- Diet and metabolism studies
- Adipose Tissue and Metabolism
- Diet, Metabolism, and Disease
- Bariatric Surgery and Outcomes
- Pharmacology and Obesity Treatment
- Muscle metabolism and nutrition
- Dietary Effects on Health
- Body Contouring and Surgery
- Gut microbiota and health
- Health and Lifestyle Studies
- Adipokines, Inflammation, and Metabolic Diseases
- Gastrointestinal motility and disorders
- Liver Disease Diagnosis and Treatment
- Dermatological and COVID-19 studies
- Fatty Acid Research and Health
- Regulation of Appetite and Obesity
- Body Composition Measurement Techniques
- Cardiovascular Health and Disease Prevention
- Cardiovascular Function and Risk Factors
- Eating Disorders and Behaviors
- Epigenetics and DNA Methylation
- Ovarian function and disorders
- Breast Implant and Reconstruction
- Cardiovascular Disease and Adiposity
- Metabolism, Diabetes, and Cancer
PronoKal Group (Spain)
2016-2025
Instituto de Investigación Sanitaria de Santiago
2019-2024
Servicio Gallego de Salud
2019-2024
Complejo Hospitalario Universitario de Santiago
2019-2024
Fundación Pronokal
2020-2022
Instituto Estadual de Diabetes e Endocrinologia Luiz Capriglione
2019
Hospital de Sant Pau
2018
Yahoo (Spain)
2015
Abstract Brackground: The safety and tolerability of very low-calorie-ketogenic (VLCK) diets are a current concern in the treatment obese type 2 diabetes mellitus (T2DM) patients. Objective: Evaluating short-term VLCK diet (<50 g carbohydrate daily) an interventional weight loss program including lifestyle behavioral modification support (Diaprokal Method) subjects with T2DM. Methods: Eighty-nine men women, aged between 30 65 years, T2DM body mass index 35 kg m − participated this...
Abstract Context: Common concerns when using low-calorie diets as a treatment for obesity are the reduction in fat-free mass, mostly muscular that occurs together with fat mass (FM) loss, and determining best methodologies to evaluate body composition changes. Objective: This study aimed very-low-calorie ketogenic (VLCK) diet-induced changes of obese patients compare 3 different used those Design: Twenty followed VLCK diet 4 months. Body assessment was performed by dual-energy X-ray...
Psychological well-being and hunger food control are two relevant factors involved in the success of weight-loss therapy treating obesity. Thus, this study aims to evaluate alcohol cravings, physical sexual activity, sleep, life quality (QoL) obese patients following a very low-calorie ketogenic (VLCK) diet, as well role weight lost ketosis on these parameters. A battery psychological test was performed twenty (12 females, 47.2 ± 10.2 year BMI 35.5 4.4) through course 4-month VLCK diet four...
The resting metabolic rate (RMR) decrease, observed after an obesity reduction therapy is a determinant of short-time weight regain. Thus, the objective this study was to evaluate changes in RMR, and associated hormonal alterations obese patients with very low-calorie ketogenic (VLCK)-diet induced severe body (BW) loss.From 20 who lost 20.2 kg BW 4-months VLCK-diet, blood samples composition analysis, determined by DXA MF-Bioimpedance, RMR indirect calorimetry, were obtained on four...
BBackground: Currently the treatment of nonalcoholic fatty liver disease (NAFLD) is based on weight loss through lifestyle changes, such as exercise combined with calorie-restricted dieting. Objectives: To assess effects a commercially available program Very Low-Calorie Ketogenic Diet (VLCKD) Visceral Adipose Tissue (VAT) and fat content compared to standard diet (LC). As secondary aim we evaluated effect stiffness measurements. Methods: Open, randomized, controlled, prospective pilot study....
Scope Little is known about the changes that a very‐low‐calorie ketogenic diet (VLCKD) produces in gut microbiota or effect of synbiotics during diet. The aim this study to evaluate produced by VLCKD and synbiotic supplementation. Methods results A randomized, single‐blind, parallel‐design trial conducted 33 obese patients who follow weight‐loss program (PnK‐Method) include followed low‐calorie (LCD). Subjects are randomly allocated three groups: one supplemented with synbiotics, second...
The preservation of muscle mass and function after weight loss therapy is currently a considerable challenge in the fight against obesity. Muscle secretes proteins called myokines that have relevant functions regulation metabolism health. This study was aimed to evaluate whether very low-calorie ketogenic (VLCK) diet may modulate myokine levels, addition changes body composition, compared standard, balanced (LC) or bariatric surgery patients with Body ketosis, insulin sensitivity were...
The aim of this study isto assess the efficacy a very low-calorie ketogenic diet (VLCKD) method vs Mediterranean (LCD) in obese polycystic ovary syndrome (PCOS) women reproductive age.Randomized controlled open-label trial was performed study. treatment period 16 weeks; VLCKD for 8 weeks then LCD weeks, according to Pronokal® (experimental group; n = 15) (control 15). Ovulation monitoring carried out at baseline and after while clinical exam, bioelectrical impedance analysis (BIA),...
BackgroundThe molecular mechanisms underlying the potential health benefits of a ketogenic diet are unknown and could be mediated by epigenetic mechanisms.ObjectiveTo identify changes in obesity-related methylome that induced weight loss or dependent on ketosis subjects with obesity underwent very-low calorie (VLCKD).MethodsTwenty-one patients (n = 12 women, 47.9 ± 1.02 yr, 33.0 0.2 kg/m2) after 6 months VLCKD normal volunteers 50.3 6.2 yrs, 22.7 1.5 were studied. Data from Infinium...
Options for treatment of obesity include dietary approaches and bariatric surgery. Previous studies have shown that weight loss interventions an impact on gut microbiota. However, a pattern microbiota changes associated with independently the type intervention has not been described yet. This study includes 61 individuals who followed different strategies in three trials: 21 hypocaloric Mediterranean diet (MedDiet), 18 very-low-calorie ketogenic (VLCKD) 22 patients underwent sleeve...
Weight loss after bariatric surgery decreases the earlier expansion of adventitial vasa vasorum (VV), a biomarker early atheromatous disease. However, no data are available regarding weight achieved by very low calorie ketogenic diets (VLCKD) on VV and lipid-based atherogenic indices. A randomized clinical trial was performed to examine changes in density 20 patients with moderate obesity who underwent 6-month diet (VLCKD, 600-800 kcal/day), 10 participants hypocaloric based Mediterranean...