A5065186875- Adipokines, Inflammation, and Metabolic Diseases
- Diet and metabolism studies
- Adipose Tissue and Metabolism
- Regulation of Appetite and Obesity
- Nutrition and Health in Aging
- Diet, Metabolism, and Disease
- Body Composition Measurement Techniques
- Nutrition, Genetics, and Disease
- Bariatric Surgery and Outcomes
- Liver Disease Diagnosis and Treatment
- Clinical Nutrition and Gastroenterology
- Cannabis and Cannabinoid Research
- Cardiovascular Disease and Adiposity
- Pancreatic function and diabetes
- Metabolism, Diabetes, and Cancer
- Obesity, Physical Activity, Diet
- Diabetes Treatment and Management
- Muscle metabolism and nutrition
- Diabetes, Cardiovascular Risks, and Lipoproteins
- Vitamin D Research Studies
- Apelin-related biomedical research
- Cerebral Palsy and Movement Disorders
- Bone health and osteoporosis research
- Genetic Associations and Epidemiology
- Pharmacology and Obesity Treatment
Hospital Clínico Universitario de Valladolid
2016-2025
Universidad de Valladolid
2016-2025
Sociedad Española de Endocrinología y Nutrición
2018-2020
Hospital Universitario Río Hortega
2011-2017
Background: A nationwide, prospective, multicenter, cohort study (the Disease-Related caloric-protein malnutrition EChOgraphy (DRECO) study) was designed to assess the usefulness of ultrasound rectus femoris for detecting sarcopenia in hospitalized patients at risk and define cut-off values measures. Methods: Patients according Malnutrition Universal Screening Tool (MUST) underwent handgrip dynamometry, bioelectrical impedance analysis (BIA), a Timed Up Go (TUG) test, studies. European...
Background and aims: The relationship between obesity bone metabolism is controversial. In recent decades, the protective role of in development osteoporosis questioned. aims this study are following: to evaluate differences turnover markers postmenopausal women with without compare risk fracture at five years these groups. Methods: An observational longitudinal prospective cohort (O) (body mass index (BMI) > 30 kg/m2) non-obesity (NoO) (BMI < designed. 250 included (NoO: 124 (49.6%) O: 126...
(1) Background: The aim was to validate an AI-based system compared the classic method of reading ultrasound images rectus femur (RF) muscle in a real cohort patients with disease-related malnutrition. (2) Methods: One hundred adult DRM aged 18 85 years were enrolled. risk assessed by Global Leadership Initiative on Malnutrition (GLIM). variation, reproducibility, and reliability measurements for RF subcutaneous fat thickness (SFT), (MT), cross-sectional area (CSA), measured conventionally...
Amyotrophic lateral sclerosis (ALS) is a progressive disease with high prevalence of malnutrition that can influence prognosis. The main objective this study to compare the validity muscle ultrasonography in diagnosis and prognosis patients ALS. Methods: This prospective observational analyzes nutritional status at beginning monitoring. morphofunctional assessment included examination anthropometric variables such as weight, height, body mass index (BMI), arm circumference, calf...
Objectives: The aim of this investigation was to evaluate the discrepancies between bioelectrical impedance analysis (BIA) and computed tomography (CT) in assessing skeletal muscle mass identifying low patients with colorectal cancer. Methods: This study recruited 137 cancer from February 2028 December 2023. CT scans were analyzed at Lumbar 3 vertebral level determine area muscle, which then utilized estimate whole-body mass. [BIA] also employed measure muscle. Both values [kg] divided by...
This study aimed to evaluate the effects of an oral nutritional supplement (ONS) enriched with hydroxy-methyl-butyrate (HMB) in subjects disease-related malnutrition (DRM) and monitor these ultrasound Imaging System, based on artificial intelligence, a real-world study. Fifty consecutive adult patients DRM were enrolled. The was diagnosed by Global Leadership Initiative Malnutrition (GLIM) criteria. For 3 months, received education, medical nutrition therapy started adapted diet two servings...
meal replacement (MR) diets consist of replacing one or more meals. The objective was to evaluate the effect a MR diet on weight reduction and metabolic syndrome (MS). real-world study designed with diet. first phase consisted (12 weeks); second reintroduction foods following low-calorie (-300 -500 calories per day) weeks). Anthropometric biochemical measurements were performed at initiation study; 12 24 weeks. mean age 45.6 ± 3.5 years (n = 364). There 100 males (27.5 %) 264 females (72.5...
Background/Objectives: Epigenetic clocks have emerged as a tool to quantify biological age, providing more accurate estimate of an individual’s health status than chronological helping identify risk factors for accelerated aging and evaluating the reversibility therapeutic strategies. This study aimed evaluate potential association between epigenetic acceleration age obesity, well determine whether nutritional interventions body weight loss could slow down this acceleration. Methods:...
