Guillermo Grazioli

ORCID: 0000-0001-9969-3780
Publications
Citations
Views
---
Saved
---
About
Contact & Profiles
Research Areas
  • Dental materials and restorations
  • Dental Research and COVID-19
  • Endodontics and Root Canal Treatments
  • Dental Implant Techniques and Outcomes
  • Dental Erosion and Treatment
  • Mesenchymal stem cell research
  • Dental Trauma and Treatments
  • Cannabis and Cannabinoid Research
  • Occupational Health and Safety in Workplaces
  • Pediatric health and respiratory diseases
  • Scientific and Engineering Research Topics
  • Orthodontics and Dentofacial Orthopedics
  • COVID-19 and Mental Health
  • Photopolymerization techniques and applications
  • Tissue Engineering and Regenerative Medicine
  • Collagen: Extraction and Characterization
  • Health and Medical Education
  • Building materials and conservation
  • Medical research and treatments
  • Periodontal Regeneration and Treatments
  • Infant Health and Development
  • Dental Anxiety and Anesthesia Techniques
  • Dental Radiography and Imaging
  • Electrospun Nanofibers in Biomedical Applications
  • Silk-based biomaterials and applications

Universidad de la República
2017-2024

Universidad La República
2021

ORCID
2020-2021

Universidade Federal de Pelotas
2016-2020

Universidad de Montevideo
2017-2020

Univates
2019

Abstract In this study, poly (lactic-co-glycolic acid) (PLGA) microparticles loaded with cannabidiol (CBD) were synthesized (PLGA@CBD microparticles) and embedded up to 10 wt% in a chondroitin sulfate/polyvinyl alcohol hydrogel matrix. vitro chemical, physical, biological assays carried out validate the potential use of modified hydrogels as biomaterials. The had spherical morphology narrow range size distribution. CBD encapsulation efficiency was around 52%, loading approximately 50%....

10.1007/s10856-023-06773-9 article EN cc-by Journal of Materials Science Materials in Medicine 2024-02-14

Objective: In this study, a comparative evaluation of the physicochemical properties Cention N and other direct restorative materials was performed. Three materials—a resin-modified glass ionomer (Fuji II LC), an alkasite-based resinous material (Cention N), resin composite (Tetric Ceram)—were characterized in terms degree conversion, Knoop hardness number (KHN) ratio, flexural strength, elastic modulus, water sorption, solubility, microshear bond strength to dentin, immediate microleakage,...

10.1590/1678-7757-2023-0219 article EN cc-by Journal of Applied Oral Science 2024-01-01

The aim of this study was to evaluate the influence three low-cost additional thermal treatments, available in dental office, on mechanical, chemical and optical properties a light-cured resin composite indicated for direct restorations but used as indirect restorative. TPH3 (Dentsply) light-polymerized using light-emitting diode curing unit submitted experimental treatments: dry heat at 170 °C 5 min, autoclave 121 6 or microwave oven 450 W 3 min. without any treatment negative control...

10.1590/0103-6440201902473 article EN cc-by Brazilian Dental Journal 2019-06-01

Abstract The aim of presented systematic scoping review was to investigate the actual and future clinical possibilities regenerative therapies their ability regenerate bone, periodontal pulp with histological confirmation nature formed tissue. Electronic search conducted using a combination between Keywords MeSH terms in PubMed, Scopus, ISI-Web Science Cochrane library databases up January 2016. Two reviewers independently papers judgment. Screened studies were read following predetermined...

10.1590/0103-6440201902053 article EN cc-by Brazilian Dental Journal 2019-03-01

The COVID-19 pandemic has significantly influenced the routine of healthcare workers. This study investigated impact on dental practice and dentists' feelings in Latin America.A survey was conducted with dentists from 11 Spanish-speaking American countries September-December 2020. Professionals were invited by email via an open campaign promoted social media. questions care routines, changes, about pandemic. Descriptive statistics used to identify frequencies distributions variables....

10.1186/s12913-022-07792-y article EN cc-by BMC Health Services Research 2022-03-25

The objective of this study was to evaluate the effect radiant exposure on chemical and physical properties four commercial dental resin composites. composites used were Kalore, Admira, Tetric N-Ceram Bulk Fill, Filtek Z350 XT. subjected three curing protocols: 1000 mW/cm² for 5 s, 10 400 25 s. flexural strength, elastic modulus, water sorption, solubility, degree conversion, polymerization shrinkage evaluated. results analyzed by means ANOVA Tukey tests. For Admira significant differences...

