A5001619297- Health Systems, Economic Evaluations, Quality of Life
- Healthcare Policy and Management
- Chronic Disease Management Strategies
- Global Health Care Issues
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Smoking Behavior and Cessation
- School Health and Nursing Education
- Health Promotion and Cardiovascular Prevention
- Pharmaceutical Economics and Policy
- Diabetes Management and Research
- Healthcare cost, quality, practices
- Diabetes Treatment and Management
- Diabetes Management and Education
- Climate Change Policy and Economics
- Health disparities and outcomes
- Dutch Social and Cultural Studies
- Global Public Health Policies and Epidemiology
- Schizophrenia research and treatment
- Global Cancer Incidence and Screening
- Primary Care and Health Outcomes
- Mental Health Treatment and Access
- Diabetes, Cardiovascular Risks, and Lipoproteins
- Obesity, Physical Activity, Diet
- Colorectal Cancer Screening and Detection
- Health Policy Implementation Science
National Institute for Public Health and the Environment
2016-2025
University of Groningen
2016-2025
University Medical Center Groningen
2014-2023
University Medical Center Utrecht
2012-2020
Utrecht University
2020
Health Forecasting
2005-2020
Netherlands Institute for Health Services Research
2020
Dialyse Centrum Groningen
2020
Medicines Evaluation Unit
2007-2017
Linköping University
2015
A trade-off exists between building confidence in health-economic (HE) decision models and the use of scarce resources. We aimed to create a practical tool providing model users with structured view into validation status HE models, address this trade-off.A Delphi panel was organized, completed by workshop during an international conference. The proposed constructed iteratively based on comments from, discussion amongst, panellists. During process, were solicited importance feasibility...
Obesity is a major cause of morbidity and mortality associated with high medical expenditures. It has been suggested that obesity prevention could result in cost savings. The objective this study was to estimate the annual lifetime costs attributable obesity, compare those similar smoking, discuss implications for prevention.
Chronic obstructive pulmonary disease (COPD) causes extensive disability, primarily among the elderly. On World Health Organization ranking list of disability-adjusted life years (DALYs), COPD rises from twelfth to fifth place 1990 2020. The purpose this study is single out impact changes in demography and smoking behavior on morbidity, mortality, health care costs. A dynamic multistate table model was used compute projections for Netherlands. Changes size composition population cause...
To contribute to evidence-based policy making, a dynamic Dutch population model of chronic obstructive pulmonary disease (COPD) progression was developed. The projects incidence, prevalence, mortality, and costs diagnosed COPD by the Global Initiative for Chronic Obstructive Lung Disease-severity stage 2000–2025, taking into account dynamics changes in smoking prevalence over time. It estimated that all patients 2000, 27% had mild, 55% moderate, 15% severe 3% very COPD. severity distribution...
To support health policy makers in setting priorities, quantifying the potential effects of tobacco control on burden disease is useful. However, smoking related to a variety diseases and dynamic cessation incidence these differ. Furthermore, many people who quit relapse, most them within relatively short period.In this paper, method presented for calculating interventions that allows deal with relapse effect time since quitting. A simulation model described links 14 diseases. demonstrate...
Abstract We aimed to estimate the prevalence, healthcare costs and number of deaths among people with chronic obstructive pulmonary disease (COPD) in England Scotland 2011–2030. adapted Dutch COPD Model by using English Scottish demographic, incidence, smoking prevalence mortality data make projections. In England, was estimated be 1.79% (95% uncertainty interval 1.77–1.81) 2011, increasing 2.19% (1.85–2.33) 2030. Scotland, 2.03% (1.96–2.10) 2011 2.20% (1.98–2.40) These increases were driven...
Component-based projections are commonly used to predict future growth in healthcare spending. The current study aimed compare pure component-based using microlevel data investigate their added value. microdata was find disease-specific time trends the number of patients that use hospital care and annual per patient spending (APHS). Total expenditure were then based on APHS disease category combined with demographic projections. As comparator, we a composite term derived from total trends....
To date, complete and long-term registrations of diseases events are not available in every situation. As a useful proxy, medication usage data is very promising. For instance, real-world dispensing from pharmacies attractive because the high validity drug data, large sample sizes, registration. However, before application as must be assessed. Therefore, this study, we aim to assess various medicines used proxy for major adverse cardio-cerebrovascular (MACCE), that is, identify an incident...
An important subject of debate in cost-utility analysis health care programmes is whether to include costs unrelated medical life years gained. The inclusion such likely be consequence the case primary prevention. This paper presents different strategies regarding not only costs, but also effects economic evaluations. Four ratios are presented and related criterion internal consistency. In addition, possibility relate a well-posed decision problem analysed. example computes for smoking...
OBJECTIVE To explore the potential long-term health and economic consequences of lifestyle interventions for diabetic patients. RESEARCH DESIGN AND METHODS A literature search was performed to identify patients in which issues were addressed. We selected recent (2003-2008), randomized controlled trials with a minimum follow-up 12 months. The outcomes these interventions, if implemented Dutch population, simulated computer-based model. Costs effects discounted at, respectively, 4 1.5%...
The inclusion of medical costs in life years gained economic evaluations health care technologies has long been controversial. Arguments favour the such are gaining support, which shifts question from whether to how include these costs. This paper elaborates on issue cost effectiveness analysis given current practice related diseases included. We combine insights theoretical literature unrelated with so-called 'red herring' literature. It is argued that for most interventions it would be...
Transparency in health economic decision modelling is important for engendering confidence the models and reliability of model-based cost-effectiveness analyses. The Mount Hood Diabetes Challenge Network has taken a lead promoting transparency through validation with biennial conferences which diabetes groups meet to compare simulated outcomes pre-specified scenarios often based on results pivotal clinical trials. Model registration potential method transparency, while also reducing...