdam Public Health
2010-2012
German Environment Agency
1997
Environment Agency Austria
1997
Katharinenhospital
1980-1981
Freie Universität Berlin
1972
In order to bring about implementation of routine screening for psychosis risk, a brief version the Prodromal Questionnaire (PQ; Loewy et al., 2005) was developed and tested in general help-seeking population. We assessed consecutive patient sample 3533 young adults who were nonpsychotic disorders at secondary mental health services Hague with PQ. performed logistic regression analyses CHi-squared Automatic Interaction Detector decision tree analysis shorten original 92 items. Receiver...
: Evidence for the effectiveness of treatments subjects at ultrahigh risk (UHR) developing psychosis remains inconclusive.Objective: A new cognitive behavioral intervention specifically targeted biases (ie, Cognitive Behavioral Therapy [CBT] UHR patients plus treatment as usual [TAU] called CBTuhr) is compared with TAU in a group young help-seeking subjects.Methods: total 201 were recruited 4 sites and randomized. In most cases, CBTuhr was an add-on therapy because people seeking help...
Rietdijk J, Klaassen R, Ising H, Dragt S, Nieman DH, van de Kamp Cuijpers P, Linszen D, der Gaag M. Detection of people at risk developing a first psychosis: comparison two recruitment strategies. Objective: Better strategies are needed to improve the identification ultra‐high psychosis. This study explores effectiveness strategies: screening method in consecutive help‐seeking population entering secondary mental health services for non‐psychotic problems vs. referred diagnostic center an...
Background Evidence was found for the effectiveness of virtual reality-based cognitive behavioral therapy (VR-CBT) treating paranoia in psychosis, but health-economic evaluations are lacking. Objective This study aimed to determine short-term cost-effectiveness VR-CBT. Methods The evaluation embedded a randomized controlled trial evaluating VR-CBT 116 patients with psychotic disorder suffering from paranoid ideation. control group (n=58) received treatment as usual (TAU) disorders accordance...
Previously, we demonstrated that cognitive behavior therapy for ultra-high risk (called CBTuhr) halved the incidence of psychosis over an 18-month period. Follow-up data from same study are used to evaluate longer-term effects at 4 years post-baseline. The Dutch Early Detection and Intervention Evaluation was a randomized controlled trial 196 UHR patients comparing CBTuhr with treatment-as-usual (TAU) comorbid disorders TAU only. Of original patients, 113 consented 4-year follow-up (57.7%; =...
Psychotic disorders are a serious mental health problem. Intervention before the onset of psychosis might result in delaying onset, reducing impact or even preventing first episode psychosis. This study explores effectiveness cognitive behavioural therapy (CBT) targeting biases that involved formation delusions persons with an ultra-high risk for developing A single blind randomised controlled trial compares CBT treatment as usual All help seeking patients aged 14 to 35 years referred...
Background Although there is evidence for the effectiveness of interventions psychosis among ultra-high-risk (UHR) groups, health economic evaluations are lacking. This study aimed to determine cost and cost–utility cognitive–behavioural therapy (CBT) prevent first-episode psychosis. Method The Dutch Early Detection Intervention Evaluation was a randomized controlled trial 196 UHR patients with an 18-month follow-up. All participants were treated routine care (RC) non-psychotic disorders....
This study aims to evaluate the long-term cost-effectiveness of add-on cognitive behavior therapy (CBT) for prevention psychosis individuals at ultrahigh risk (UHR) psychosis. The Dutch Early Detection and Intervention randomized controlled trial was used, comparing routine care (RC; n = 101) with plus CBT UHR (here called CBTuhr; 95). A analysis conducted treatment response (defined as proportion averted transitions psychosis) an outcome a cost-utility quality-adjusted life years (QALYs)...
The present study investigated the distribution of HLA‐antigens and Bf alleles in a group 21 patients suffering from biopsy proven Idiopathic Membranous Nephropathy (IMN). A statistically significant increase HLA‐DR3 (76.2%) was detected patient as well an MT‐2 (86%), which is new supertypic specificity defined within 8th International Histocompatibility Workshop 1980. No association between BfF1 IMN can be deduced this study. Only common (BfFF, BfFS, BfSS) were found presented here. Also...
Background Ethnicity has been associated with different incidence rates and symptom profiles in young patients psychotic-like disorders. No studies so far have examined the effect of ethnicity on symptoms people an At Risk Mental State (ARMS). Method In this cross-sectional study, we analysed relationship between baseline data severity psychopathology scores 201 help-seeking who met ARMS criteria agreed to participate Dutch Early Detection Intervention (EDIE-NL) trial. Eighty-seven these had...
BackgroundDespite robust empirical support for the efficacy of trauma-focused treatments, dissemination proves difficult, especially in relation to patients with comorbid psychosis. Many therapists endorse negative beliefs about credibility, burden, and harm such treatment.ObjectiveThis feasibility study explores impact specialized training on therapists' treatment within a randomized controlled trial.MethodTherapist-rated (n=16) expected expectancies were assessed at baseline,...
Background Current ultra-high-risk (UHR) criteria appear insufficient to predict imminent onset of first-episode psychosis, as a meta-analysis showed that about 20% patients have psychotic outcome after 2 years. Therefore, we aimed develop stage-dependent predictive model in UHR individuals who were seeking help for co-morbid disorders. Method Baseline data on symptomatology, and environmental psychological factors 185 (aged 14–35 years) participating the Dutch Early Detection Intervention...
Background This study aims to report on the design of a model determine cost-effectiveness prevention and treatment early psychosis (PsyMod) estimate ten-year budget impact interventions targeting individuals with ultra-high risk (UHR) developing or first episode (FEP).Methods PsyMod was built in parallel development new standard care for Netherlands. is state-transition cohort simulation considers six health states, namely (UHR), FEP, post-FEP, no-UHR, recovery/remission, death. Results are...
Abstract Purpose For many individuals with a psychotic disorder societal recovery is not accomplished. Research on trajectories mostly focussed patients first episode psychosis. The present study aims to identify distinct in those long duration of illness, through the identification patient subgroups that are characterized by homogeneous trajectories. Methods Longitudinal data were used from an ongoing dynamic cohort which people receive yearly measurements perform latent class growth...
Computerized adaptive tests (CATs) for positive and negative psychotic experiences were developed tested in N = 5705 help-seeking, non-psychotic young individuals. Instead of presenting all items, CATs choose a varying number different items during test administration depending on respondents' previous answers, reducing the average while still obtaining accurate person estimates. We assessed appropriateness two-parameter logistic models to symptoms Prodromal Questionnaire (PQ), computed...