10.3390/dj6040055 article EN cc-by Dentistry Journal 2018-10-07

The objective of this work was to evaluate the effect different protocols on shear bond strength (SBS) repairs made aged composite resin substrates. Eighty cylindrical specimens (IPS Empress Direct, Ivoclar-Vivadent) were prepared, and divided into two main groups: in group 1 a silane agent applied, while 2, not applied. Each then subdivided four groups according adhesive system used: control, without any adhesive, Single Bond Universal, Tetric Clearfil SE Bond. As reference group, cohesive...

10.1080/01694243.2022.2052414 article EN Journal of Adhesion Science and Technology 2022-03-16

The objective of the present study was to evaluate effect irradiance and radiant exposure on chemical-mechanical properties a resin composite. A micro-hybrid composite (Clearfil AP-X, Kuraray) investigated under two different irradiances: low (300 mW/cm2) high (800 exposures: 8 16 J/cm2. Four groups, named Low J/cm2, High J/cm2 were tested, their flexural strengths, elastic moduli, depths cure, degrees conversion evaluated. Data analyzed using two-way ANOVA Tukey's test. multiple linear...

10.1590/1807-3107bor-2022.vol36.0082 article EN cc-by Brazilian Oral Research 2022-01-01

Abstract Although the biological properties of mesenchymal stem cells (MSC) are well-characterized in vitro, MSC clinical application is still far away to be achieved, mainly due need xenogeneic substances for cell expansion, such as fetal bovine serum (FBS). FBS presents risks regarding pathogens transmissions and internalization animal’s proteins, which can unleash antigenic responses patients after implantation. A wide range venous blood derivatives (VBD) has been reported substitutes...

10.1590/0103-6440201701646 article EN cc-by Brazilian Dental Journal 2017-12-01

Novel poly(vinyl alcohol)/chondroitin sulfate (PVA/CS) composite hydrogels containing hydroxyapatite (HA) or Sr-doped HA (HASr) particles were synthesized by a freeze/thaw method and characterized aiming towards biomedical applications. HASr wet-precipitation added to the in fractions up 15 wt%. Physical-chemical characterizations of included scanning electron microscopy, energy-dispersive spectroscopy, Fourier-transform infrared X-ray diffraction, thermogravimetry, porosity, compressive...

10.1002/jbm.a.37108 article EN Journal of Biomedical Materials Research Part A 2020-09-28

This study analyzed the physical-chemical behavior of 2 bulk fill resin composites (BFCs; Filtek Bulk Fill [FBF], and Tetric-N-Ceram [TBF]) used in 2- 4-mm increments compared them with a conventional composite (Filtek Z250).Flexural strength elastic modulus were evaluated by using 3-point bending test. Knoop hardness was measured at depth areas 0-1, 1-2, 2-3, 3-4 mm. The translucency parameter an optical spectrophotometer. Real-time polymerization kinetics Fourier transform infrared...

10.5395/rde.2021.46.e39 article EN cc-by-nc Restorative Dentistry & Endodontics 2021-01-01

Recientes publicaciones plantean la posible asociación del cannabis (Cannabis sativa) con el desarrollo de periodontitis.

10.22592/ode2018n31a2 article ES cc-by-nc Odontoestomatología 2018-05-21

The objective of this work was to assess the efficacy different proteolytic agents on bond strength pit and fissure sealants bovine enamel. Eighty-four enamel specimens were randomly assigned in groups according sealant applied (HelioSeal F or Dyad Flow). Then, subdivided agent used (n = 7): Group 1, distilled water (control); 2, 10 wt.% Tergazyme®; 3, ZYME®; 4, 10% papain gel; 5, bromelain 6, 5.25 sodium hypochlorite. cell viability solutions assessed through MTT assay. surface prior...

10.3390/dj12070206 article EN cc-by Dentistry Journal 2024-07-04

Objective: To determine the effect of intensity two light curing units on biocompatibility, flexural strength and elastic modulus a composite resin.   Methodology: Two groups Filtek Z250XT (3M ESPE) resin were created, each one photopolymerized using different intensities (<400 mW/cm2 for 40s and> 800 20s). Cell viability was analyzed by MTT assay at 24 48 hours following ISO 10993-5 standard. The 4049 Results: In group with an <400 mW/cm2, cytotoxicity statistically...

10.22592/ode2022n40e222 article EN cc-by-nc Odontoestomatología 2023-03-15

Abstract Background: The COVID-19pandemic has significantly impacted the dental sector worldwide. Methods: impact of pandemic on dentistsfrom Latin America was investigated by an online survey with professionals working in 11 Spanish-speaking countries September–December 2020. invitations were sent to registered professionals. An open campaign promoted social media. questions care routines, work practice changes, andfeelings about pandemic, addition toreasons for engaging...

10.21203/rs.3.rs-764333/v1 preprint EN cc-by Research Square (Research Square) 2021-08-05
Coming Soon ...