- Health Systems, Economic Evaluations, Quality of Life
- Diabetes Treatment and Management
- Diabetes Management and Research
- Statistical Methods in Clinical Trials
- Acute Myocardial Infarction Research
- Spondyloarthritis Studies and Treatments
- Antiplatelet Therapy and Cardiovascular Diseases
- Autoimmune and Inflammatory Disorders Research
- Pharmaceutical Economics and Policy
- Coronary Interventions and Diagnostics
- Heart Failure Treatment and Management
- Pulmonary Hypertension Research and Treatments
- Lipoproteins and Cardiovascular Health
- Colorectal Cancer Treatments and Studies
- Biosimilars and Bioanalytical Methods
- Diabetes, Cardiovascular Risks, and Lipoproteins
- Psoriasis: Treatment and Pathogenesis
- Healthcare Technology and Patient Monitoring
- Multiple Sclerosis Research Studies
- Meta-analysis and systematic reviews
- Cancer Genomics and Diagnostics
- Diet and metabolism studies
- Atrial Fibrillation Management and Outcomes
- Animal Ecology and Behavior Studies
- Healthcare Policy and Management
ESiOR Oy (Finland)
2012-2025
Swedish Institute for Health Economics
2009-2019
University of Eastern Finland
2010-2012
Finland University
2012
University of York
2006-2007
University of St Andrews
2006-2007
The Centre for Health (New Zealand)
2007
Predators can have profound impacts on the dynamics of their prey that depend how predator consumption is affected by density (the predator's functional response). Consumption a generalist expected to densities all its major species (its multispecies response, or MSFR), but most studies generalists focussed response only one species.Using Bayesian methods, we fit an MSFR field data from avian hen harrier Circus cyaneus) feeding three different species. We use simple graphical approach show...
Abstract Treatment patterns of pulmonary arterial hypertension (PAH) and chronic thromboembolic (CTEPH) in Finland are unknown. Guidelines now recommend early escalation treatment for PAH. We evaluated how well Finnish practice follows guidelines, initiations outcomes related. The patients cohort includes all PAH CTEPH diagnosed between 2008 2020 university hospitals. Drug therapy was analysed with medical/procedural history available, changes the 4‐tier comparative, prospective registry...
Background. Trastuzumab is a standard treatment of HER2-positive early breast cancer in many countries, and it usually given as one year adjuvant treatment. However, its cost-effectiveness has not been assessed Finland. The Finland Herceptin (FinHer) trial compared shorter 9-week protocol against no trastuzumab with promising results. aim this study was to assess the potential based on recently published five-year follow-up results FinHer trial. Methods. An evaluation model constructed using...
Objective:This study constructed the Economic and Health Outcomes Model for type 2 diabetes mellitus (ECHO-T2DM), a long-term stochastic microsimulation model, to predict costs health outcomes in patients with T2DM. Naturally, usefulness of model depends upon its predictive accuracy. The objective this work is present results formal validation exercise ECHO-T2DM.Methods:The validity ECHO-T2DM was assessed using criteria recommended by International Society Pharmacoeconomics Research/Society...
<h3>Objective</h3> To estimate the cost-effectiveness of primary angioplasty compared with thrombolysis for acute ST elevation myocardial infarction. <h3>Design</h3> Cost analysis UK observational database, incorporated into decision analytical model. <h3>Methods</h3> Patients receiving treatment within a comprehensive service were control patients thrombolysis-based care. The costs and delays to estimated. These estimates then an existing model that synthesises evidence from 22 randomised...
The aim of this health economic analysis was to compare the cost-effectiveness ticagrelor versus clopidogrel within German care system. A two-part decision model adapted treatment with or in a low-dose acetylsalicylic acid (ASA) cohort (≤150 mg) for all ACS patients and subtypes NSTEMI/IA STEMI. decision-tree approach chosen first year after initial hospitalization based on trial observations from subgroup PLATO study. Subsequent years were estimated by Markov model. Following macro-costing...
Objective To assess the frequency of warfarin use, achieved international normalised ratio (INR) balance among users and primary healthcare outpatient costs patients with atrial fibrillation (AF). Design Retrospective, non-interventional registry study. Setting Primary healthcare. Participants All AF (n=2746) treated in one Finnish health centre between October 2010 March 2012. Methods Data on resource individually defined target INR range test results were collected from database for...
Direct oral anticoagulant (DOAC) use for the prevention of thromboembolic complications in patients with non-valvular atrial fibrillation (AF) has increased steadily Finland. DOACs have been shown to be cost-effective comparison warfarin, but published evidence relative cost-effectiveness between is still scarce and mostly based on indirect comparisons clinical trial evidence. The aim this study was compare apixaban dabigatran, rivaroxaban warfarin a Finnish setting using real-life where...
Atopic dermatitis (AD) affects health and quality of life it has great impact on both health-care costs to the society.The objective this study was develop a model analyse cost-effectiveness barrier-strengthening moisturizing cream as maintenance therapy compared with no treatment after initial betamethasone valerate in adult patients AD Sweden. A further aim apply similar health-economic analysis for Denmark, Norway Finland.A Markov simulation developed including data from three sources:...
Objectives . Quantify changes in hospital resource use Finland following initiation of risperidone long-acting injection (RLAI). Materials and Methods A retrospective multi-center chart review (naturalistic setting) was used to compare annual bed-days episodes for 177 schizophrenia patients (mean age 47.1 years, 52% female, 72% hospitalized) before after RLAI (between January 2004 June 2005) using the within-patient “mirror-image” study design. The base case analytical approach allocated...