A5101772928- Obesity, Physical Activity, Diet
- Health Systems, Economic Evaluations, Quality of Life
- Obesity and Health Practices
- Chronic Disease Management Strategies
- Nutritional Studies and Diet
- Eating Disorders and Behaviors
- Global Public Health Policies and Epidemiology
- Mobile Health and mHealth Applications
- Diet and metabolism studies
- Pregnancy and preeclampsia studies
- Diabetes Management and Research
- Digital Mental Health Interventions
- Behavioral Health and Interventions
- Diabetes, Cardiovascular Risks, and Lipoproteins
- Health disparities and outcomes
- Child Nutrition and Feeding Issues
- Health Policy Implementation Science
- Liver Disease Diagnosis and Treatment
- Nutrition and Health in Aging
- Cardiovascular Health and Risk Factors
- Birth, Development, and Health
- Primary Care and Health Outcomes
- Food Security and Health in Diverse Populations
- Healthcare cost, quality, practices
- Agriculture Sustainability and Environmental Impact
University of Sheffield
2016-2025
University of North Carolina at Chapel Hill
2023
University of Iceland
2023
Institute of Health Economics
2023
University of Southern Denmark
2023
University of Bath
2023
Monash University
2023
MRC Epidemiology Unit
2023
University of Cambridge
2023
Health economic decision-analytic models are used to estimate the expected net benefits of competing decision options. The true values input parameters such rarely known with certainty, and it is often useful quantify value maker reducing uncertainty through collecting new data. In context a particular problem, proposed research design can be quantified by its sample information (EVSI). EVSI commonly estimated via 2-level Monte Carlo procedure in which plausible data sets generated an outer...
Abstract Background Policies aimed at restricting the marketing of high fat, salt and sugar products have been proposed as one way improving population diet reducing obesity. In 2019, Transport for London implemented advertising restrictions on products. A controlled interrupted time-series analysis comparing with a north England control, suggested that had resulted in reduction household energy purchases. The aim study presented here was to estimate health benefits, cost savings equity...
Abstract Aims/hypothesis UK standard care for type 2 diabetes is structured education, with no effects on HbA 1c , small, short-term weight and low uptake. We evaluated whether remotely delivered tailored education combined commercial behavioural management cost-effective compared current in helping people to lower their blood glucose, lose weight, achieve remission improve cardiovascular risk factors. Methods conducted a pragmatic, randomised, parallel two-group trial. Participants were...
ABSTRACT Background Most weight lost during weight‐loss programmes is eventually regained. Interventions based on Acceptance and Commitment Therapy (ACT) demonstrate good evidence for long‐term loss, but are often costly difficult to scale up. Guided self‐help delivered using technology non‐specialist coaches could increase scalability, it unclear whether delivering ACT‐based interventions in this way feasible acceptable. Methods In feasibility study, 61 people who recently completed a...
Background Large out-of-home (OOH) food businesses in England have been required by law to display calorie information on menus since 6th April 2022. This study investigates whether the implementation of this policy was associated with changes calories purchased OOH. Methods Controlled interrupted time series analysis used estimate from all OOH outlets (intervention group). Secondary outcomes included purchases large chain outlets, non-chain and five sub-types (meals, lower-calorie coffee,...
To develop a cost-effectiveness model to compare Type 2 diabetes prevention programmes targeting different at-risk population subgroups with lifestyle intervention of varying intensity.An individual patient simulation was constructed simulate the development in representative sample adults without from UK population. The incorporates trajectories for HbA1c , 2-h glucose, fasting plasma BMI, systolic blood pressure, total cholesterol and HDL cholesterol. Patients can be diagnosed diabetes,...
Abstract Aim To analyse the cost‐effectiveness of different interventions for Type 2 diabetes prevention within a common framework. Methods A micro‐simulation model was developed to evaluate range including: (1) soft drinks taxation; (2) retail policy in socially deprived areas; (3) workplace intervention; (4) community‐based and (5) screening intensive lifestyle intervention individuals with high risk. Within model, follow metabolic trajectories (for BMI , cholesterol, systolic blood...
To evaluate potential return on investment of the National Health Service Diabetes Prevention Programme (NHS DPP) in England and estimate which population subgroups are likely to benefit most terms cost-effectiveness, cost-savings health benefits.Economic analysis using School for Public Research Model.England 2015-2016.Adults aged ≥16 with high risk type 2 diabetes (HbA1c 6%-6.4%). Population defined by age, sex, ethnicity, socioeconomic deprivation, baseline body mass index, HbA1c working...
Novel epidemiology models are required to link correlated variables over time, especially haemoglobin A1c (HbA1c) and body mass index (BMI) for diabetes prevention policy analysis. This article develops an model correlate metabolic risk factor trajectories. BMI, fasting plasma glucose, 2-h HbA1c, systolic blood pressure, total cholesterol high density lipoprotein (HDL) were analysed 16 years from 8150 participants of the Whitehall II prospective cohort study. Latent growth curve modelling...
The long-term impact and cost-effectiveness of weight management programs depend on posttreatment maintenance. There is growing evidence that interventions based third-wave cognitive behavioral therapy, particularly acceptance commitment therapy (ACT), could improve management; however, these are typically delivered face-to-face by psychologists, which limits the scalability types intervention.The aim this study to use an evidence-, theory-, person-based approach develop ACT-based...
It is challenging to predict long-term outcomes of interventions without understanding how they work. Health economic models public health often do not incorporate the many determinants individual and population behaviours that influence long term effectiveness. The aim this paper draw on psychology, sociology, behavioural economics, complexity science economics to: (a) develop a toolbox methods for incorporating influences behaviour into (PHEM-B); (b) set out research agenda modellers...
We aimed to evaluate the impact of a local sugar sweetened beverages (SSB) health promotion and 20p price increase in leisure centre venues estimate on consumption.Monthly cold drinks sales data attendance at centres across city Sheffield were analysed over period January 2015-July 2017. Interrupted time-series methods employed changes consumption per SSB non-SSB following introduction policy from August 2016 adjusting for seasonal variation autocorrelation. elasticities estimated with fixed...
Objectives To estimate the cost savings and health benefits of improving detection individuals at high risk cardiovascular disease (CVD) in England, to determine which patient subgroups these arise, compare different strategies for subsequent management. Design An economic analysis using School Public Health Research CVD Prevention Model. Setting England 2018. Participants Adults aged 16 older with one or more conditions, including hypertension, diabetes, non-diabetic hyperglycaemia, atrial...
Economic evaluations of lifestyle interventions, which aim to prevent diabetes/cardiovascular disease (CVD), have not included dementia. Lifestyle interventions decrease dementia risk and extend life expectancy, leading competing effects on health care costs. We demonstrate the feasibility including in a public cost-effectiveness analysis quantify overall impacts accounting for these effects.The School Public Health Research (SPHR) diabetes prevention model describes individuals' type 2...