Many elderly patients with COVID-19 are at risk of malnutrition. The aim our study was to evaluate the malnutrition and sarcopenia in R-MAPP (Remote-Malnutrition APP).A cross-sectional 337 consecutive outpatients ≥65 years who attended Central Emergency Hospital Castilla y Leon conducted. In all patients, protocol (Malnutrition Universal Screening Tool [MUST] Simple Questionnaire Rapidly Diagnose Sarcopenia [SARC-F]) realized.The mean age 86.1 ± 8.7 years, a sex distribution 167 males...
BackgroundThe molecular mechanisms underlying the potential health benefits of a ketogenic diet are unknown and could be mediated by epigenetic mechanisms.ObjectiveTo identify changes in obesity-related methylome that induced weight loss or dependent on ketosis subjects with obesity underwent very-low calorie (VLCKD).MethodsTwenty-one patients (n = 12 women, 47.9 ± 1.02 yr, 33.0 0.2 kg/m2) after 6 months VLCKD normal volunteers 50.3 6.2 yrs, 22.7 1.5 were studied. Data from Infinium...
Nutritional ultrasonography is an emerging technique for measuring muscle mass and quality. The study aimed to evaluate the relationship between parameters of body quality with other morphofunctional assessment in patients disease-related malnutrition (DRM).
Common polymorphisms of the fat mass and obesity associated gene (FTO) have been linked to in some populations. One these genetic variants (rs9939609) has related an increased risk obesity.Our aim was evaluate weight loss adipocytokine levels after two hypocaloric diets with different macronutrient distribution obese subjects RS9939609 variant.305 patients were enrolled a prospective way. In basal visit, randomly allocated during 3 months low carbohydrates fat.After treatment both genotypes,...
Introduction. Phase angle (PhA) has been suggested to be an indicator of body cell mass and nutritional status. Clinically, the phase supposedly reflects membrane function, higher angle, better is function. Muscle ultrasound (US) emerging assessment technique. Objective. The aim this study was investigate usefulness correlation PhA with muscle US quadriceps rectus femoris (QRF) in obese female subjects relationship quality life physical performance. Material Methods. In a total healthy 50...
Adiponectin is one of the most important adipokines in human beings. Obesity and sarcopenia are associated with a low-level chronic inflammatory status, adiponectin plays an anti-inflammatory role.
The common polymorphism rs9939609 of the fat mass- and obesity-associated gene (FTO) has been linked to obesity. Our aim was investigate its role in weight loss after administration a high-protein/low-carbohydrate diet compared standard hypocaloric (1,000 kcal/day).During 9 months, 195 patients were randomly allocated high-protein (HP diet) (S diet).With HP diet, BMI (-1.9 ± 1.2 vs. -2.10 1.8; p < 0.05), (-6.5 2.1 -10.1 4.1 kg; mass (-3.9 3.2 -6.0 3.4 0.05) waist circumference (-5.7 5.0 -9.9...
<b><i>Background and Aims:</i></b> The aim of this study was to determine the association single nucleotide polymorphism rs1501299 in <i>ADIPOQ </i>gene with body weight, insulin resistance, serum adipokine levels metabolic syndrome (MetS). <b><i>Methods:</i></b> involved a population 1,007 adult obese subjects. Parameters like fat mass, waist circumferences, blood pressure, fasting glucose, C-reactive protein, concentration,...
Abstract Background/objectives In patients with acute stroke, the presence of hyperglycaemia has been associated higher morbidity and less neurological recovery. The aim study was to evaluate impact a diabetes specific enteral nutrition (EN) formula on glycaemia, comorbidities mortality in admitted first episode stroke who received complete EN. Methods This prospective randomised controlled trial. Patients did not have diagnosis mellitus required nasogastric tube feeding. registered code...
Background: User-friendly tools for assessing nutrition status and interventions in malnourished patients are crucial. This study evaluated the effectiveness of a personalised intervention using novel oral nutritional supplement AI-supported morphofunctional assessment to monitor clinical outcomes with disease-related malnutrition (DRM). Methods: prospective observational involved receiving concentrated high-protein, high-calorie ONS (cHPHC-ONS), per usual practice. Comprehensive assessments...
Previous studies addressing the changes of resistin concentrations in morbidly obese patients after bariatric surgery have yielded conflicting results. The purpose present study was to investigate serum levels 1 year biliopancreatic diversion without diabetes mellitus. A cohort 39 mellitus operated. Biochemical and anthropometric evaluation were realized at basal visit each visit. frequency with hypertension hyperlipidemia recorded Overall mean patient age 44.8 ± 14.1, preoperative BMI 47.3...