- Nutrition and Health in Aging
- Thyroid Cancer Diagnosis and Treatment
- Lipoproteins and Cardiovascular Health
- Thyroid Disorders and Treatments
- Clinical Nutrition and Gastroenterology
- Child Nutrition and Feeding Issues
- Pituitary Gland Disorders and Treatments
- Child Nutrition and Water Access
- Neuroendocrine Tumor Research Advances
- Health and Lifestyle Studies
- Diabetes, Cardiovascular Risks, and Lipoproteins
- Body Composition Measurement Techniques
- Diabetes Management and Research
- Diet and metabolism studies
- Cardiac, Anesthesia and Surgical Outcomes
- Atherosclerosis and Cardiovascular Diseases
- Thyroid and Parathyroid Surgery
- Adrenal and Paraganglionic Tumors
- Hyperglycemia and glycemic control in critically ill and hospitalized patients
- Growth Hormone and Insulin-like Growth Factors
- Peripheral Neuropathies and Disorders
- Adrenal Hormones and Disorders
- Magnesium in Health and Disease
- Neuroblastoma Research and Treatments
- Hormonal Regulation and Hypertension
Hospital Universitario De Cabueñes
2015-2025
Instituto de Investigación Sanitaria del Principado de Asturias
2021-2025
Universidad de Oviedo
2025
Gobierno del Principado de Asturias
2023-2024
Universidad Autónoma de Asunción
2021
Clinica Universidad de Navarra
2019
Hospital Montecelo
2019
Sociedad Española de Farmacología Clínica
2015
Central University Hospital of Asturias
2005-2012
Universidad del Mar
2007
OBJECTIVE Premixed insulin is a commonly prescribed formulation for the outpatient management of patients with type 2 diabetes. The safety and efficacy premixed formulations in hospital setting not known. RESEARCH DESIGN AND METHODS In prospective, open-label trial, we randomized general medicine surgery to receive basal-bolus regimen glargine once daily glulisine before meals (n = 33) or human (30% regular 70% NPH insulin) twice 39). Major outcomes included differences blood glucose (BG)...
Background: A nationwide, prospective, multicenter, cohort study (the Disease-Related caloric-protein malnutrition EChOgraphy (DRECO) study) was designed to assess the usefulness of ultrasound rectus femoris for detecting sarcopenia in hospitalized patients at risk and define cut-off values measures. Methods: Patients according Malnutrition Universal Screening Tool (MUST) underwent handgrip dynamometry, bioelectrical impedance analysis (BIA), a Timed Up Go (TUG) test, studies. European...
Background & aims: the last large multicenter study on disease-related malnutrition (DRM) in Spain (the PREDyCES study) showed a 23.7 % prevalence of malnutrition, according to Nutritional Risk Screening (NRS-2002) tool. The main objective SeDREno was assess hospital upon admission, GLIM criteria, ten years later. Methods: cross-sectional, observational, standard clinical practice, conducted 17 hospitals during period five seven days. Patients were initially screened using Malnutrition...
Abstract I deficiency is still a worldwide public health problem, with children being especially vulnerable. No nationwide study had been conducted to assess the status of Spanish children, and thus an observational, multicentre cross-sectional was in Spain thyroid function schoolchildren aged 6–7 years. The median urinary (UI) thyroid-stimulating hormone (TSH) levels whole blood were used function, respectively. A FFQ determine consumption I-rich foods. total 1981 (52 % male) included. UI...
This paper presents baseline results from the NutriEcoMuscle study, a multicenter observational study conducted in Spain which focused on changes nutritional status, body composition, and functionality post-intensive care unit (ICU) COVID-19 patients following intervention. Assessments at hospital discharge included Subjective Global Assessment (SGA), Leadership Initiative Malnutrition (GLIM) criteria, Barthel index, handgrip strength (HGS) Timed Up-and-Go test, bioelectrical impedance...
Our aim was to determine whether rare APOE pathogenic variants (PV) and the common e2/e3/e4 polymorphism were associated with risk of familial hypercholesterolemia (FH). A total 431 patients who met inclusion criteria for FH next-generation sequenced main candidate genes (LDLR, APOB, PCSK9, APOE, LDLRAP1). 139 (32%) had a variant, including 3 p.Leu167del. Among PV-negatives (n = 292), one homozygous APOE-e2 showed combined phenotype high low-density lipoprotein cholesterol (LDL-C)...
The 72-hour fasting test remains the standard for diagnosis of endogenous hyperinsulinism. We investigated which variables could identify patients at low risk hyperinsulinism, in whom a shortening be considered. This multicenter, retrospective study included 64 individuals (46 women, median age 45 years) without diabetes who underwent tests etiologic hypoglycemia. Pre- and intra-test were collected, including point-of-care glucose trajectories during test. Testing was stopped before 72 h if...
Background: Iodine deficiency during pregnancy may have adverse effects on the neurodevelopment of foetus. Recent studies pregnant women in Asturias (Spain) indicate that nutritional iodine levels are sufficient. The objective this study was to confirm appropriate status and analyse influence ingestion maternal urinary concentration (UIC) thyroid function. Methods: An observational carried out between May June 2017 first trimester from Health Area IV Asturias. completed a questionnaire...
Although coral reef sedimentation is important because it modifies processes like symbioses, reproduction, recruitment and growth, Mexican Pacific studies are lacking. On this regard, spatio-temporal variations in rate were investigated six communities from Oaxaca. During February 2006-January 2007 (excluding April, July August) two sediment structures, with four traps each, randomly installed. Sediment replaced a mean periodicity of 38 days, the sediments washed, filtered, dried weighted...
We discuss the case of a 17-year-old male who at age 7 was diagnosed with celiac disease (CD) together ulcerative colitis (UC) and primary sclerosing cholangitis (PSC).The patient treated gluten-free diet immunosuppressive drugs (azathioprine), currently remains asymptomatic.The patient's younger, 12-year-old sister CD when she 1.5 years old, developed type-I diabetes mellitus, which difficult to control.A family study made, both parents were found be affected silent CD.All DQ2 (+).In...
Malnutrition is a common condition associated with various pathologies such as infections, neoplasms and digestive system disorders. Patients can be managed using different strategies, which include dietary modifications or oral nutritional supplements (ONS). It important to promote good ONS adherence in order attain clinical efficacy cost-effectiveness. Several factors (amount, type, duration tolerability) may have an impact on adherence. PerceptiONS descriptive, cross-sectional...
Thyroid nodules are a common finding. A high-resolution thyroid nodule clinic (HR-TNC) condenses all tests required for the evaluation of into single appointment. We aimed to evaluate clinical outcomes at HR-TNCs.A retrospective cross-sectional multicenter study including data from four HR-TNCs in Spain. evaluated fine-needle aspiration (FNA) indications and association between ultrasound characteristics with cytological histopathological outcomes.A total 2809 were included; FNA was...
Introduction: gastrocolic fistula is an infrequent but severe complication of percutaneous gastrostomy. Clinical suspicion in the presence chronic diarrhea unknown etiology manifesting after radiological gastrostomy (PRG) tube replacement key to early detection and treatment. Case report: we report case a patient with PRG that began developed malnutrition. Initial treatment was not effective, studies were extended finding this CT image. The use discontinued resolution favorable nutritional...