A5063445538- Diet and metabolism studies
- Diabetes Management and Research
- Diabetes Treatment and Management
- Nutrition and Health in Aging
- Gut microbiota and health
- Nutritional Studies and Diet
- Vitamin D Research Studies
- Dietary Effects on Health
- Metabolism, Diabetes, and Cancer
- Body Composition Measurement Techniques
- Hyperglycemia and glycemic control in critically ill and hospitalized patients
- Bone health and osteoporosis research
- Pituitary Gland Disorders and Treatments
- Clinical Nutrition and Gastroenterology
- Diabetes, Cardiovascular Risks, and Lipoproteins
- Diabetes Management and Education
- Helicobacter pylori-related gastroenterology studies
- Diabetes and associated disorders
- Health and Lifestyle Studies
- Diet, Metabolism, and Disease
- Parathyroid Disorders and Treatments
- Liver Disease Diagnosis and Treatment
- Pancreatic function and diabetes
- Obesity, Physical Activity, Diet
- Biochemical Analysis and Sensing Techniques
Instituto de Salud Carlos III
2016-2025
Centro de Investigación Biomédica en Red
2016-2025
Instituto de Investigación Biosanitaria de Granada
2012-2025
Hospital Universitario Virgen de las Nieves
2020-2024
Spanish Biomedical Research Centre in Physiopathology of Obesity and Nutrition
2019-2024
Universidad de Granada
2024
Hospital Universitario Virgen del Rocío
2023
Green Lane Hospital
2023
Hospital Clínico Universitario Virgen de la Victoria
2012-2021
Instituto de Investigación Biomédica de Málaga
2015-2021
To determine the usefulness of measuring hemoglobin A(1c) (A1C), alone or combined with fasting glucose test, compared oral tolerance test (OGTT) for reassessment carbohydrate metabolism status in postpartum women a history gestational diabetes mellitus (GDM).We evaluated by performing OGTT and A1C tests 231 prior GDM 1 year after delivery.The prevalence abnormal was 45.89% criterion, 19.05% 38.10% 46.75% A1C-fasting criteria. Using as gold standard, according to criterion had 22.64%...
The relationship between 25-hydroxyvitamin D [25(OH)D] and obesity type 2 diabetes is not completely understood. Vitamin receptor (VDR) expression in adipose tissue (AT) related to might be regulated by 1,25-dihydroxyvitamin D3 [1,25(OH)2D3].To analyze serum 25(OH)D VDR gene AT according body mass index (BMI) glycemic status the effect of 1,25(OH)2D3 on BMI.Two cohorts were studied: 1) 118 subjects classified their BMI (lean, overweight, obese, or morbidly obese [MO]) (normoglycemic [NG]...
Hyperglycemia may increase mortality in patients who receive total parenteral nutrition (TPN). However, this has not been well studied noncritically ill (i.e., the nonintensive care unit setting). The aim of study was to determine whether mean blood glucose level during TPN infusion is associated with increased hospitalized patients.This prospective multicenter involved 19 Spanish hospitals. Noncritically were prescribed included prospectively, and data collected on demographic, clinical,...
Changes in the intestinal microbial community and some metabolic disturbances, including obesity type2 diabetes, are related. Glucagon-like peptide-1 (GLP-1) regulates glucose homeostasis. Microbiota have been linked to incretin secretion. Antibiotic use causes changes diversity composition. Our aim was evaluate relationship between microbiota GLP-1 A prospective case-control study with a Helicobacter pylori-positive patient model involving subjects under eradication therapy (omeprazole,...
Background H. pylori infection and eradication cause perturbations of the gut microbiome. The microbiota has been identified as a potential contributor to metabolic diseases. We evaluate whether these alterations in intestinal composition produced by its posterior with antibiotic treatment could be associated glucose homeostasis metabolically healthy subjects. Methods Forty adult patients infected 20 control subjects were recruited. evaluated before two months after (omeprazole,...
Metformin modifies the gut microbiome in type 2 diabetes and gastrointestinal tolerance to metformin could be mediated by microbiome.We enrolled 35 patients with not receiving treatment due suspected intolerance. was reintroduced at 425 mg, increasing mg every two weeks until reaching 1700 per day. According occurrence of metformin-related symptoms, were classified into three groups: early intolerance, non-tolerant, tolerant. Gut microbiota profiled 16 S rRNA. This sequencing aimed determine...
Introduction Bioelectrical impedance analysis (BIA) serves as a method to estimate body composition. Parameters such phase angle (PA), standardized (SPA), mass cell (BCM), BCM index (BCMI), and fat-free (FFM) might significantly impact the prognosis of head neck cancer (HNC) patients. The present study aimed investigate whether bioelectrical parameters can be used predict survival in HNC population establish optimal cutoff points for predictive accuracy. Methods A multicenter observational...
OBJECTIVE To assess the impact of a telemedicine visit using platform Diabetic compared with face-to-face on clinical outcomes, patients’ health-related quality life (HRQoL), and physicians’ satisfaction in patients type 1 diabetes. RESEARCH DESIGN AND METHODS PLATEDIAN (Telemedicine Metabolic Control Type Diabetes Mellitus Andalusian Patients) (NCT03332472) was multicenter, randomized, 6-month follow-up, open-label, parallel-group controlled study performed diabetes suboptimal metabolic...
Dietary guidelines emphasize the importance of a varied diet to provide an adequate nutrient intake. However, older age is often associated with consumption monotonous diets that can be nutritionally inadequate, increasing risk for development or progression diet-related chronic diseases, such as metabolic syndrome (MetS). To assess association between dietary diversity (DD) and intake adequacy identify demographic variables DD, we cross-sectionally analyzed baseline data from PREDIMED-Plus...
Objective: Polyamines are naturally occurring cationic molecules present in all living cells. Dysregulation of circulating polyamines has been reported several conditions, but little is known about the levels serum chronic metabolic disorders such as type 2 diabetes (T2D). Therefore, aim this study was to evaluate polyamine-related metabolome a cohort syndrome individuals with and without T2D. Design methods: This nested case⁻control within PREDIMED-Plus trial that included 44 patients T2D...
Objective The hypertriglyceridemic waist (HTGW) phenotype is characterized by abdominal obesity and high levels of triglycerides. In a cross‐sectional assessment PREDIMED‐Plus trial participants at baseline, HTGW prevalence was evaluated, associated risk factors were analyzed, the lifestyle individuals with metabolic syndrome examined. Methods A total 6,874 aged 55 to 75 BMI ≥ 27 < 40 kg/m 2 included classified presence (HTGW + ) or absence − (waist circumference: men 102 cm, women 88 cm;...